MCF-7 and its Multidrug Resistant Variant MCF-7/ADR Overcome TNF Cytotoxicity through Prevention of Reactive Oxygen Species Accumulation [PDF]
Pharmaceutical Sciences, 2019 Background: Signal transduction of numerous cytokines and growth factors are mediated by reactive oxygen species (ROS). Tumor necrosis factor-α (TNF-α) have stimulated accumulation of ROS in various in vitro studies.
Morteza Ghandadi +4 more
doaj +1 more source
Overexpression of microRNA-16 declines cellular growth, proliferation and induces apoptosis in human breast cancer cells [PDF]
, 2015 MicroRNAs (miRNA) are a large family of small single-stranded RNA molecules found in all multicellular organisms. Early studies have been shown that miRNA are involved in cancer development and progression, and this role can be done by working as an ...
Hafizi, M. +8 more
core +2 more sources
Aberrant N-glycolylneuraminic acid in breast MCF-7 cancer cells and cancer stem cells
Frontiers in Molecular Biosciences, 2022 N-Glycolylneuraminic acid (Neu5Gc) is not normally detected in humans because humans lack the hydroxylase enzyme that converts cytidine-5′-monophosphate-N-acetylneuraminic acid (CMP-Neu5Ac) to CMP-Neu5Gc; thus, any Neu5Gc appearing in the human body is ...
Wenqian Yang +4 more
doaj +1 more source
Effects of silencing Ki-67 gene on doxorubicin resistance of breast cancer MCF-7/DOX cells [PDF]
Waike lilun yu shijian, 2023 Objective To study the effect of Ki-67 gene silencing on doxorubicin (DOX) resistance in breast cancer MCF-7 cells. Methods Liposome transient transfection method and breast cancer MCF-7 cells cultured in vitro were used combined with the transfection of
DONG Jun, CUI Fengming, LIU Jun
doaj +1 more source
Genistein-induced mir-23b expression inhibits the growth of breast cancer cells [PDF]
, 2015 Aim of the study: Genistein, an isoflavonoid, plays roles in the inhibition of protein tyrosine kinase phosphorylation, induction of apoptosis, and cell differentiation in breast cancer.
Avci, C.B. +6 more
core +2 more sources
New 3-Cyano-2-Substituted Pyridines Induce Apoptosis in MCF 7 Breast Cancer Cells
Molecules, 2016 The synthesis of new 3-cyano-2-substituted pyridines bearing various pharmacophores and functionalities at position 2 is described. The synthesized compounds were evaluated for their in vitro anti-cancer activities on five cancer cell lines using 5-FU as
Ahmed Malki +7 more
doaj +1 more source
Expression and Functional of LncRNA XIST in MCF-7 Breast Cancer Cells
Zhongliu Fangzhi Yanjiu, 2019 Objective To investigate the expression and function of lncRNA XIST in MCF-7 breast cancer cells. Methods The expression of XIST in MCF 10A human normal breast epithelial cells and MCF-7 human breast cancer cells were detected by qRT-PCR.
HOU Xia +10 more
doaj +1 more source
The small heat shock protein B8 (HSPB8) modulates proliferation and migration of breast cancer cells [PDF]
, 2017 open12noBreast cancer (BC) is one of the major causes of cancer death in women and is closely related to hormonal dysregulation. Estrogen receptor (ER)-positive BCs are generally treated with anti hormone therapy using antiestrogens or aromatase ...
CARRA, Serena +11 more
core +3 more sources
Cytotoxic Effects of Alchemilla mollis (Buser) Rothm. Extracts on MCF 7 Cell Line
Proceedings, 2017 Alchemilla is a genus of herbaceous perennial plants in the Rosaceae, with the common name Lady’s Mantle. Aerial part of the plant which is used medicinally, traditionally used for skin irritations, wounds, female conditions such as menorrhagia ...
Selen İlgün +2 more
doaj +1 more source
Lewis X antigen mediates adhesion of human breast carcinoma cells to activated endothelium. Possible involvement of the endothelial scavenger receptor C-Type lectin [PDF]
, 2007 Lewis x (Lex, CD15), also known as SSEA-1 (stage specific embryonic antigen-1), is a trisaccharide with the structure Galβ(1–4)Fucα(1–3)GlcNAc, which is expressed on glycoconjugates in human polymorphonuclear granulocytes and various tumors such as colon
A Hittelet +51 more
core +1 more source