Results 31 to 40 of about 7,687,713 (299)

Nuclear β-catenin and CD44 upregulation characterize invasive cell populations in non-aggressive MCF-7 breast cancer cells

BMC Cancer, 2010
Background In breast cancer cells, the metastatic cell state is strongly correlated to epithelial-to-mesenchymal transition (EMT) and the CD44+/CD24- stem cell phenotype.
Uchino Masahiro, Kojima Hiroko, Wada Kenta, Imada Mika, Onoda Fumitoshi, Satofuka Hiroyuki, Utsugi Takahiko, Murakami Yasufumi   +7 more
doaj   +1 more source

Combination of Doxorubicin and Berberine Generated Synergistic Anticancer Effect on Breast Cancer Cells Through Down-regulation of Nanog and miRNA-21 Gene Expression

Middle East Journal of Cancer, 2020
Background: Our purpose was to investigate the effect of berberine (BER) and doxorubicin (DOX) on the expression of stem cell markers Nanog and microRNA- 21 in MCF-7 cells.
Samia A. Ebeid, Nadia A. Abd El Moneim, Hossam El-Din M. Ghoneim, Sanaa A. El-Benhawy, Samah E. Ismail   +4 more
doaj   +1 more source

MCF-7 cell line Exposed to Spebrutinib

, 2019
MCF-7 cell line Exposed to ...
zaid.alobaidi@uokerbala.edu.iq zaid.alobaidi@uokerbala.edu.iq (6703289)
core   +1 more source

A New Chalcone Derivative C49 Reverses Doxorubicin Resistance in MCF-7/DOX Cells by Inhibiting P-Glycoprotein Expression

Frontiers in Pharmacology, 2021
Objective: C49 is a chalcone derivative. The aim of the current study is to illuminate the efficacy of C49 in reversing multidrug resistance (MDR) in MCF-7/DOX cells and its underlying molecular mechanism.Methods: The cytotoxic effects of C49 on MCF-7 ...
Ting Wang, Jingjing Dong, Xu Yuan, Haotian Wen, Linguangjin Wu, Jianwen Liu, Hua Sui, Wanli Deng   +7 more
doaj   +1 more source

Upregulation of autophagy by Ginsenoside Rg2 in MCF-7 cells [PDF]

Animal Cells and Systems, 2018
Autophagy is a major intracellular degradation process that plays an important role in cell survival, stress responses, nutrient sensing and development. Our previous studies have shown that Rg2, a triterpenoid saponin contained in ginseng, protects cells against UVB-induced genotoxicity by increasing DNA repair, in possible association with modulation
Chung, Yuheon, Jeong, Seula, Choi, Hyun S., Ro, Seungil, Lee, Jung S., Park, Jong K.   +5 more
openaire   +4 more sources

MCF-7 Cell line Exposed to compound 2a.

, 2019
MCF-7 Cell line Exposed to compound ...
zaid.alobaidi@uokerbala.edu.iq zaid.alobaidi@uokerbala.edu.iq (6703289)
core   +1 more source

Cytotoxic and antioxidant effects of paclitaxel and glutathione combination on breast cancer cell line

Adıyaman Üniversitesi Sağlık Bilimleri Dergisi
Aim: The aim of this study was to investigate the effects of glutathione (GSH) on chemotherapy-related toxicities in MCF-7 breast cancer cell line treated with paclitaxel (PTX) by cell viability and oxsidative stres parameters.Materials and Methods ...
Gamze Sevri Ekren Aşıcı, İrem Bayar, Adem Yavaş, Ayşegül Bildik, Pınar Alkım Ulutaş   +4 more
doaj   +1 more source

β-Elemene Reverses Chemoresistance of Breast Cancer via Regulating MDR-Related MicroRNA Expression

Cellular Physiology and Biochemistry, 2014
Background: Multidrug resistance (MDR) directly contributes to the clinical failure of chemotherapy in breast cancer (BCA). β-elemene is a natural antitumor drug from plants. We previously confirmed that MDR could be reversed by β-elemene. In this study,
Jun Zhang, He da Zhang, Lin Chen, Da Wei Sun, Chang fei Mao, Wei Chen, Jian Zhong Wu, Shan liang Zhong, Jian Hua Zhao, Jin Hai Tang   +9 more
doaj   +1 more source

Cyperotundone combined with adriamycin induces apoptosis in MCF-7 and MCF-7/ADR cancer cells by ROS generation and NRF2/ARE signaling pathway

Scientific Reports, 2023
Breast cancer has become the most prevalent cancer, globally. Adriamycin is a first-line chemotherapeutic agent, however, cancer cells acquire resistance to it, which is one of the most common causes of treatment failure.
Wenna Shao, Xinzhao Wang, Zhaoyun Liu, Xiang Song, Fukai Wang, Xiaoyu Liu, Zhiyong Yu   +6 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source