Results 21 to 30 of about 114,577 (260)

The molecular mechanism of xanthohumol‐induced apoptosis in MCF‐7 and MCF‐7/ADR cells

The FASEB Journal, 2010
Xanthohumol, the principal prenylated chalcone that only found in the hop plant, Humulus lupulus L., has been shown to possess a variety of pharmacological activities.
Youra Kang, Min‐A Park, Keon‐Wook Kang, Jung‐Ae Kim   +3 more
openaire   +1 more source

Cytotoxic Effects of Alchemilla mollis (Buser) Rothm. Extracts on MCF 7 Cell Line

Proceedings, 2017
Alchemilla is a genus of herbaceous perennial plants in the Rosaceae, with the common name Lady’s Mantle. Aerial part of the plant which is used medicinally, traditionally used for skin irritations, wounds, female conditions such as menorrhagia ...
Selen İlgün, Gökçe Şeker Karatoprak, Müberra Koşar   +2 more
doaj   +1 more source

Differential regulation of specific genes in MCF-7 and the ICI 182780-resistant cell line MCF-7/182R-6 [PDF]

British Journal of Cancer, 1999
To elucidate the mechanisms involved in anti-oestrogen resistance, two human breast cancer cell lines MCF-7 and the ICI 182780-resistant cell line, MCF-7/182R-6, have been compared with regard to oestrogen receptor (ER) expression, ER function, ER regulation, growth requirements and differentially expressed gene products.
Jensen, B L, Skouv, J, Lundholt, B K, Lykkesfeldt, A E   +3 more
openaire   +2 more sources

Comparative analysis of the cytotoxic effect of 7-prenyloxycoumarin compounds and herniarin on MCF-7 cell line [PDF]

Avicenna Journal of Phytomedicine, 2015
Objectives: 7-prenyloxycoumarins are a group of secondary metabolites that are found mainly in plants belonging to the Rutaceae and Umbelliferae families.
Seyed Hadi Mousavi, Atiyeh-Sadat Davari, Mehrdad Iranshahi, Sarvenaz Sabouri-Rad, Zahra Tayarani Najaran   +4 more
doaj  

Nuclear β-catenin and CD44 upregulation characterize invasive cell populations in non-aggressive MCF-7 breast cancer cells

BMC Cancer, 2010
Background In breast cancer cells, the metastatic cell state is strongly correlated to epithelial-to-mesenchymal transition (EMT) and the CD44+/CD24- stem cell phenotype.
Uchino Masahiro, Kojima Hiroko, Wada Kenta, Imada Mika, Onoda Fumitoshi, Satofuka Hiroyuki, Utsugi Takahiko, Murakami Yasufumi   +7 more
doaj   +1 more source

Combination of Doxorubicin and Berberine Generated Synergistic Anticancer Effect on Breast Cancer Cells Through Down-regulation of Nanog and miRNA-21 Gene Expression

Middle East Journal of Cancer, 2020
Background: Our purpose was to investigate the effect of berberine (BER) and doxorubicin (DOX) on the expression of stem cell markers Nanog and microRNA- 21 in MCF-7 cells.
Samia A. Ebeid, Nadia A. Abd El Moneim, Hossam El-Din M. Ghoneim, Sanaa A. El-Benhawy, Samah E. Ismail   +4 more
doaj   +1 more source

A New Chalcone Derivative C49 Reverses Doxorubicin Resistance in MCF-7/DOX Cells by Inhibiting P-Glycoprotein Expression

Frontiers in Pharmacology, 2021
Objective: C49 is a chalcone derivative. The aim of the current study is to illuminate the efficacy of C49 in reversing multidrug resistance (MDR) in MCF-7/DOX cells and its underlying molecular mechanism.Methods: The cytotoxic effects of C49 on MCF-7 ...
Ting Wang, Jingjing Dong, Xu Yuan, Haotian Wen, Linguangjin Wu, Jianwen Liu, Hua Sui, Wanli Deng   +7 more
doaj   +1 more source

Cytotoxic and antioxidant effects of paclitaxel and glutathione combination on breast cancer cell line

Adıyaman Üniversitesi Sağlık Bilimleri Dergisi
Aim: The aim of this study was to investigate the effects of glutathione (GSH) on chemotherapy-related toxicities in MCF-7 breast cancer cell line treated with paclitaxel (PTX) by cell viability and oxsidative stres parameters.Materials and Methods ...
Gamze Sevri Ekren Aşıcı, İrem Bayar, Adem Yavaş, Ayşegül Bildik, Pınar Alkım Ulutaş   +4 more
doaj   +1 more source

β-Elemene Reverses Chemoresistance of Breast Cancer via Regulating MDR-Related MicroRNA Expression

Cellular Physiology and Biochemistry, 2014
Background: Multidrug resistance (MDR) directly contributes to the clinical failure of chemotherapy in breast cancer (BCA). β-elemene is a natural antitumor drug from plants. We previously confirmed that MDR could be reversed by β-elemene. In this study,
Jun Zhang, He da Zhang, Lin Chen, Da Wei Sun, Chang fei Mao, Wei Chen, Jian Zhong Wu, Shan liang Zhong, Jian Hua Zhao, Jin Hai Tang   +9 more
doaj   +1 more source

Cyperotundone combined with adriamycin induces apoptosis in MCF-7 and MCF-7/ADR cancer cells by ROS generation and NRF2/ARE signaling pathway

Scientific Reports, 2023
Breast cancer has become the most prevalent cancer, globally. Adriamycin is a first-line chemotherapeutic agent, however, cancer cells acquire resistance to it, which is one of the most common causes of treatment failure.
Wenna Shao, Xinzhao Wang, Zhaoyun Liu, Xiang Song, Fukai Wang, Xiaoyu Liu, Zhiyong Yu   +6 more
doaj   +1 more source