Results 71 to 80 of about 29,557 (243)

An Evolutionarily Conserved Mechanism for Intrinsic and Transferable Polymyxin Resistance

mBio, 2018
Polymyxins, a family of cationic antimicrobial cyclic peptides, act as a last line of defense against severe infections by Gram-negative pathogens with carbapenem resistance.
Yongchang Xu, Wenhui Wei, Sheng Lei, Jingxia Lin, Swaminath Srinivas, Youjun Feng   +5 more
doaj   +1 more source

Boolean Logic‐Based Control Over Recombinant Protein Biomaterial Degradability and Therapeutic Delivery

Advanced Materials, EarlyView.
Fully recombinant protein‐based biomaterials execute complex Boolean logic for user‐programmable material degradation and concomitant therapeutic cargo release. Biologics, such as growth factors, can be incorporated within the crosslinkers as “drugamers”, while encapsulated cells can be released according to nested YES/OR/AND‐type logical operations ...
Murial L. Ross, Ryan Gharios, Shivani Kottantharayil, Cole A. DeForest   +3 more
wiley   +1 more source

Alkaline Peptone Water-Based Enrichment Method for mcr-3 From Acute Diarrheic Outpatient Gut Samples

Frontiers in Medicine, 2018
A third plasmid-mediated colistin resistance gene, mcr-3, is increasingly being reported in Enterobacteriaceae and Aeromonas spp. from animals and humans. To investigate the molecular epidemiology of mcr in the gut flora of Chinese outpatients, 152 stool
Qiaoling Sun, Yanyan Hu, Hongwei Zhou, Lingbin Shu, Hanyu Wang, Zixian Huang, Rong Zhang   +6 more
doaj   +1 more source

Hybrid Amyloid–Boron Nitride Aerogels for Lightweight Sound Insulation

Advanced Materials, EarlyView.
Amyloid fibrils template the mild formation of boron nitride–rich hybrid aerogels with hierarchical porosity, enhanced BN‐like ordering, and fibril‐reinforced mechanics. These ultralight materials combine thermal stability with strong sound absorption and transmission loss, offering a sustainable bio‐assisted route toward lightweight acoustic shields ...
Mohammad Peydayesh, Andrin Lustgarten, Stefan Schoenwald, Enrico Boschi, My Hanh Bui, Ali Miserez, Felix Donat, Christoph R. Müller, Raffaele Mezzenga   +8 more
wiley   +1 more source

Emergence of plasmid-mediated mcr genes from Gram-negative bacteria at the human-animal interface

Gut Pathogens, 2020
Background The global emergence of plasmid-mediated colistin resistance (Col-R) conferred by mcr genes in gram-negative rods (GNRs) has jeopardized the last treatment option for multidrug-resistant bacterial infections in humans.
Humera Javed, Sidrah Saleem, Aizza Zafar, Aamir Ghafoor, Ahmad Bin Shahzad, Hasan Ejaz, Kashaf Junaid, Shah Jahan   +7 more
doaj   +1 more source

High‐Performance Bio‐Glue From the Berries of a Parasitic Plant

Advanced Materials, EarlyView.
We report a fully bio‐based adhesive derived primarily from a (poly)saccharide extract obtained from the berries of the hemi‐parasitic plant mistletoe (Viscum album), supplemented with tannic and malic acid without any further chemical functionalization.
Ufuk Gürer, Jana T. Reh, Jonas Röder, Umut Günsel, Chiara Gunnella, Lisa Schöbel, Franz Hagn, Aldo R. Boccaccini, Oliver Lieleg   +8 more
wiley   +1 more source

E-p-Methoxycinnamoyl-α-l-rhamnopyranosyl Ester, a Phenylpropanoid Isolated from Scrophularia buergeriana, Increases Nuclear Factor Erythroid-Derived 2-Related Factor 2 Stability by Inhibiting Ubiquitination in Human Keratinocytes

Molecules, 2018
The nuclear factor erythroid-derived 2-related factor 2 (Nrf2) is a key regulator of gene expression during oxidative stress and drug detoxification. Thus, identifying Nrf2 activators to protect from possible cell damage is necessary.
Jiwon Jeong, Lilik Duwi Wahyudi, Young-Sam Keum, Heejung Yang, Jung-Hwan Kim   +4 more
doaj   +1 more source

1‐D Collocated Dual‐Gradient Sensory Fibers for Comprehensive Sensing and Decoding of Complex Human Motion and Physiology

Advanced Materials, EarlyView.
Coupled materials design enables a monolithic fiber that integrates complementary sensing regimes into a single wearable strand. By preserving informative signal features across subtle physiological deformation, large body motion, and mixed mechanical inputs, the dual‐gradient architecture generates synchronized, less redundant outputs that improve ...
Yunheum Lee, Sungha Jeon, Min Kim, Joonhee Won, Jinwook Yeo, Kyunghyun Jo, Soyeon Lee, Kieun Park, Yechan Yang, Chul Kim, Gun‐Hee Lee, Seunghwa Ryu, Sungho Jo, Seongjun Park   +13 more
wiley   +1 more source

Additively Manufactured Porous Ceramics as Tunable Dielectrics for Passive Temperature Sensing

Advanced Materials Technologies, EarlyView.
Porous ceramic lattices, 3D‐printed from a multicomponent oxide ink, are integrated with LC resonators for passive wireless temperature sensing. By tuning porosity, the dielectric properties and RF response are engineered to produce distinct resonant frequency shifts with temperature. The results establish a structure‐driven approach to customizing the
Sogol Heidarishahrivar, Aminul Islam, Chang Woo Gal, Insup Kim, Yeong‐Jin Choi, Woo Soo Kim   +5 more
wiley   +1 more source

Spheroid‐On‐A‐Drop: A Modular Droplet Microfluidics Platform

Advanced Materials Technologies, EarlyView.
The proposed Spheroid‐on‐a‐Drop platform represents a reproducible and tunable platform for the fabrication of biocompatible GelMA‐based microgels, able to support controlled 3D tumor spheroid culture. Its precise control over droplet dynamics and cell distribution paves the way for advanced applications in tissue modeling, drug screening, and ...
A. Fergola, V. Vighetto, G. Mesiano, A. Cosola, S. L. Marasso, M. Cocuzza, C. F. Pirri, L. Napione, F. Frascella   +8 more
wiley   +1 more source