Results 1 to 10 of about 7,687,713 (299)
ROCK inhibition activates MCF-7 cells. [PDF]
PLoS ONE, 2014 Dormant carcinoma cancer cells showing epithelial characteristics can be activated to dissipate into the surrounding tissue or organs through epithelial-mesenchymal transition (EMT).
Seungwon Yang, Hyun-Man Kim
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Utility of Activated Nitriles in the Synthesis of some New Pyridine and Fused Pyridine Derivatives with Anticancer Activity [PDF]
Journal of Advanced Pharmacy Research, 2021 Objective: This study aimed synthesis of pyridine and fused pyridine derivatives based on the importance of these heterocycles as anticancer. Method: Novel pyridine and fused pyridine derivatives 3-35 were synthesized through different chemical reactions.
Aisha Helali, Marwa Sarg, Mona Elzoghbi
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In vitro cytotoxic effect of stigmasterol derivatives against breast cancer cells
BMC Complementary Medicine and Therapies, 2023 Background Stigmasterol is an unsaturated phytosterol that belong to the class of tetracyclic steroids abundant in Rhoicissus tridentata. Stigmasterol is an important constituent since it has shown impressive pharmacological effects such as anti ...
Nondumiso Premilla Dube +8 more
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Molecules, 2020 A bottom-up approach for synthesizing silver nanoparticles (AgNPs-GA) phytomediated by Garcinia atroviridis leaf extract is described. Under optimized conditions, the AgNPs-GA were synthesized at a concentration of 0.1 M silver salt and 10% (w/v) leaf ...
Nurul Izzati Zulkifli +7 more
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Potential Therapeutic Effect of Natural Killer Cells on Doxorubicin-Resistant Breast Cancer Cells In Vitro. [PDF]
PLoS ONE, 2015 The aim of this study was to explore the therapeutic effect of natural killer (NK) cells on human doxorubicin-sensitive and resistant breast adenocarcinoma.Human doxorubicin-sensitive and resistant breast cancer cell lines (MCF-7 and MCF-7/ADR) were ...
Mi-Hye Hwang +6 more
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Downregulation of Choline Kinase-Alpha Enhances Autophagy in Tamoxifen-Resistant Breast Cancer Cells. [PDF]
PLoS ONE, 2015 Choline kinase-α (Chk-α) and autophagy have gained much attention, as they relate to the drug-resistance of breast cancer. Here, we explored the potential connection between Chk-α and autophagy in the mechanisms driving to tamoxifen (TAM) resistance, in ...
Hoe Suk Kim +6 more
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Indonesian Journal of Biotechnology, 2012 The long-term exposure of doxorubicin (Dox) causes enhancement in MDR1 expression that leads to breast cancer cell resistance. This protein become a serious problem in cancer treatment and also well-known as negative prognostic factor in breast cancer ...
Nunuk Aries Nurulita +3 more
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Overexpression of TMEM47 Induces Tamoxifen Resistance in Human Breast Cancer Cells
Technology in Cancer Research & Treatment, 2021 Background: Tamoxifen (TAM) is the eminent first-line drug for endocrine therapy of hormone receptor positive premenopausal breast cancer and reduces the risk of recurrence by ∼50%.
Xin Men +6 more
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MCF-7 and its Multidrug Resistant Variant MCF-7/ADR Overcome TNF Cytotoxicity through Prevention of Reactive Oxygen Species Accumulation [PDF]
Pharmaceutical Sciences, 2019 Background: Signal transduction of numerous cytokines and growth factors are mediated by reactive oxygen species (ROS). Tumor necrosis factor-α (TNF-α) have stimulated accumulation of ROS in various in vitro studies.
Morteza Ghandadi +4 more
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Expression and Functional of LncRNA XIST in MCF-7 Breast Cancer Cells
Zhongliu Fangzhi Yanjiu, 2019 Objective To investigate the expression and function of lncRNA XIST in MCF-7 breast cancer cells. Methods The expression of XIST in MCF 10A human normal breast epithelial cells and MCF-7 human breast cancer cells were detected by qRT-PCR.
HOU Xia +10 more
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