Results 1 to 10 of about 24,516,455 (329)

Role of MCP-1 as an inflammatory biomarker in nephropathy. [PDF]

open access: yesFront Immunol, 2023
The Monocyte chemoattractant protein-1 (MCP-1), also referred to as chemokine ligand 2 (CCL2), belongs to the extensive chemokine family and serves as a crucial mediator of innate immunity and tissue inflammation.
Liu Y   +8 more
europepmc   +2 more sources

MCP-1: Function, regulation, and involvement in disease

open access: yesInternational Immunopharmacology, 2021
MCP-1 (Monocyte chemoattractant protein-1), also known as Chemokine (CC-motif) ligand 2 (CCL2), is from family of CC chemokines. It has a vital role in the process of inflammation, where it attracts or enhances the expression of other inflammatory factors/cells.
Sanjiv Singh   +2 more
semanticscholar   +3 more sources

Monocyte Chemoattractant Protein-1 (MCP-1): An Overview

open access: yesJournal of Interferon & Cytokine Research, 2009
Chemokines constitute a family of chemoattractant cytokines and are subdivided into four families on the basis of the number and spacing of the conserved cysteine residues in the N-terminus of the protein. Chemokines play a major role in selectively recruiting monocytes, neutrophils, and lymphocytes, as well as in inducing chemotaxis through the ...
S. Deshmane   +3 more
semanticscholar   +4 more sources

Blood monocyte chemotactic protein-1 (MCP-1) and adapted disease activity Score28-MCP-1: favorable indicators for rheumatoid arthritis activity. [PDF]

open access: yesPLoS ONE, 2013
OBJECTIVE: We assessed blood pentraxin 3 (PTX3) and macrophage chemotactic factor-1 (MCP-1) levels as indicators of disease activity in rheumatoid arthritis (RA) patients, because data on disease activity score 28 (DAS28)-erythrocyte sedimentation rate ...
Lieh-bang Liou   +4 more
doaj   +2 more sources

An Alternative Perspective to the FMF Clinic: MCP-1 (A-2518G) and CCR2 (G190A) Polymorphisms and MCP1 Expression

open access: yesJournal of Contemporary Medicine, 2022
Background: Familial Mediterranean Fever (FMF) is an autoinflammatory disease and may express as various clinical findings. Chemokines are crucial elements of the inflammatory process.
Nadir Koçak, Şenol Çitli
doaj   +3 more sources

MCP-1 binds to oxidized LDL and is carried by lipoprotein(a) in human plasma

open access: yesJournal of Lipid Research, 2013
Lipoprotein oxidation plays an important role in pathogenesis of atherosclerosis. Oxidized low density lipoprotein (OxLDL) induces profound inflammatory responses in vascular cells, such as production of monocyte chemoattractant protein-1 (MCP-1 ...
Philipp Wiesner   +14 more
doaj   +2 more sources

The Chemokine MIG is Associated with an Increased Risk of COVID-19 Mortality in Mexican Patients [PDF]

open access: yesIranian Journal of Immunology, 2022
Background: Coronavirus disease 2019 (COVID-19) is an emergent viral disease in which the host inflammatory response modulates the clinical outcome. Severe outcomes are associated with an exacerbation of inflammation in which chemokines play an important
Luis Ochoa-Ramirez   +10 more
doaj   +1 more source

Network and epigenetic characterization of subsets of genes specifically expressed in maize bundle sheath cells

open access: yesComputational and Structural Biotechnology Journal, 2022
Bundle sheath (BS) cells exhibit dramatically structural differences and functional variations at physiological, biochemical and epigenetic levels as compared to mesophyll (M) cells in maize.
Shentong Tao, Wenli Zhang
doaj   +1 more source

Bindarit Reduces Bone Loss in Ovariectomized Mice by Inhibiting CCL2 and CCL7 Expression via the NF‐κB Signaling Pathway

open access: yesOrthopaedic Surgery, 2022
Objective To investigate the changes in proinflammatory cytokines and chemokines, namely, C‐C motif ligand (CCL) 2 and CCL7, in postmenopausal osteoporosis (PMOP) and to develop a new drug, bindarit (Bnd), for PMOP in an ovariectomized (OVX) mouse model.
Shi‐guo Yuan   +6 more
doaj   +1 more source

IP-10 and MCP-1 as biomarkers associated with disease severity of COVID-19

open access: yesMolecular Medicine, 2020
Background COVID-19 is a viral respiratory disease caused by the severe acute respiratory syndrome-Coronavirus type 2 (SARS-CoV-2). Patients with this disease may be more prone to venous or arterial thrombosis because of the activation of many factors ...
Yu Chen   +11 more
semanticscholar   +1 more source

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