Results 61 to 70 of about 114,577 (260)

An estrogen-dependent esterase activity in MCF-7 cells

Journal of Steroid Biochemistry, 1987
The presence of steroidal esters in hormonally sensitive tissues lends importance to the esterases which convert the biologically inactive adducts to the parent potent forms. Accordingly, esterase-activities were studied in a human breast cancer model--the MCF-7 cell line. Tritiated estradiol esters- estradiol-17-acetate (EA), estradiol-17-valerate (EV)
J, Katz, T H, Finlay, S, Banerjee, M, Levitz   +3 more
openaire   +2 more sources

A Naphthalimide‐Based NIR‐Emissive AIE Photosensitizer for Synergistic Apoptosis/Ferroptosis‐Mediated Antitumor Therapy and Broad‐Spectrum Bacterial Inactivation With Rapid Wound Healing

Advanced Healthcare Materials, EarlyView.
An ionic naphthalimide AIE photosensitizer (PS), TPAPV‐NIM‐M, anchors to cellular and bacterial membranes, emits in the far‐red/near‐infrared (NIR) region, and efficiently generates reactive oxygen species (ROS) under white light. Its membrane‐localized photodynamic action drives apoptosis/ferroptosis‐mediated tumor suppression and broad‐spectrum ...
Sayed Mir Sayed, Zeeshan Tahir, Fahri Alkan, Yavuz Nuri Ertas   +3 more
wiley   +1 more source

HUMAN PREADIPOCYTES INHIBIT PROLIFERATION OF MCF-7 BREAST CANCER CELL LINE [PDF]

Acta Medica Iranica, 2006
Cancer cell-stromal cell interaction plays a crucial role in the growth and invasion of tumor cells of various organs. It has been recently suggested that adipocytes and preadipocytes, two specific types of stromal cells, affect the biological behavior ...
I. Ragerdi Kashani, M. Barbarestani, F. Etesam, M. A. Shokrgozar, M. A. Abdolvahabi, P. Haddad, M. H. Noori Mokohi M. Hosseini   +6 more
doaj   +2 more sources

Thermally Modulated Metasurface Sensor for Dynamic and Time‐Resolved Isolation of Extracellular Vesicles

Advanced Materials, EarlyView.
A thermally adaptive plasmonic metasurface, functionalized with poly(N‐isopropylacrylamide) (PNIPAM) and anti‐CD63 antibodies, enables precise, on‐demand capture and release of extracellular vesicles (EVs). Delivering high recovery, improved purity, and intact vesicle structure, the platform offers a versatile, label‐free solution for real‐time EV ...
Beyza Nur Kucuk, Eylul Gulsen Yilmaz, Yusuf Aslan, Emre Ece, Özgecan Erdem, Murat Alp Gungen, Bengi Özgün Öztürk, Fatih Inci   +7 more
wiley   +1 more source

Effect of concurrent or sequential exemestane combined with radiation on radiosensitivity of MCF-7 cells

Zhongguo aizheng zazhi, 2016
Background and purpose: Radiotherapy and endocrine therapy are both important parts of adjuvant therapy for breast cancer, yet few studies have been conducted focusing on the interaction between radiation and endocrine therapy.
陈　刚, 金冶宁, 张顺康
doaj  

The Effect of Curcumin on Staphylococcus aureus Resistant to Aminoglycosides Isolated from Burn and Wound Infections

Medical Journal of Babylon
Background: Thermal injury destroys the skin, the natural barrier to the external environment. As a result the burned area is prone to infection and colonization of microorganisms. The most common pathogenic colonizing bacteria are Staphylococcus aureus.
Ola Abbas Khdhair, Yazi Abdullah Jassim
doaj   +1 more source

Triphenylphosphonium-modified mitochondria-targeted paclitaxel nanocrystals for overcoming multidrug resistance

Asian Journal of Pharmaceutical Sciences, 2019
Mitochondria are currently known as novel targets for treating cancer, especially for tumors displaying multidrug resistance (MDR). This present study aimed to develop a mitochondria-targeted delivery system by using triphenylphosphonium cation (TPP ...
Xue Han, Ruijuan Su, Xiuqing Huang, Yingli Wang, Xiao Kuang, Shuang Zhou, Hongzhuo Liu   +6 more
doaj   +1 more source

Turning Unpredictable Biomolecule Adsorption to Controlled Corona Formation: Focus on Carbon Nanomaterials

Advanced Materials, EarlyView.
Controlling the protein corona formation onto carbon nanomaterials (CNMs) enhances their functionalities as platforms for cancer theranostics. Here, we reviewed the effects of the intrinsic and acquired properties of CNMs on protein corona formation, the consequent biological and toxicological outcomes, and the strategies to reshape corona formation ...
Yajuan Zou, Yalei Hu, Jie Yu, Naoki Komatsu, Yuta Nishina, Alberto Bianco   +5 more
wiley   +1 more source

Combination of 3D and 2D Small and Wide Angle X‐Ray Scattering Imaging Reveals Diminished Bone Quality in the Superior Human Femoral Neck Cortex

Advanced Materials, EarlyView.
Combined 2D and 3D X‐ray scattering imaging is used to analyse nanostructural properties in the inferior and superior cortex of 78 human femoral necks from 44 donors. The methodology allows for increased interpretation of nanostructure in a statistically relevant dataset, revealing nanostructural differences in anatomical locations critical to clinical
Torne Tänzer, Tatiana Kochetkova, Arthur Baroni, Mathieu Simon, Mads Carlsen, Santiago Fernandez Bordin, Manuel Guizar‐Sicairos, Philippe Zysset, Marianne Liebi   +8 more
wiley   +1 more source

Negotiating in a Foreign Land: Understanding the Curious Interactions Between Intracellular Mitochondria and Internalized Nanoparticles

Advanced Materials Interfaces, EarlyView.
Therapeutic nano‐drug delivery systems interact with cellular mitochondria in a multitude of ways. While the complexity of such interactions disrupts the mitochondrial electron transport chain and increases reactive oxygen species production, thereby contributing to nanoparticle toxicity, they also present unique theranostic opportunities in diseases ...
Sourav Bhattacharjee
wiley   +1 more source