Results 1 to 10 of about 114,577 (260)

Glycosaminoglycans Targeted by Colchicine in MCF-7 Cells. [PDF]

Pharmaceutics
Background: Breast cancer is the most common cancer diagnosis and the second leading cause of cancer-related death in women. Breast cancer is a major health burden worldwide. Advances in breast cancer detection and treatment have contributed to improving the rate of survival, although mortality rates remain significantly high.
Czarnecka-Czapczyńska M, Przygórzewska A, Dynarowicz K, Bartusik-Aebisher D, Aebisher D, Kawczyk-Krupka A.   +5 more
europepmc   +5 more sources

ROCK inhibition activates MCF-7 cells. [PDF]

PLoS ONE, 2014
Dormant carcinoma cancer cells showing epithelial characteristics can be activated to dissipate into the surrounding tissue or organs through epithelial-mesenchymal transition (EMT).
Seungwon Yang, Hyun-Man Kim
doaj   +4 more sources

Ferroptosis Suppressor Protein 1 (FSP1)-CoQ10-NADPH-Axis Is Responsible for Erastin Resistance in MCF-7 Breast Cancer Cells [PDF]

Antioxidants
Ferroptosis has emerged as a promising therapeutic strategy for drug-resistant cancers; however, the molecular mechanisms governing ferroptosis susceptibility in breast cancer remain poorly defined.
Brian B. Silver, Carri Murphy, Erik J. Tokar, Birandra K. Sinha   +3 more
doaj   +2 more sources

Utility of Activated Nitriles in the Synthesis of some New Pyridine and Fused Pyridine Derivatives with Anticancer Activity [PDF]

Journal of Advanced Pharmacy Research, 2021
Objective: This study aimed synthesis of pyridine and fused pyridine derivatives based on the importance of these heterocycles as anticancer. Method: Novel pyridine and fused pyridine derivatives 3-35 were synthesized through different chemical reactions.
Aisha Helali, Marwa Sarg, Mona Elzoghbi
doaj   +1 more source

Annexin-A5 Overexpression Increases Sensitivity of MCF-7 and MCF-7/ADR Cells to Epirubicin

Avicenna Journal of Medical Biotechnology, 2023
Background: Multi-drug resistance is an important challenge in the chemotherapy of cancer. The role of annexin A5 (ANXA5) in the biology of cancer has been the focus of many studies. Breast Cancer (BC) is frequent cancer in women with high morbidity and mortality rate.
Ghasemi, Mahshad, Reiazi, Niloofar, Behzad-Behbahani, Abbas, Takhshid, Mohammad Ali   +3 more
openaire   +2 more sources

In vitro cytotoxic effect of stigmasterol derivatives against breast cancer cells

BMC Complementary Medicine and Therapies, 2023
Background Stigmasterol is an unsaturated phytosterol that belong to the class of tetracyclic steroids abundant in Rhoicissus tridentata. Stigmasterol is an important constituent since it has shown impressive pharmacological effects such as anti ...
Nondumiso Premilla Dube, Vuyelwa Jacqueline Tembu, Getrude R Nyemba, Candace Davison, Goitsemodimo Herckious Rakodi, Douglas Kemboi, Jo-Anne de la Mare, Xavier Siwe-Noundou, Amanda-Lee Ezra Manicum   +8 more
doaj   +1 more source

Adipose-Derived Stem Cell Features and MCF-7 [PDF]

Cells, 2021
Human adipose tissue-derived stem cells (hADSCs) are highly suitable for regeneration therapies being easily collected and propagated in vitro. The effects of different external factors and culturing conditions are able to affect hADSC proliferation, senescence, differentiation, and migration, even at the molecular level.
Giuseppe Garroni, Francesca Balzano, Sara Cruciani, Renzo Pala, Donatella Coradduzza, Emanuela Azara, Emanuela Bellu, Maria Laura Cossu, Giorgio C. Ginesu, Ciriaco Carru, Carlo Ventura, Margherita Maioli   +11 more
openaire   +7 more sources

A Bottom-Up Synthesis Approach to Silver Nanoparticles Induces Anti-Proliferative and Apoptotic Activities Against MCF-7, MCF-7/TAMR-1 and MCF-10A Human Breast Cell Lines

Molecules, 2020
A bottom-up approach for synthesizing silver nanoparticles (AgNPs-GA) phytomediated by Garcinia atroviridis leaf extract is described. Under optimized conditions, the AgNPs-GA were synthesized at a concentration of 0.1 M silver salt and 10% (w/v) leaf ...
Nurul Izzati Zulkifli, Musthahimah Muhamad, Nur Nadhirah Mohamad Zain, Wen-Nee Tan, Noorfatimah Yahaya, Yazmin Bustami, Azlan Abdul Aziz, Nik Nur Syazni Nik Mohamed Kamal   +7 more
doaj   +1 more source

Potential Therapeutic Effect of Natural Killer Cells on Doxorubicin-Resistant Breast Cancer Cells In Vitro. [PDF]

PLoS ONE, 2015
The aim of this study was to explore the therapeutic effect of natural killer (NK) cells on human doxorubicin-sensitive and resistant breast adenocarcinoma.Human doxorubicin-sensitive and resistant breast cancer cell lines (MCF-7 and MCF-7/ADR) were ...
Mi-Hye Hwang, Xiu Juan Li, Jung Eun Kim, Shin Young Jeong, Sang-Woo Lee, Jaetae Lee, Byeong-Cheol Ahn   +6 more
doaj   +1 more source

Downregulation of Choline Kinase-Alpha Enhances Autophagy in Tamoxifen-Resistant Breast Cancer Cells. [PDF]

PLoS ONE, 2015
Choline kinase-α (Chk-α) and autophagy have gained much attention, as they relate to the drug-resistance of breast cancer. Here, we explored the potential connection between Chk-α and autophagy in the mechanisms driving to tamoxifen (TAM) resistance, in ...
Hoe Suk Kim, Lianji Tian, Minji Jung, Sul Ki Choi, Yujin Sun, Hyeonjin Kim, Woo Kyung Moon   +6 more
doaj   +1 more source