5-(carbamoylmethylene)-oxazolidin-2-ones as a promising class of heterocycles inducing apoptosis triggered by increased ROS levels and mitochondrial dysfunction in breast and cervical cancer [PDF]
Oxazolidinones are antibiotics that inhibit protein synthesis by binding the 50S ribosomal subunit. Recently, numerous worldwide researches focused on their properties and possible involvement in cancer therapy have been conducted.
Armentano, B +10 more
core +2 more sources
Despite progressive research being done on drug therapy to treat breast cancer, the number of patients succumbing to the disease is still a major issue. Combinatorial treatment using different drugs and herbs to treat cancer patients is of major interest
Muhammad Yusran Abdul Aziz +9 more
doaj +1 more source
Background: Our purpose was to investigate the effect of berberine (BER) and doxorubicin (DOX) on the expression of stem cell markers Nanog and microRNA- 21 in MCF-7 cells.
Samia A. Ebeid +4 more
doaj +1 more source
Confocal Raman data analysis enables identifying apoptosis of MCF-7 cells caused by anticancer drug paclitaxel [PDF]
Confocal Raman microscopy is a noninvasive, label-free imaging technique used to study apoptosis of live MCF-7 cells. The images are based on Raman spectra of cells components, and their apoptosis is monitored through diffusion of cytochrome c in ...
Attila-Gergely Vegh +7 more
core +2 more sources
Elevated expression of long intergenic non-coding RNA HOTAIR in a basal-like variant of MCF-7 breast cancer cells [PDF]
Epigenetic regulation of gene expression is critical to phenotypic maintenance and transition of human breast cancer cells. HOX antisense intergenic RNA (HOTAIR) is a long intergenic non-coding RNA that epigenetically represses gene expression via ...
Burow, Matthew E. +14 more
core +1 more source
A systematic literature review: the effect of date palms (phoenix dactylifera) toward breast cancer MCF-7 cell line. [PDF]
Breast cancer is most significant diagnosed cancer in women that approximately 2.1 millions women were diagnosed with breast cancer and caused 627,000 deaths worldwide in 2018 based on Press Release 2018 from International Agency for Research on Cancer ...
Abdullah, Teo Wee Siang@Aariz Daniel Teo +3 more
core
Variable Response to Chemotherapeutics by a Subpopulation of MCF-7 Breast Cancer Cells [PDF]
Several different morphologies can be observed in a population of MCF-7 breast cancer cells, but the typical epithelial morphology vastly predominates. After treatment with the chemotherapeutic doxorubicin, the proportion of abnormal morphologies greatly
Dorland, Julie
core +1 more source
Comparative analysis of the cytotoxic effect of 7-prenyloxycoumarin compounds and herniarin on MCF-7 cell line [PDF]
Objectives: 7-prenyloxycoumarins are a group of secondary metabolites that are found mainly in plants belonging to the Rutaceae and Umbelliferae families.
Seyed Hadi Mousavi +4 more
doaj
The role of a new CD44st in increasing the invasion capability of the human breast cancer cell line MCF-7 [PDF]
Background CD44, a hyaluronan (HA) receptor, is a multistructural and multifunctional cell surface molecule involved in cell proliferation, cell differentiation, cell migration, angiogenesis, presentation of cytokines, chemokines and growth ...
Xin Jian Fang +3 more
core +2 more sources
Objective: C49 is a chalcone derivative. The aim of the current study is to illuminate the efficacy of C49 in reversing multidrug resistance (MDR) in MCF-7/DOX cells and its underlying molecular mechanism.Methods: The cytotoxic effects of C49 on MCF-7 ...
Ting Wang +7 more
doaj +1 more source

