Results 41 to 50 of about 209,877 (306)
Scientific Reports, 2023 Breast cancer has become the most prevalent cancer, globally. Adriamycin is a first-line chemotherapeutic agent, however, cancer cells acquire resistance to it, which is one of the most common causes of treatment failure.
Wenna Shao +6 more
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Acta Pharmaceutica Sinica B, 2021 Resistance to breast cancer (BCa) chemotherapy severely hampers the patient's prognosis. MicroRNAs provide a potential therapeutic prospect for BCa. In this study, the reversal function of microRNA34a (miR34a) on doxorubicin (Dox) resistance of BCa and ...
Xiaoxia Yang +7 more
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Comparative proteomics study of proteins involved in induction of higher rates of cell death in mitoxantrone-resistant breast cancer cells MCF-7/MX exposed to TNF-α [PDF]
Iranian Journal of Basic Medical Sciences, 2020 Objective(s): Resistance to medications is one of the main complications in chemotherapy of cancer. It has been shown that some multidrug resistant cancer cells indicate more sensitivity against cytotoxic effects of TNF-α compared to their parental cells.
saeed Norouzi +5 more
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The molecular mechanism of xanthohumol‐induced apoptosis in MCF‐7 and MCF‐7/ADR cells
The FASEB Journal, 2010 Xanthohumol, the principal prenylated chalcone that only found in the hop plant, Humulus lupulus L., has been shown to possess a variety of pharmacological activities.
Youra Kang +3 more
openaire +1 more source
Differential regulation of specific genes in MCF-7 and the ICI 182780-resistant cell line MCF-7/182R-6 [PDF]
British Journal of Cancer, 1999 To elucidate the mechanisms involved in anti-oestrogen resistance, two human breast cancer cell lines MCF-7 and the ICI 182780-resistant cell line, MCF-7/182R-6, have been compared with regard to oestrogen receptor (ER) expression, ER function, ER regulation, growth requirements and differentially expressed gene products.
Jensen, B L +3 more
openaire +2 more sources
Adıyaman Üniversitesi Sağlık Bilimleri DergisiAim: The aim of this study was to investigate the effects of glutathione (GSH) on chemotherapy-related toxicities in MCF-7 breast cancer cell line treated with paclitaxel (PTX) by cell viability and oxsidative stres parameters.Materials and Methods ...
Gamze Sevri Ekren Aşıcı +4 more
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β-Elemene Reverses Chemoresistance of Breast Cancer via Regulating MDR-Related MicroRNA Expression
Cellular Physiology and Biochemistry, 2014 Background: Multidrug resistance (MDR) directly contributes to the clinical failure of chemotherapy in breast cancer (BCA). β-elemene is a natural antitumor drug from plants. We previously confirmed that MDR could be reversed by β-elemene. In this study,
Jun Zhang +9 more
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Construction of single-chain variable fragment antibodies against MCF-7 breast cancer cells. [PDF]
, 2013 A phage display library of single chain variable fragment (scFv) against MCF-7 breast cancer cells was constructed from C3A8 hybridoma cells. RNA from the C3A8 was isolated, cDNA was constructed, and variable heavy and light immunoglobulin chain gene ...
Ahmad, Zuhaida Asra +6 more
core +1 more source
Cancer Cell International, 2003 Background Human MCF-7 cells have been studied extensively as a model for breast cancer cell growth. Many reports have established that serum-starved MCF-7 cells can be induced to proliferate upon the sole addition of 17β-estradiol (E2).
Steenbergh Paul H +3 more
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Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source