Results 161 to 170 of about 2,036 (174)

Cell membranes and liposomes dissociate C‐reactive protein (CRP) to form a new, biologically active structural intermediate: mCRP _m

The FASEB Journal, 2006
Emerging evidence indicates that C‐reactive protein (CRP) has at least two conformationally distinct isoforms, i.e ., pentameric CRP (pCRP) and monomeric CRP (mCRP or CRP subunit). Both CRP isoforms are proposed to play roles in inflammation and may participate in the pathogenesis of ...
Shang-Rong, Ji, Yi, Wu, Li, Zhu, Lawrence A, Potempa, Fen-Ling, Sheng, Wei, Lu, Jing, Zhao   +6 more
openaire   +2 more sources

Stimulation of megakaryocytopoiesis in mice by human modified C-reactive protein (mCRP)

Experimental hematology, 1996
The prototypic human acute phase reactant, C-reactive protein (CRP), and a structurally modified form of CRP (mCRP) were studied as agents which could stimulate thrombopoiesis in both in vitro and in vivo mouse models. mCRP, but not the widely studied (native) pentameric form of CRP, demonstrated significant megakaryocyte colony-stimulating activity ...
L A, Potempa, M, Motie, K E, Wright, B L, Crump, J A, Radosevich, N, Sakai, G, Lai, K, Tanaka, E, Kojima, A, Tsuboi, L G, Hua   +10 more
openaire   +1 more source

Neeko: Leveraging Dynamic LoRA for Efficient Multi-Character Role-Playing Agent

Conference on Empirical Methods in Natural Language Processing
Large Language Models (LLMs) have revolutionized open-domain dialogue agents but encounter challenges in multi-character role-playing (MCRP) scenarios.
Xiaoyan Yu, Tongxu Luo, Yifan Wei, Fangyu Lei, Yiming Huang, Penghui Hao, Liehuang Zhu   +6 more
semanticscholar   +1 more source

Paediatric option in MRCP examination: a survey into the results of candidates electing to take the paediatrics option in MRCP (UK) Part II

Medical Education, 1977
Summary Five surveys on the performance of candidates in the paediatric option at MRCP(UK) Part II examination show the paediatric candidates to be at a disadvantage in the written part. The paediatric candidate is later in his career to obtain his MRCP (UK), as the mean interval from qualification to success at ...
openaire   +2 more sources

Monomeric C-Reactive Protein in Atherosclerotic Cardiovascular Disease: Advances and Perspectives

International Journal of Molecular Sciences, 2023
Ivan Melnikov, Sergey Kozlov, Yuliya Avtaeva   +2 more
exaly  

Targeted downregulation of mCRPs (CD46, CD55, and CD59) specifically sensitizes transferrin-receptor (CD71) high expressing malignant cells to complement attack

Molecular Immunology, 2011
M.C. Cinci, S. Mamidi, M. Kirschfink
openaire   +1 more source

AMD associated Y402H polymorphism affects binding of the complement regulator mCRP and results in an altered complement control on necrotic ARPE-19 cells

Molecular Immunology, 2009
Nadine Lauer, Michael Mihlan, Bernhard H.F. Weber, Frank Sühnel, Claudia v. Strachwitz, Andrea Hartmann, Peter F. Zipfel, Christine Skerka   +7 more
openaire   +1 more source

Advantages of mCRP over pCRP in diagnosis of autoimmune diseases

, 2014
A. Myint, R. Berghmans
semanticscholar   +1 more source

Multimeric FHR4 immunoconjugates promote efficient activation of CAP on Her2 tumour cells, further controlled by overexpressed mCRPs, limiting MAC formation and CDC

Molecular Immunology, 2017
Jean-Marc Plesseria, Charlène Verschueren, Gilles Iserentant, Jacques H.M. Cohen, Carole Devaux, Xavier Dervillez   +5 more
openaire   +1 more source

Cell membranes and liposomes dissociate C‐reactive protein (CRP) to form a new, biologically active structural intermediate: mCRP m

FASEB Journal, 2007
Shang-Rong Ji, Li Zhu, Lawrence A Potempa   +2 more
exaly