Results 101 to 110 of about 7,687,713 (299)
Brazilian Journal of Medical and Biological Research, 2012 A dendritic cell (DC)-based vaccine strategy could reduce the risk of recurrence and improve the survival of breast cancer patients. However, while therapy-induced apoptosis of hepatocellular and colorectal carcinoma cells can enhance maturation and ...
Jin Zheng +10 more
doaj +2 more sources
Leveraging Microphysiological Systems to Facilitate Neutrophil‐Based Cancer Immunotherapy
Advanced Science, EarlyView.Microphysiological systems are emerging as powerful human‐relevant platforms for studying neutrophil biology in cancer. Current applications of spheroids, organoids, and organ‐on‐a‐chip models are reviewed, together with future opportunities in behaviorome profiling, multi‐omics integration, personalized medicine, immune crosstalk, and multi‐organ ...
Shuai Shao +2 more
wiley +1 more source
The anti-apoptotic effect of c-fos in drug-resistant breast cancer cells
Zhongguo aizheng zazhi, 2014 Background and purpose: Breast cancer is one of the most common carcinoma among female patients with high mortalities. Drug-resistance is the major reason that leads to chemotherapy failure in clinical practice.
彭洪薇 +4 more
doaj
Activity of docetaxel and peptoids in MCF-7 and MCF-7/TxT50 cells.
, 2014 MCF-7/TxT50 cells were selected by docetaxel screening and are resistant due to overexpression of MDR1. Figures show the cell viability of MCF-7 and MCF-7/TxT50 cells treated with docetaxel (A), peptoid 1 (B) and 1achiral (C) for 72 h. Cell viability was
Stephen B. Willingham (528885) +6 more
core +1 more source
Advanced Science, EarlyView.This work develops a metabolic sharing strategy that employs cytidine monophosphate (CMP) to competitively reprogram floxuridine (FUDR) pyrimidine metabolism in colorectal tumor cells. Elevated intracellular FdUMP induces nucleotide imbalance, drives mitochondrial DNA release and cGAS‐STING innate immune cascade activation, and potentiates robust ...
Chao Wang +10 more
wiley +1 more source
Mechanism of AMPK-enhanced chemosensitivity of breast cancer MCF-7/adr cells to adriamycin
Zhongguo aizheng zazhi, 2016 Background and purpose: AMP-activated protein kinase (AMPK) plays an important role in the regulation of cell metabolism and energy balance and is associated with cell proliferation, survival and multiple signaling pathways.
崔文贤, 许柯青, 李元国
doaj
Involvement of caspase activation in MCF-7 and MCF-7/ADR cells after treated with EVO for 48 h.
, 2014 EVO increase the activities of caspase 3/7 (A) and caspase 9 (B) in MCF-7 and MCF-7/ADR cells by a dose-dependent manner.
Shengpeng Wang (565046) +5 more
core +1 more source
Advanced Science, EarlyView.SOX30 drives triple‐negative breast cancer (TNBC) metastasis through a dual mechanism: direct activation of the TNFR2/NF‐κB signaling cascade and subsequent CCL20‐mediated recruitment of tumor‐associated macrophages (TAMs) into the tumor microenvironment.
Pingping Gao +10 more
wiley +1 more source
Biomimetic Scaffold‐Based 3D Models for Decoding Cancer Biology and Advancing Therapy
Advanced Science, EarlyView.A timeline of the research history of 3D biomimetic scaffold materials and platforms. With advances in biomimetic materials and 3D scaffold technologies, their functional scope has expanded from mimicking basic physical and biochemical properties to increasingly replicating complex pathophysiological processes.
Haitao Zhao +10 more
wiley +1 more source
Proteomic Comparison of MCF-7 Tumoursphere and Monolayer Cultures
PLoS ONE, 2012 Breast cancer is a heterogeneous disease, composed of tumour cells with differing gene expressions and phenotypes. Very few antigens have been identified and a better understanding of tumour initiating-cells as targets for therapy is critically needed.
Morrison, Brian J +7 more
openaire +5 more sources