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Carcinome de Merkel : valeur pronostique et intérêt clinique de la sérologie contre MCPyV

Annales de Dermatologie et de Vénéréologie, 2014
Introduction Le carcinome neuroendocrine primitif cutane ou carcinome de Merkel (CM), est un cancer cutane rare mais agressif, avec une mortalite de 46 %. Il n’existe pas de marqueurs biologiques pour le suivi des patients. 80 % des CM presentent l’integration clonale du polyomavirus des cellules de Merkel (MCPyV) et l’expression de l’oncoproteine ...
A. Blom   +12 more
openaire   +1 more source

Replikace polyomaviru Merkelových buněk (MCPyV) v lidských buněčných kulturách

2022
The Merkel cell polyomavirus (MCPyV) is the only human polyomavirus classified as probably carcinogenic to humans and is the causal factor of a rare aggressive skin malignancy the Merkel cell carcinoma (MCC) in around 80% of cases. Nevertheless, in addition to skin the virus was detected in various body tissues. In spite of that an ideal in vitro model
openaire   +1 more source

Charakterizace imunitní odpovědi proti lidskému polyomaviru MCPyV.

2013
Characterization of immune responses to human polyomavirus MCPyV There have been considerable increase in number of known human polyomaviruses in recent years; currently we register twelve of them. Presumably, majority of human polyomaviruses cause lifelong persistent infection. Primary infection is usually asymptomatic and is followed by appearance of
openaire   +1 more source

Prognostic Impact of MCPyV and TIL Subtyping in Merkel Cell Carcinoma: Evidence from a Large European Cohort of 95 Patients

Endocrine pathology, 2019
C. Ricci   +12 more
semanticscholar   +1 more source

Genetic profiles of different subsets of Merkel cell carcinoma show links between combined and pure MCPyV-negative tumors.

Human Pathology, 2018
Michael D Carter   +6 more
semanticscholar   +1 more source

Sérotypes du MCPyV

2015
Touzé, Antoine   +2 more
openaire   +1 more source

Role T antigenů polyomaviru Merkelových buněk (MCPyV) v kancerogenezi

Merkel cell polyomavirus (MCPyV) is a virus with double-stranded DNA genome that mostly causes an asymptomatic primary infection, followed by the establishment of viral persistence, making this virus a part of normal skin microbiota. Under certain circumstances, mutations of the viral genome may occur, which are associated with its integration into the
openaire   +1 more source

Detection of human polyomaviruses MCPyV, HPyV6, and HPyV7 in malignant and non‐malignant tonsillar tissues

Journal of Medical Virology, 2016
M. Saláková   +4 more
semanticscholar   +1 more source

Natural killer cell response is a predictor of good outcome in MCPyV+ Merkel cell carcinoma: A case series of 23 patients

Journal of American Academy of Dermatology, 2017
V. Laniosz   +5 more
semanticscholar   +1 more source

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