Results 131 to 140 of about 114,577 (260)

1‐(Acetylamino)thioxanthones and Derivatives: Synthesis From 1‐Halogenothioxanthones and Biological Properties

European Journal of Organic Chemistry, EarlyView.
The conversion of 1‐halogenothioxanthones into 1‐(acetylamino) derivatives and their NaH‐mediated cyclization have been optimized. This rapid method yields thiochromeno[4,3,2‐de]quinol‐2‐ones that exhibit promising in vitro anticancer activity. Institute and/or researcher Bluesky usernames: https://bsky.app/profile/iscr‐rennes.bsky.social.
Najet Ballagha, Frédéric Lassagne, William Erb, Isabelle Rouaud, Sophie Tomasi, Ziad Fajloun, Mona El Samarji, Mohamad Rima, Anamaria Mendonça Santos, Laurent Picot, Valérie Thiéry, Hédi M’Rabet, Florence Mongin   +12 more
wiley   +1 more source

Phytochemicals and Health Benefits of American Ginseng (Panax quinquefolius L.): Current Knowledge and Future Perspectives

Food Safety and Health, EarlyView.
This review summarizes the chemical constituents and functional characteristics of American ginseng, aiming to provide references for its development and application. ABSTRACT American ginseng, a perennial herbaceous plant, is recognized for its significant medicinal properties and has attracted considerable attention due to its diverse phytochemical ...
Wei Geng, Ning Zhou, Jinqian Yu, Yanling Geng, Xiao Wang, Yannan Chen   +5 more
wiley   +1 more source

Resveratrol as a Modulator of Adriamycin-, Taxol-, and Cisplatin-Induced Cytotoxicity in MCF-7 Breast Cancer Cells. [PDF]

Int J Mol Sci
Biltekin B, Uzun H, Bilir A.
europepmc   +1 more source

Antimicrobial Sensitivity Profile and Resistance Gene Research in Escherichia coli Isolated From Water and Fish From Lagoa da Conceição, Florianópolis, SC, Brazil

Food Safety and Health, EarlyView.
This paper highlights a concerning scenario of environmental contamination by multidrug‐resistant bacteria, underscoring the need for integrated surveillance and control strategies to address antimicrobial resistance in aquatic environments within the context of One Health.
Francisco Lucas de Amorim Nascimento, Luan Amaral Alexandre, Cynthia Farias Manassi, Alice Cristina da Silva, Luísa Aimée Schmitt Lobe, Gustavo Rocha, Mateus Rocha Ribas, Victor Wolleck, Gabriele Caroline Gottschalk de Abreu, Alessandra Valéria Vortmann, Sheila Mello da Silveira, Rodrigo Barcellos Hoff, Jussara Kasuko Palmeiro, Silvani Verruck   +13 more
wiley   +1 more source

Novel SOAT inhibitors block DHEAS transport and suppress proliferation in MCF-7 breast cancer cells. [PDF]

Sci Rep
Karakus E, Leiting S, Daude M, Diederich WE, Geyer J.   +4 more
europepmc   +1 more source

New Medical Schools, Access to Physicians, and Health Outcomes: Evidence From Japan

Health Economics, EarlyView.
ABSTRACT We analyse the impact of the construction of medical schools and associated university hospitals in Japan during the 1970s, which was primarily driven by ‘One Prefecture, One Medical School Policy’ (OPOMS). We find that the number of physicians increased significantly in prefectures where a medical school was built, and this effect persisted ...
Kisho Hoshi
wiley   +1 more source

RETRACTION: Synthesis, Characterization, and Anticancer Activity of New Quinazoline Derivatives against MCF-7 Cells. [PDF]

ScientificWorldJournal
Journal TSW.
europepmc   +1 more source

In Vitro Raman Spectroscopic Characterization of Docetaxel‐Loaded Polymeric Nanoparticles

Helvetica Chimica Acta, EarlyView.
The chemotherapeutic drug docetaxel(DTX) is nanoformulated using Soluplus, Soluplus–TPGS, and Pluronic micelles and characterized by label‐free in vitro FT‐Raman spectroscopy. Distinct DTX Raman signatures confirm successful drug incorporation, while spectral decomposition reveals the superior performance of Soluplus–TPGS mixed micelles, paving the way
Sankar Jana, Emma Reig‐Martí, Constanze Schultz, Michael Schmitt, Tobias Meyer‐Zedler, S M Miftahul Islam, Iwan W. Schie, Ibane Abasolo, Miriam Royo, Juergen Popp   +9 more
wiley   +1 more source

Antioxidant, antimicrobial, and apoptosis-related activities of Azadirachta indica (Neem) leaf extract in MCF-7 and A549 cell lines. [PDF]

Sci Rep
Toson EA, Marzouk M, Rezk NA, Rabei S, Zahran RF.   +4 more
europepmc   +1 more source

Targeting eIF5A combats breast cancer progression by ClpP‐dependent mitochondrial oxidative stress

Interdisciplinary Medicine, EarlyView.
This study identified the eIF5A‐ClpP axis as a key driver of breast cancer progression. Targeting eIF5A suppresses tumor growth by inducing ClpP‐dependent mitochondrial oxidative stress, revealing a novel therapeutic vulnerability. Abstract Breast cancer (BC) poses a persistent global health challenge, necessitating new therapeutic targets.
Jinmei Zhu, Baoyuan Tang, Bei Xie, Haohua Deng, Haitang Yang, Lei Ma, Ziqing Zhang, Yicheng Ma, Xingyuan Ma, Shuaiyang Wang, Jing Li, Lei Zhao, Wengui Shi, Linjing Li   +13 more
wiley   +1 more source