Results 151 to 160 of about 2,036 (174)

Competition between distinct ApoE alleles and mCRP for the endothelial receptor CD31 differentially regulates neurovascular inflammation and Alzheimer’s disease pathology [PDF]

bioRxiv, 2021
BACKGROUND C-reactive protein (CRP) in peripheral inflammation is associated with increased Alzheimer’s disease (AD) risk in Apolipoprotein E4 (ApoE4), but not ApoE3 or E2, humans.
Zhengrong Zhang, Hana Na, Qini Gan, Q. Tao, Y. Alekseyev, Junming Hu, Zili Yan, Jack B. Yang, Hua Tian, Shenyu Zhu, Qiang Li, Ibraheem Rajab, J. K. Blusztajn, B. Wolozin, A. Emili, Xiaoling Zhang, T. Stein, L. Potempa, W. Qiu   +18 more
semanticscholar   +2 more sources

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Circulating levels of the pro-inflammatory monomeric isoform of C-reactive protein (mCRP) correlate with inflammatory markers in patients with stage II-III colon cancer.

Journal of Clinical Oncology, 2023
e15641 Background: Tumor-promoting inflammation is an established hallmark of cancer. C-reactive protein (CRP) is one of the most studied negative prognostic markers of the systemic inflammatory response (SIR) and known to be implicated in detrimental ...
A. J. Fuglestad, P. Bousquet, A. H. Kostner, S. Meltzer, A. H. Ree, R. Fernandez-Botran, C. Kersten   +6 more
semanticscholar   +2 more sources

Evaluating Beneficiary Perceptions of the Impact of WASH Infrastructure Under the Multi-Sectoral Crisis Recovery Project (MCRP) in Adamawa State, North-East Nigeria

International Research Journal of Innovations in Engineering and Technology
This study assesses the impact of Water, Sanitation, and Hygiene (WASH) infrastructure projects implemented under the Multi-Sectoral Crisis Recovery Project (MCRP) in Adamawa State, North-East Nigeria.
Maurice Vunobolki, E. Joel, Sadiq Bariki, S. Shuaib, Hassan Misari, D. Tizhe   +5 more
semanticscholar   +2 more sources

MCRP Post-Distribution Evaluation of Solar Pumps: Enhancing Agricultural Productivity While Reducing Carbon Footprints Case Study of Adamawa State

International Journal of Research and Innovation in Social Science
This study presents a comprehensive post-distribution evaluation of solar-powered irrigation pumps distributed under the MCRP project in Adamawa State, Nigeria.
Maurice Vunobolki, Julius Mbidomti, E. Joel, Hassan Misari, Ibrahim Bayaso, Thabbal, Mikah Lakumna   +5 more
semanticscholar   +2 more sources

mCRP as a Biomarker of ANCA‐Associated Vasculitis

International Journal of Rheumatic Diseases
Chitose K. Fujita, Yasuo Sakurai, Yuki Yasuda, Masaaki Fujita   +3 more
semanticscholar   +3 more sources

Abdominal lymphatic system visibility, morphology, and abnormalities in children as seen on routine MCRP and its association with immune-mediated diseases

European Radiology, 2020
(1) To assess the visibility and diameters of the thoracic duct (TD) and cisterna chyli (CC) on MR cholangiopancreatography (MRCP) in children. (2) To evaluate for the presence of any lymphatic abnormalities and assess their association with diseases in which the immune system is implicated in etiopathogenesis.This retrospective study included 142 ...
Ebtehaj Alshehri, Christopher Z. Lam, B. Kamath, G. Chavhan   +3 more
semanticscholar   +3 more sources

Targeted silencing of mCRP (CD46, CD55, CD59) by siRNA encapsulated in transferrin-liposomes specifically sensitizes cancer cells to complement attack

Immunobiology, 2012
Srinivas Mamidi, M. Kirschfink
semanticscholar   +2 more sources

Obstacles to cancer immunotherapy: expression of membrane complement regulatory proteins (mCRPs) in tumors

Molecular Immunology, 2003
Monoclonal antibodies (mAbs) are being increasingly used in cancer therapy owing to their ability to recognize specifically cancer cells and to activate complement- and cell-mediated cytotoxicity and/or to induce growth arrest or apoptosis. The therapeutic potential of anticancer antibodies is significantly limited due to the ability of cancer cells to
Z, Fishelson, N, Donin, S, Zell, S, Schultz, M, Kirschfink   +4 more
openaire   +2 more sources

Dynamics of circulating monomeric C-reactive protein (mCRP) to predict outcomes with first-line alternating oxaliplatin-based chemotherapy and nivolumab in metastatic microsatellite-stable (MSS) colorectal cancer (CRC).

Journal of Clinical Oncology
3606 Background: Elevated CRP levels at CRC diagnosis are consistently associated with poor outcomes, suggesting a tumor-promoting and potentially immuno-suppressive inflammatory state. The clinically assessed CRP is a pentameric protein that can
A. J. Fuglestad, P.A. Bousquet, L. Potempa, Marc Potempa, S. Meltzer, C. Kersten, A. H. Ree   +6 more
semanticscholar   +1 more source