Results 11 to 20 of about 7,687,713 (299)

Invasive and metastatic properties of MCF‐7 cells and ras^H‐transfected MCF‐7 cell lines

International Journal of Cancer, 1992
AbstractIn vitro invasion and in vivo metastasis assays were performed with a panel of MCF‐7 cells transfected with isogenic constructs of mutated rasH genes. Both increased levels of rasH expression and rasH oncogene activation increased activity of derivative cell lines in in vitro invasion assays.
Gelmann, Edward P., Thompson, Erik W., Sommers, Connie L.   +2 more
openaire   +4 more sources

Steroid metabolism in the hormone dependent MCF-7 human breast carcinoma cell line and its two hormone resistant subpopulations MCF-7/LCC1 and MCF-7/LCC2.

The Journal of steroid biochemistry and molecular biology, 1998
Androgen and estrogen metabolism was investigated in the hormone-dependent human breast cancer cell line MCF-7 and its two hormone-resistant sublines MCF-7/LCC1 and MCF-7/LCC2. Using the product isolation method, the activity of aromatase, 5alpha-reductase, 3alpha/beta-hydroxysteroid oxidoreductase and 17beta-hydroxysteroid oxidoreductase were ...
Jørgensen, L, Brünner, N, Spang-Thomsen, M, James, M R, Clarke, R, Dombernowsky, P, Svenstrup, B   +6 more
core   +4 more sources

Comparison of Short-Term Estrogenicity Tests for Identification of Hormone-Disrupting Chemicals [PDF]

, 1999
The aim of this study was to compare results obtained by eight different short-term assays of estrogenlike actions of chemicals conducted in 10 different laboratories in five countries. Twenty chemicals were selected to represent direct-acting estrogens,
Andersson, AM, McLachlan, J, Arnold, SF, Skakkeboek, NE, Andersen, HR, Pedersen, KL, Korsgaard, B, Le Guevel, R, Grandjean, P, Autrup, H, Leffers, H, Barfoed, N, Moller, A, Hummel, R, Oles-Karasko, A, Gissel, B, Beresford, NA, Perez, P, Bjerregaard, P, Thorpe, SM, Soto, AM, Olea, N, Sumpter, JP, Nielsen, JB, Pakdel, F, Christiansen, LB, Jorgensen, EB, Sonnenschein, C   +27 more
core   +7 more sources

Glycosaminoglycans Targeted by Colchicine in MCF-7 Cells. [PDF]

Pharmaceutics
Background: Breast cancer is the most common cancer diagnosis and the second leading cause of cancer-related death in women. Breast cancer is a major health burden worldwide. Advances in breast cancer detection and treatment have contributed to improving the rate of survival, although mortality rates remain significantly high.
Czarnecka-Czapczyńska M, Przygórzewska A, Dynarowicz K, Bartusik-Aebisher D, Aebisher D, Kawczyk-Krupka A.   +5 more
europepmc   +5 more sources

Monitoring cell cycle distributions in MCF-7 cells using near-field photothermal microspectroscopy. [PDF]

, 2005
Microspectroscopic techniques such as Fourier transform infrared (FTIR) have played an important role in "fingerprinting" the biochemical composition of cellular components.
Hewitt, Rebecca, Martin, Francis L., German, Matthew J., Pollock, Hubert M., Hammiche, Azzadine   +4 more
core   +5 more sources

Annexin-A5 Overexpression Increases Sensitivity of MCF-7 and MCF-7/ADR Cells to Epirubicin

Avicenna Journal of Medical Biotechnology, 2023
Background: Multi-drug resistance is an important challenge in the chemotherapy of cancer. The role of annexin A5 (ANXA5) in the biology of cancer has been the focus of many studies. Breast Cancer (BC) is frequent cancer in women with high morbidity and mortality rate.
Ghasemi, Mahshad, Reiazi, Niloofar, Behzad-Behbahani, Abbas, Takhshid, Mohammad Ali   +3 more
openaire   +2 more sources

Adipose-Derived Stem Cell Features and MCF-7 [PDF]

Cells, 2021
Human adipose tissue-derived stem cells (hADSCs) are highly suitable for regeneration therapies being easily collected and propagated in vitro. The effects of different external factors and culturing conditions are able to affect hADSC proliferation, senescence, differentiation, and migration, even at the molecular level.
Giuseppe Garroni, Francesca Balzano, Sara Cruciani, Renzo Pala, Donatella Coradduzza, Emanuela Azara, Emanuela Bellu, Maria Laura Cossu, Giorgio C. Ginesu, Ciriaco Carru, Carlo Ventura, Margherita Maioli   +11 more
openaire   +7 more sources

Tamoxifen induces ferroptosis in MCF-7 organoid

Journal of Cancer Research and Therapeutics, 2023
Background: Breast cancer is the most common female malignant tumor type globally. The occurrence and development of breast cancer involve ferroptosis, which is closely related to its treatment.
Lei, Ye, Fei, Zhong, Shishen, Sun, Xiaowei, Ou, Jie, Yuan, Jintao, Zhu, Zhiqiang, Zeng   +6 more
openaire   +2 more sources

Confocal Raman data analysis enables identifying apoptosis of MCF-7 cells caused by anticancer drug paclitaxel [PDF]

, 2013
Confocal Raman microscopy is a noninvasive, label-free imaging technique used to study apoptosis of live MCF-7 cells. The images are based on Raman spectra of cells components, and their apoptosis is monitored through diffusion of cytochrome c in ...
Salehi, Hamideh, Collard Dutilleul, Pierre-Yves, Ramakrishnan, Satish, Middendorp, Elodie, Panayotov, Ivan, Dutilleul, Pierre-Yves Collart, Gergely, Csilla, Cuisinier, Frédéric J. G., Végh, Attila Gergely   +8 more
core   +1 more source

Role of insulin-like growth factor binding protein-3 in 1, 25-dihydroxyvitamin-d 3 -induced breast cancer cell apoptosis. [PDF]

, 2013
Insulin-like growth factor I (IGF-I) is implicated in breast cancer development and 1, 25-dihydroxyvitamin D3 (1, 25-D3) has been shown to attenuate prosurvival effects of IGF-I on breast cancer cells.
Brosseau, C, Colston, KW, G. Pirianov, K. W. Colston, C. Brosseau, Pirianov, G   +5 more
core   +1 more source