Results 81 to 90 of about 124,045 (313)
Involvement of Cox-2 in the metastatic potential of chemotherapy-resistant breast cancer cells
BMC Cancer, 2011 Background A major problem with the use of current chemotherapy regimens for several cancers, including breast cancer, is development of intrinsic or acquired drug resistance, which results in disease recurrence and metastasis.
Choi Changsun +6 more
doaj +1 more source
Transcriptomic Changes in Cisplatin-Resistant MCF-7 Cells
International Journal of Molecular SciencesBreast cancer is a leading cause of cancer-related deaths among women. Cisplatin is used for treatment, but the development of resistance in cancer cells is a significant concern. This study aimed to investigate changes in the transcriptomes of cisplatin-resistant MCF7 cells.
Araceli Ruiz-Silvestre +8 more
openaire +2 more sources
Rapid Microfluidic Drug Sensitivity Testing Within 5 Days Using Minimal Clinical Tumor Samples
Advanced Science, EarlyView.This study develops the air‐punched fabrication approach for nanoliter‐scale microcavity arrays with ultra‐smooth microcavity surfaces, with which rapid formation and 3D culture of tumor cell spheroids from small numbers of cell samples, as well as high‐throughput drug sensitivity testing can be achieved within 5 days.
Yi‐Xue Chen +11 more
wiley +1 more source
Cell Transplantation, 2015 Although emerging evidence links mesenchymal stem cells (MSCs) with cancer metastasis, the underlying mechanisms are poorly understood. In the present study, we found that human umbilical cord-derived MSCs (UC-MSCs) promoted MCF-7 cell migration in vitro
Fengxia Ma +7 more
doaj +1 more source
Anti-apoptotic action of zearalenone in MCF-7 cells
Ecotoxicology and Environmental Safety, 2005 Zearalenone (ZEA), a nonsteroidal estrogenic mycotoxin, is present in high concentrations in dairy products and cereals. Studies have indicated that ZEA could strongly provoke proliferation in estrogen-dependent breast cancer MCF-7 cells following estrogen ablation.
Zengli, Yu +3 more
openaire +2 more sources
Advanced Science, EarlyView.This study reveals a hidden chemical weapon among calcareous‐shelled sessile organisms in the intertidal zone: the barnacle Balanus albicostatus releases a synergistic blend of palmitic acid and 1‐palmitoyl‐sn‐glycero‐3‐phosphocholine as the allelochemical with the inhibitory activity against attachment of the mussel Vignadula atrata, which may mediate
Zhuo Li +9 more
wiley +1 more source
Brazilian Journal of Medical and Biological Research, 2012 A dendritic cell (DC)-based vaccine strategy could reduce the risk of recurrence and improve the survival of breast cancer patients. However, while therapy-induced apoptosis of hepatocellular and colorectal carcinoma cells can enhance maturation and ...
Jin Zheng +10 more
doaj +2 more sources
Thermosensitive Hydrogels Loaded with Resveratrol Nanoemulsion: Formulation Optimization by Central Composite Design and Evaluation in MCF-7 Human Breast Cancer Cell Lines [PDF]
, 2022 Sabna Kotta +5 more
openalex +1 more source
An estrogen-dependent esterase activity in MCF-7 cells
Journal of Steroid Biochemistry, 1987 The presence of steroidal esters in hormonally sensitive tissues lends importance to the esterases which convert the biologically inactive adducts to the parent potent forms. Accordingly, esterase-activities were studied in a human breast cancer model--the MCF-7 cell line. Tritiated estradiol esters- estradiol-17-acetate (EA), estradiol-17-valerate (EV)
J, Katz +3 more
openaire +2 more sources
Advanced Science, EarlyView.By integrating a convergent molecular platform strategy, this study designed a novel dual‐target C5 to combat multidrug‐resistant Gram‐negative bacteria. C5 synergistically enhances antibiotic efficacy by inhibiting efflux pumps and increasing bacterial membrane permeability.
Jiale Dong +11 more
wiley +1 more source