Results 1 to 10 of about 106,995 (260)
ROCK inhibition activates MCF-7 cells. [PDF]
PLoS ONE, 2014 Dormant carcinoma cancer cells showing epithelial characteristics can be activated to dissipate into the surrounding tissue or organs through epithelial-mesenchymal transition (EMT).
Seungwon Yang, Hyun-Man Kim
doaj +4 more sources
Asian Pacific Journal of Tropical Biomedicine, 2014 Objective: To evaluate of hesperidin to overcome resistance of doxorubicin in MCF-7 resistant doxorubicin cells (MCF-7/Dox) in cytotoxicity apoptosis and P-glycoprotein (Pgp) expression in combination with doxorubicin.
Rifki Febriansah +5 more
doaj +3 more sources
Effects of silencing Ki-67 gene on doxorubicin resistance of breast cancer MCF-7/DOX cells [PDF]
Waike lilun yu shijian, 2023 Objective To study the effect of Ki-67 gene silencing on doxorubicin (DOX) resistance in breast cancer MCF-7 cells. Methods Liposome transient transfection method and breast cancer MCF-7 cells cultured in vitro were used combined with the transfection of
DONG Jun, CUI Fengming, LIU Jun
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Potential Therapeutic Effect of Natural Killer Cells on Doxorubicin-Resistant Breast Cancer Cells In Vitro. [PDF]
PLoS ONE, 2015 The aim of this study was to explore the therapeutic effect of natural killer (NK) cells on human doxorubicin-sensitive and resistant breast adenocarcinoma.Human doxorubicin-sensitive and resistant breast cancer cell lines (MCF-7 and MCF-7/ADR) were ...
Mi-Hye Hwang +6 more
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Downregulation of Choline Kinase-Alpha Enhances Autophagy in Tamoxifen-Resistant Breast Cancer Cells. [PDF]
PLoS ONE, 2015 Choline kinase-α (Chk-α) and autophagy have gained much attention, as they relate to the drug-resistance of breast cancer. Here, we explored the potential connection between Chk-α and autophagy in the mechanisms driving to tamoxifen (TAM) resistance, in ...
Hoe Suk Kim +6 more
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Archives of Medical Science, 2023 Introduction This study probes the mechanism of the PARP9/PI3K/AKT/PD-L1 axis in the chemoresistance and immune escape of breast cancer cells. Material and methods The expression of related genes was detected in MCF-7/FUL cells.
Tao Hong +3 more
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Overexpression of TMEM47 Induces Tamoxifen Resistance in Human Breast Cancer Cells
Technology in Cancer Research & Treatment, 2021 Background: Tamoxifen (TAM) is the eminent first-line drug for endocrine therapy of hormone receptor positive premenopausal breast cancer and reduces the risk of recurrence by ∼50%.
Xin Men +6 more
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Comparative proteomics study of proteins involved in induction of higher rates of cell death in mitoxantrone-resistant breast cancer cells MCF-7/MX exposed to TNF-α [PDF]
Iranian Journal of Basic Medical Sciences, 2020 Objective(s): Resistance to medications is one of the main complications in chemotherapy of cancer. It has been shown that some multidrug resistant cancer cells indicate more sensitivity against cytotoxic effects of TNF-α compared to their parental cells.
saeed Norouzi +5 more
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Frontiers in Pharmacology, 2021 Objective: C49 is a chalcone derivative. The aim of the current study is to illuminate the efficacy of C49 in reversing multidrug resistance (MDR) in MCF-7/DOX cells and its underlying molecular mechanism.Methods: The cytotoxic effects of C49 on MCF-7 ...
Ting Wang +7 more
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Expression and Functional of LncRNA XIST in MCF-7 Breast Cancer Cells
Zhongliu Fangzhi Yanjiu, 2019 Objective To investigate the expression and function of lncRNA XIST in MCF-7 breast cancer cells. Methods The expression of XIST in MCF 10A human normal breast epithelial cells and MCF-7 human breast cancer cells were detected by qRT-PCR.
HOU Xia +10 more
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