Results 21 to 30 of about 7,687,713 (299)
Aberrant N-glycolylneuraminic acid in breast MCF-7 cancer cells and cancer stem cells
Frontiers in Molecular Biosciences, 2022 N-Glycolylneuraminic acid (Neu5Gc) is not normally detected in humans because humans lack the hydroxylase enzyme that converts cytidine-5′-monophosphate-N-acetylneuraminic acid (CMP-Neu5Ac) to CMP-Neu5Gc; thus, any Neu5Gc appearing in the human body is ...
Wenqian Yang +4 more
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New 3-Cyano-2-Substituted Pyridines Induce Apoptosis in MCF 7 Breast Cancer Cells
Molecules, 2016 The synthesis of new 3-cyano-2-substituted pyridines bearing various pharmacophores and functionalities at position 2 is described. The synthesized compounds were evaluated for their in vitro anti-cancer activities on five cancer cell lines using 5-FU as
Ahmed Malki +7 more
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Assessment of the cytotoxicity and genotoxicity of homosalate in MCF‐7
Journal of Cosmetic Dermatology, 2019 AbstractBackgroundUV filters should be determined a strict toxicological safety prior to approval. Homosalate (HMS) is one of the most widely used organic UV filter. HMS accumulates in aquatic biota ecosystems and humans through the food chain; therefore, it is important to consider the effects on health and know its mechanisms of action.AimsThe study ...
Selma Yazar, Simge Kara Ertekin
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Increased STAT1 signaling in endocrine-resistant breast cancer [PDF]
, 2014 Funding: China Scholarship Council, University of Edinburgh, Scottish Funding Council and Breakthrough Breast Cancer.Proteomic profiling of the estrogen/tamoxifen-sensitive MCF-7 cell line and its partially sensitive (MCF-7/LCC1) and fully resistant (MCF-
Thomas Jeremy S. +32 more
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Effects of silencing Ki-67 gene on doxorubicin resistance of breast cancer MCF-7/DOX cells [PDF]
Waike lilun yu shijian, 2023 Objective To study the effect of Ki-67 gene silencing on doxorubicin (DOX) resistance in breast cancer MCF-7 cells. Methods Liposome transient transfection method and breast cancer MCF-7 cells cultured in vitro were used combined with the transfection of
DONG Jun, CUI Fengming, LIU Jun
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Cytotoxic Effects of Alchemilla mollis (Buser) Rothm. Extracts on MCF 7 Cell Line
Proceedings, 2017 Alchemilla is a genus of herbaceous perennial plants in the Rosaceae, with the common name Lady’s Mantle. Aerial part of the plant which is used medicinally, traditionally used for skin irritations, wounds, female conditions such as menorrhagia ...
Selen İlgün +2 more
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Molecules, 2016 Despite progressive research being done on drug therapy to treat breast cancer, the number of patients succumbing to the disease is still a major issue. Combinatorial treatment using different drugs and herbs to treat cancer patients is of major interest
Muhammad Yusran Abdul Aziz +9 more
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The molecular mechanism of xanthohumol‐induced apoptosis in MCF‐7 and MCF‐7/ADR cells
The FASEB Journal, 2010 Xanthohumol, the principal prenylated chalcone that only found in the hop plant, Humulus lupulus L., has been shown to possess a variety of pharmacological activities.
Youra Kang +3 more
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Differential regulation of specific genes in MCF-7 and the ICI 182780-resistant cell line MCF-7/182R-6 [PDF]
British Journal of Cancer, 1999 To elucidate the mechanisms involved in anti-oestrogen resistance, two human breast cancer cell lines MCF-7 and the ICI 182780-resistant cell line, MCF-7/182R-6, have been compared with regard to oestrogen receptor (ER) expression, ER function, ER regulation, growth requirements and differentially expressed gene products.
Jensen, B L +3 more
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Comparative analysis of the cytotoxic effect of 7-prenyloxycoumarin compounds and herniarin on MCF-7 cell line [PDF]
Avicenna Journal of Phytomedicine, 2015 Objectives: 7-prenyloxycoumarins are a group of secondary metabolites that are found mainly in plants belonging to the Rutaceae and Umbelliferae families.
Seyed Hadi Mousavi +4 more
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