Results 71 to 80 of about 24,617,760 (271)

Advances in 3D Bioprinting for Breast Cancer Modeling: Tumor Microenvironment, Metastasis, and Drug Screening

Advanced Healthcare Materials, EarlyView.
Three‐dimensional bioprinting transforms breast cancer modeling from simple constructs into spatially organized, multicellular, perfused, and patient‐derived platforms. This review shows how bioinks, cellular composition, architecture, and flow govern tumor behavior and drug response, while revealing why complexity alone is insufficient without ...
Mustafa Nakipoglu, Mahboobeh Mahmoodi, Ehsanul Hoque Apu, Fahimeh Shahabipour, Sibel Emir Diltemiz, Sanjib Saha, Halima Alem, Nureddin Ashammakhi   +7 more
wiley   +1 more source

Emergence of a novel mobile colistin resistance gene, mcr-8, in NDM-producing Klebsiella pneumoniae

Emerging Microbes and Infections, 2018
The rapid increase in carbapenem resistance among gram-negative bacteria has renewed focus on the importance of polymyxin antibiotics (colistin or polymyxin E). However, the recent emergence of plasmid-mediated colistin resistance determinants (mcr-1, -2,
Xiaoming Wang, Yao Wang, Ying Zhou, Jiyun Li, Wenjuan Yin, Shaolin Wang, Suxia Zhang, Jianzhong Shen, Zhangqi Shen, Yang Wang   +9 more
doaj   +1 more source

Resistance to Overdoping Allows Over 2000 S cm−1 Conductivity in P(g3BTTT) With Anion‐Exchange Doping

Advanced Materials, EarlyView.
Anion‐exchange doping of conjugated polymers is an effective way to achieve high conductivities. Here, we report over 2000 S cm−1 electrical conductivity for doped P(g3BTTT). In addition, we show that P(g3BTTT) sustains exceptionally high doping levels without any drop in the charge mobility.
Basil Hunger, Maximilian M. Horn, Eva Röck, Diego Rosas Villalva, Lize Bynens, Jochen Vanderspikken, Christina Kousseff, Silène Gobeil, Olivier Bardagot, Nesibe Akmanşen‐Kalayci, Sarah H. Tolbert, Iain McCulloch, Wouter Maes, Demetra Tsokkou, Natalie Banerji   +14 more
wiley   +1 more source

Screening for fecal carriage of MCR-producing Enterobacteriaceae in healthy humans and primary care patients

Antimicrobial Resistance and Infection Control, 2017
Background The extent of the occurrence of the plasmid-encoded colistin resistance genes mcr-1 and mcr-2 among humans is currently sparsely studied in Western Europe.
Katrin Zurfluh, Roger Stephan, Andreas Widmer, Laurent Poirel, Patrice Nordmann, Hans-Jakob Nüesch, Herbert Hächler, Magdalena Nüesch-Inderbinen   +7 more
doaj   +1 more source

A dilemma resolved? Towards a revised philosophy of conservation education [PDF]

, 2002
The guidelines for conservation education agreed by the European Confederation of Conservator-restorers’ Organisations’ state that “The only reasonable way of training in conservation/restoration is full time at university level or at an equivalent level,
Schiro, Joseph, Conference on Scientific Aspects of Conservation, Cannataci, Joseph A., Caruana, Martina, Malta Centre for Restoration (MCR)   +4 more
core  

Nuclear Pore Mechanotransduction in Oncology: A Structural Axis of Vulnerability for Targeted Intervention

Advanced Materials, EarlyView.
Cancer‐associated NPC remodeling creates a high‐flux, low‐stringency nuclear state that supports malignant adaptation but increases mechanical fragility. Targeting the FG‐barrier or NPC scaffold may drive mechanostat failure, envelope rupture, DNA damage, and loss of nuclear integrity.
Sílvio Terra Stefanello, Caren Rigon Mizdal, Aline Franzen da Silva, Yun Qian, Wei‐En Yuan, Victor Shahin   +5 more
wiley   +1 more source

Spread of MCR-3 Colistin Resistance in China: An Epidemiological, Genomic and Mechanistic StudyResearch in Context

EBioMedicine, 2018
Background: Mobilized resistance to colistin is evolving rapidly and its global dissemination poses a severe threat to human health and safety. Transferable colistin resistance gene, mcr-3, first identified in Shandong, China, has already been found in ...
Yongchang Xu, Lan-Lan Zhong, Swaminath Srinivas, Jian Sun, Man Huang, David L. Paterson, Sheng Lei, Jingxia Lin, Xin Li, Zichen Tang, Siyuan Feng, Cong Shen, Guo-Bao Tian, Youjun Feng   +13 more
doaj   +1 more source

All‐Amyloid Functional Coacervates

Advanced Materials, EarlyView.
This study introduces an all‐amyloid interfacial complex coacervate technique that employs charge‐mediated or functionalization‐assisted complexation of oppositely charged food protein‐derived amyloid nanofibrils to engineer functional soft constructs across multiple length scales.
Seyyed Alireza Hashemi, Mohammad Peydayesh, Laura Baraldi, Mohammad Arjmand, Raffaele Mezzenga   +4 more
wiley   +1 more source

A Multifunctional Ionograsper Enabling Ion‐Redistribution Proximity Sensing and Structural‐Reconfiguration‐Driven Bidirectional Actuation

Advanced Materials, EarlyView.
A solid‐state ionic actuator integrates sensing, actuation, and memory within one material. A brief UV pulse induces long‐lasting deformation via coupled network rearrangement, dehydration, and rehydration, while ionic redistribution enables self‐powered sensing, supporting multifunctional, energy‐efficient soft robotic functions without continuous ...
Yong Min Kim, Jin Han Kwon, Hyeon Woo Yang, Sungryong Kim, Gyeong Rok Lee, Hong Chul Moon   +5 more
wiley   +1 more source

Plasmid-mediated colistin resistance and ESBL production in Escherichia coli from clinically healthy and sick pigs

Scientific Reports, 2022
This study aimed to determine the percentage of colistin resistant and ESBL-producing Escherichia coli from clinically sick and healthy pigs and understand the molecular mechanisms underlying colistin resistance and ESBL production.
Suthathip Trongjit, Pornchalit Assavacheep, Sukuma Samngamnim, Tran Hoang My, Vo Thi Tra An, Shabbir Simjee, Rungtip Chuanchuen   +6 more
doaj   +1 more source