Results 1 to 10 of about 296,114 (287)

An Alternative Perspective to the FMF Clinic: MCP-1 (A-2518G) and CCR2 (G190A) Polymorphisms and MCP1 Expression

open access: yesJournal of Contemporary Medicine, 2022
Background: Familial Mediterranean Fever (FMF) is an autoinflammatory disease and may express as various clinical findings. Chemokines are crucial elements of the inflammatory process.
Nadir Koçak, Şenol Çitli
doaj   +3 more sources

The Chemokine MIG is Associated with an Increased Risk of COVID-19 Mortality in Mexican Patients [PDF]

open access: yesIranian Journal of Immunology, 2022
Background: Coronavirus disease 2019 (COVID-19) is an emergent viral disease in which the host inflammatory response modulates the clinical outcome. Severe outcomes are associated with an exacerbation of inflammation in which chemokines play an important
Luis Ochoa-Ramirez   +10 more
doaj   +1 more source

Network and epigenetic characterization of subsets of genes specifically expressed in maize bundle sheath cells

open access: yesComputational and Structural Biotechnology Journal, 2022
Bundle sheath (BS) cells exhibit dramatically structural differences and functional variations at physiological, biochemical and epigenetic levels as compared to mesophyll (M) cells in maize.
Shentong Tao, Wenli Zhang
doaj   +1 more source

Bindarit Reduces Bone Loss in Ovariectomized Mice by Inhibiting CCL2 and CCL7 Expression via the NF‐κB Signaling Pathway

open access: yesOrthopaedic Surgery, 2022
Objective To investigate the changes in proinflammatory cytokines and chemokines, namely, C‐C motif ligand (CCL) 2 and CCL7, in postmenopausal osteoporosis (PMOP) and to develop a new drug, bindarit (Bnd), for PMOP in an ovariectomized (OVX) mouse model.
Shi‐guo Yuan   +6 more
doaj   +1 more source

Rack1 regulates pro-inflammatory cytokines by NF-κB in diabetic nephropathy

open access: yesOpen Medicine, 2022
Diabetic nephropathy (DN) is one of the chronic microvascular diseases of diabetes. Studies revealed that inflammation is involved in the development of DN. However, its mechanisms are not fully clear. Here, we screened DN-related mRNAs by RNA sequencing
Wu Keqian   +8 more
doaj   +1 more source

Experimental hypersensitivity pneumonitis: role of MCP-1 [PDF]

open access: yesJournal of Laboratory and Clinical Medicine, 2003
Inhalation of Saccharopolyspora rectivirgula causes "farmer's lung" disease, a classic example of hypersensitivity pneumonitis (HP). Monocyte chemoattractant protein-1 (MCP-1) is increased in the bronchoalveolar lavage fluid of mice challenged with S rectivirgula, and S rectivirgula induces MCP-1 secretion by alveolar macrophages.
Schuyler, Mark   +2 more
openaire   +2 more sources

Monomeric Monocyte Chemoattractant Protein-1 (MCP-1) Binds and Activates the MCP-1 Receptor CCR2B [PDF]

open access: yesJournal of Biological Chemistry, 1998
To address the role of dimerization in the function of the monocyte chemoattractant protein-1, MCP-1, we mutated residues that comprise the core of the dimerization interface and characterized the ability of these mutants to dimerize and to bind and activate the MCP-1 receptor, CCR2b. One mutant, P8A*, does not dimerize.
C D, Paavola   +12 more
openaire   +2 more sources

The miR-145 rs353291 C allele increases susceptibility to atherosclerosis

open access: yesFrontiers in Bioscience-Landmark, 2020
Atherosclerosis (AS) is one of the leading causes of death, with variable frequencies in different populations. To this end, we examined whether AS is associated with the miR-145 rs353291 polymorphism and specific rs353291 alleles.
Yu Lv   +5 more
doaj   +1 more source

Data on early postoperative changes in aqueous monocyte chemoattractant protein-1 levels after phacoemulsification

open access: yesData in Brief, 2016
The data presented in this article are related to the research article entitled “Elevated levels of monocyte chemoattractant protein-1 in the aqueous humor after phacoemulsification” (M. Kawai, T. Inoue, M. Inatani, N. Tsuboi, K. Shobayashi, A. Matsukawa,
Motofumi Kawai   +3 more
doaj   +1 more source

trans-Chalcone protects male rats against high-fat emulsion-induced pancreatic injury by inhibiting TNF-α and MCP-1 expression [PDF]

open access: yesمجله پزشکی دانشگاه علوم پزشکی تبریز, 2023
Background. High-fat diet (HFD) intake is linked to ectopic fat deposition in the pancreas. It also causes pancreatic inflammatory lesions. trans-Chalcone is a simple chalcone with protective effects against HFD-induced metabolic disorders.
Elham Karimi-Sales   +1 more
doaj   +1 more source

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