Results 11 to 20 of about 114,577 (260)
Tamoxifen induces ferroptosis in MCF-7 organoid
Journal of Cancer Research and Therapeutics, 2023 Background: Breast cancer is the most common female malignant tumor type globally. The occurrence and development of breast cancer involve ferroptosis, which is closely related to its treatment.
Lei, Ye +6 more
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Indonesian Journal of Biotechnology, 2012 The long-term exposure of doxorubicin (Dox) causes enhancement in MDR1 expression that leads to breast cancer cell resistance. This protein become a serious problem in cancer treatment and also well-known as negative prognostic factor in breast cancer ...
Nunuk Aries Nurulita +3 more
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Overexpression of TMEM47 Induces Tamoxifen Resistance in Human Breast Cancer Cells
Technology in Cancer Research & Treatment, 2021 Background: Tamoxifen (TAM) is the eminent first-line drug for endocrine therapy of hormone receptor positive premenopausal breast cancer and reduces the risk of recurrence by ∼50%.
Xin Men +6 more
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MCF-7 and its Multidrug Resistant Variant MCF-7/ADR Overcome TNF Cytotoxicity through Prevention of Reactive Oxygen Species Accumulation [PDF]
Pharmaceutical Sciences, 2019 Background: Signal transduction of numerous cytokines and growth factors are mediated by reactive oxygen species (ROS). Tumor necrosis factor-α (TNF-α) have stimulated accumulation of ROS in various in vitro studies.
Morteza Ghandadi +4 more
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New 3-Cyano-2-Substituted Pyridines Induce Apoptosis in MCF 7 Breast Cancer Cells
Molecules, 2016 The synthesis of new 3-cyano-2-substituted pyridines bearing various pharmacophores and functionalities at position 2 is described. The synthesized compounds were evaluated for their in vitro anti-cancer activities on five cancer cell lines using 5-FU as
Ahmed Malki +7 more
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Aberrant N-glycolylneuraminic acid in breast MCF-7 cancer cells and cancer stem cells
Frontiers in Molecular Biosciences, 2022 N-Glycolylneuraminic acid (Neu5Gc) is not normally detected in humans because humans lack the hydroxylase enzyme that converts cytidine-5′-monophosphate-N-acetylneuraminic acid (CMP-Neu5Ac) to CMP-Neu5Gc; thus, any Neu5Gc appearing in the human body is ...
Wenqian Yang +4 more
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Expression and Functional of LncRNA XIST in MCF-7 Breast Cancer Cells
Zhongliu Fangzhi Yanjiu, 2019 Objective To investigate the expression and function of lncRNA XIST in MCF-7 breast cancer cells. Methods The expression of XIST in MCF 10A human normal breast epithelial cells and MCF-7 human breast cancer cells were detected by qRT-PCR.
HOU Xia +10 more
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Effects of silencing Ki-67 gene on doxorubicin resistance of breast cancer MCF-7/DOX cells [PDF]
Waike lilun yu shijian, 2023 Objective To study the effect of Ki-67 gene silencing on doxorubicin (DOX) resistance in breast cancer MCF-7 cells. Methods Liposome transient transfection method and breast cancer MCF-7 cells cultured in vitro were used combined with the transfection of
DONG Jun, CUI Fengming, LIU Jun
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Assessment of the cytotoxicity and genotoxicity of homosalate in MCF‐7
Journal of Cosmetic Dermatology, 2019 AbstractBackgroundUV filters should be determined a strict toxicological safety prior to approval. Homosalate (HMS) is one of the most widely used organic UV filter. HMS accumulates in aquatic biota ecosystems and humans through the food chain; therefore, it is important to consider the effects on health and know its mechanisms of action.AimsThe study ...
Selma Yazar, Simge Kara Ertekin
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Molecules, 2016 Despite progressive research being done on drug therapy to treat breast cancer, the number of patients succumbing to the disease is still a major issue. Combinatorial treatment using different drugs and herbs to treat cancer patients is of major interest
Muhammad Yusran Abdul Aziz +9 more
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