Results 161 to 170 of about 3,242 (179)

Exploring the role of inflammation in age-related macular degeneration: new insights and implications for future therapies. [PDF]

Rom J Morphol Embryol
Borodi PG, Slevin M.
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Role of MCRP in the clinical management and the pathophysiology of the acute coronary syndromes

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Obstacles to cancer immunotherapy: expression of membrane complement regulatory proteins (mCRPs) in tumors

Molecular Immunology, 2003
Monoclonal antibodies (mAbs) are being increasingly used in cancer therapy owing to their ability to recognize specifically cancer cells and to activate complement- and cell-mediated cytotoxicity and/or to induce growth arrest or apoptosis. The therapeutic potential of anticancer antibodies is significantly limited due to the ability of cancer cells to
Z, Fishelson, N, Donin, S, Zell, S, Schultz, M, Kirschfink   +4 more
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Circulating levels of the pro-inflammatory monomeric isoform of C-reactive protein (mCRP) correlate with inflammatory markers in patients with stage II-III colon cancer.

Journal of Clinical Oncology, 2023
e15641 Background: Tumor-promoting inflammation is an established hallmark of cancer. C-reactive protein (CRP) is one of the most studied negative prognostic markers of the systemic inflammatory response (SIR) and known to be implicated in detrimental immune responses. Circulating CRP, as measured in routine practice, is a pentameric structure (pCRP).
Anniken Joerlo Fuglestad, Paula Anna Bousquet, Anne Helene Køstner, Sebastian Meltzer, Anne Hansen Ree, Rafael Fernandez-Botran, Christian Kersten   +6 more
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Abdominal lymphatic system visibility, morphology, and abnormalities in children as seen on routine MCRP and its association with immune-mediated diseases

European Radiology, 2020
(1) To assess the visibility and diameters of the thoracic duct (TD) and cisterna chyli (CC) on MR cholangiopancreatography (MRCP) in children. (2) To evaluate for the presence of any lymphatic abnormalities and assess their association with diseases in which the immune system is implicated in etiopathogenesis.This retrospective study included 142 ...
Ebtehaj AlShehri, Christopher Z. Lam, Binita M. Kamath, Govind B. Chavhan   +3 more
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Cell membranes and liposomes dissociate C‐reactive protein (CRP) to form a new, biologically active structural intermediate: mCRP _m

The FASEB Journal, 2006
Emerging evidence indicates that C‐reactive protein (CRP) has at least two conformationally distinct isoforms, i.e ., pentameric CRP (pCRP) and monomeric CRP (mCRP or CRP subunit). Both CRP isoforms are proposed to play roles in inflammation and may participate in the pathogenesis of ...
Shang-Rong, Ji, Yi, Wu, Li, Zhu, Lawrence A, Potempa, Fen-Ling, Sheng, Wei, Lu, Jing, Zhao   +6 more
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Stimulation of megakaryocytopoiesis in mice by human modified C-reactive protein (mCRP)

Experimental hematology, 1996
The prototypic human acute phase reactant, C-reactive protein (CRP), and a structurally modified form of CRP (mCRP) were studied as agents which could stimulate thrombopoiesis in both in vitro and in vivo mouse models. mCRP, but not the widely studied (native) pentameric form of CRP, demonstrated significant megakaryocyte colony-stimulating activity ...
L A, Potempa, M, Motie, K E, Wright, B L, Crump, J A, Radosevich, N, Sakai, G, Lai, K, Tanaka, E, Kojima, A, Tsuboi, L G, Hua   +10 more
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MCRP Post-Distribution Evaluation of Solar Pumps: Enhancing Agricultural Productivity While Reducing Carbon Footprints Case Study of Adamawa State

International Journal of Research and Innovation in Social Science
This study presents a comprehensive post-distribution evaluation of solar-powered irrigation pumps distributed under the MCRP project in Adamawa State, Nigeria. The research assesses gender participation, age and educational profiles of beneficiaries, adoption timelines, crop patterns, and the impact of solar irrigation on agricultural productivity ...
Maurice Vunobolki, Julius Mbidomti, Eli Joel, Hassan Misari, Ibrahim Bayaso, Thabbal, Mikah Lakumna   +5 more
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