Results 161 to 170 of about 3,352 (198)

Carcinoma de células de Merckel humano e sua potencial associação com o recémdescrito poliomavírus MCPyV: avaliação preliminar de biopsias e análise de casualidade

, 2008
Danielle Amorim
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MCPyV-ΔNLS VP1 fails to form pseudovirions.

Karen Wang (288073), Adrienne N. Eady (21453612), Isabel Amaya (21453615), Alina Stanczak (21453618), Chelsey C. Spriggs (13730845)   +4 more
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Spatially organized inflammatory myeloid-CD8⁺T cell aggregates linked to Merkel-cell Polyomavirus driven Reorganization of the Tumor Microenvironment

Haist M, Matusiak M, Tan Y, Zimmer S, Stege H, Kempchen TN, Mitschke S, Chu P, Weidenthaler-Barth B, Barlow GL, Rogall F, Delgado Gonzalez A, Baertsch M, Albertini S, Gariglio M, Borgogna C, Goltsev Y, Grabbe S, Hickey JW, Nolan GP.   +19 more
europepmc   +1 more source

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MCPyV-Negative Merkel Cell Carcinoma In Situ Associated With Immunosuppression.

The American Journal of Dermatopathology, 2023
Merkel cell carcinoma (MCC) is a rare and aggressive cutaneous neoplasm that is almost always intradermal. Immunosuppression increases the risk of MCC, which is believed to be due to increased susceptibility to Merkel cell polyomavirus (MCPyV ...
Anika Mazumder, Pooria Khoshnoodi, Jessica Gruber, N. Burkemper   +3 more
semanticscholar   +3 more sources

Merkel cell polyomavirus (MCPyV) DNA prevalence in brazilian blood donors.

Transfusion Clinique et Biologique, 2022
Merkel cell polyomavirus (MCPyV) is an oncogenic virus that has been etiologically linked to Merkel cell carcinoma. Low levels of MCPyV DNA have been detected in blood donors with unclear impact on transfusion.
V. S. Zucherato, P. N. D. da Costa, M. Giovanetti, L. F. Krause, Daiani Cristina Cilião Alves, Renata Maria Alencar Moreira, B. M. S. Pimentel, R. Haddad, H. T. Bitencourt, M. Ciccozzi, L. Alcântara, S. Kashima, D. Covas, S. Slavov   +13 more
semanticscholar   +3 more sources

Molecular evidence for selinexor as a treatment for Merkel cell polyomavirus (MCPyV)‐positive Merkel cell carcinoma

International Journal of Dermatology, 2022
promoting protein regulated by MCPyV LTA and in MCCP cells which can be upregulated up to sevenfold. 5 Selinexor’s ability to downregulate critical biomarkers of MCC carcinogenesis shows that it may be a clinically viable modality for MCCP management ...
Brooke R Bartley, R. Simonette, P. Rady, H. Doan, S. Tyring   +4 more
semanticscholar   +3 more sources

Whole genome sequencing elucidates etiological differences in MCPyV-negative Merkel cell carcinoma.

Pathology - Research and Practice
Merkel cell carcinoma (MCC) is an aggressive neuroendocrine neoplasm of the skin. Immunosuppression, ultraviolet radiation and the integration of Merkel cell polyomavirus (MCPyV) have all been shown to be involved in the pathogenesis of this malignancy ...
C. Stephan, Majd Al Assaad, Max F. Levine, Aditya Deshpande, M. Sigouros, J. Manohar, A. Sboner, O. Elemento, A. Pavlick, Juan Miguel Mosquera   +9 more
semanticscholar   +3 more sources

A short intrinsically disordered domain of MCPyV ALTO regulates host TBK1 signaling and MCPyV latency

bioRxiv
Abstract Merkel Cell Polyomavirus (MCPyV) is an oncogenic human polyomavirus that latently infects most adults. Although the causative link between MCPyV and Merkel Cell Carcinoma (MCC) is well established, the molecular mechanisms that govern viral latency and prevent oncogenic progression remain poorly understood.
Taylor E. Senay, Xiaomei Li, Sneha G. Shirhattikar, Tiana T. Luo, Jianxin You   +4 more
semanticscholar   +3 more sources

Merkel Cell Polyomavirus (MCPyV)

, 2020
No abstract available.
Asioli Sofia, C. Ricci
semanticscholar   +3 more sources

Merkel cell polyomavirus (MCPyV) strains in Japanese merkel cell carcinomas (MCC) are distinct from Caucasian type MCPyVs: genetic variability and phylogeny of MCPyV genomes obtained from Japanese MCPyV-infected MCCs

Virus Genes, 2013
Most of merkel cell carcinomas (MCC), a rare, aggressive skin cancer with neuroendocrine features, harbor merkel cell polyomavirus (MCPyV). Seroepidemiological studies suggested high prevalence of MCPyV in the human population. More than ten sequence data on MCPyV strains in Japan have been available, whereas most sequence data were detected from ...
Michiko, Matsushita, Takeshi, Iwasaki, Satoshi, Kuwamoto, Masako, Kato, Keiko, Nagata, Ichiro, Murakami, Yukisato, Kitamura, Kazuhiko, Hayashi   +7 more
openaire   +2 more sources