Results 141 to 150 of about 1,780 (172)
pCRP-mCRP Dissociation Mechanisms as Potential Targets for the Development of Small-Molecule Anti-Inflammatory Chemotherapeutics [PDF]
Frontiers in Immunology, 2018 Circulating C-reactive protein (CRP) is a key acute-phase protein and one of the main clinical biomarkers for inflammation and infection. CRP is an important upstream mediator of inflammation and is associated with the onset of a number of important disease states including cardiovascular disease and neurodegenerative disorders such as Alzheimer's ...
Mario di Napoli +2 more
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mCRP triggers angiogenesis by inducing F3 transcription and TF signalling in microvascular endothelial cells [PDF]
Thrombosis and Haemostasis, 2017 SummaryInflammation contributes to vascular disease progression. However, the role of circulating inflammatory molecules on microvascular endothelial cell (mECs) is not fully elucidated. The aim of this study was to investigate the effects of the short pentraxin CRP on microvascular endothelial cell angiogenic function.
Gemma Arderiu +2 more
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mCRP-Induced Focal Adhesion Kinase-Dependent Monocyte Aggregation and M1 Polarization, Which Was Partially Blocked by the C10M Inhibitor [PDF]
International Journal of Molecular SciencesMonomeric C-reactive protein (mCRP) has recently been implicated in the abnormal vascular activation associated with development of atherosclerosis, but it may act more specifically through mechanisms perpetuating damaged vessel inflammation and subsequent aggregation and internalization of resident macrophages.
Doina Manu +2 more
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Monomeric C reactive protein (mCRP) regulates inflammatory responses in human and mouse chondrocytes [PDF]
Laboratory Investigation, 2021 C-reactive protein (CRP) is an acute-phase protein that is used as an established biomarker to follow disease severity and progression in a plethora of inflammatory diseases. However, its pathophysiologic mechanisms of action are still poorly defined and remain elusive. CRP, in its pentameric form, exhibits weak anti-inflammatory activity.
Ali Mobasheri +2 more
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Journal of King Saud University - Computer and Information Sciences, 2022 Sensor nodes consume their energy quickly due to their continuous perception, routing, and internal circuit mechanisms in Wireless Sensor Networks (WSNs). Especially, the nodes that are close to the sink node consume their energy more quickly, causing the hot spot problem.
Ebubekir Erdem, Sercan Yalcin
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MCRP Community Planning Graduate Studio 2005/06: King City Community Plan
Focus the Journal of Planning Practice and Education, 2006 During the current academic year, the City and Regional Planning Department graduate Community Planning Studio is engaged in important community-outreach that will make a difference in King City CA. Nuworsoo and Topping, the class instructors, resume the studio's pedagogy and do a brief discussion of the process and progress of this year's work in King
Nuworsoo, Cornelius, Topping, Kenneth
exaly +4 more sources
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Molecular Immunology, 2003
Monoclonal antibodies (mAbs) are being increasingly used in cancer therapy owing to their ability to recognize specifically cancer cells and to activate complement- and cell-mediated cytotoxicity and/or to induce growth arrest or apoptosis. The therapeutic potential of anticancer antibodies is significantly limited due to the ability of cancer cells to
Z, Fishelson +4 more
openaire +2 more sources
Monoclonal antibodies (mAbs) are being increasingly used in cancer therapy owing to their ability to recognize specifically cancer cells and to activate complement- and cell-mediated cytotoxicity and/or to induce growth arrest or apoptosis. The therapeutic potential of anticancer antibodies is significantly limited due to the ability of cancer cells to
Z, Fishelson +4 more
openaire +2 more sources
European Radiology, 2020
(1) To assess the visibility and diameters of the thoracic duct (TD) and cisterna chyli (CC) on MR cholangiopancreatography (MRCP) in children. (2) To evaluate for the presence of any lymphatic abnormalities and assess their association with diseases in which the immune system is implicated in etiopathogenesis.This retrospective study included 142 ...
Ebtehaj AlShehri +3 more
openaire +2 more sources
(1) To assess the visibility and diameters of the thoracic duct (TD) and cisterna chyli (CC) on MR cholangiopancreatography (MRCP) in children. (2) To evaluate for the presence of any lymphatic abnormalities and assess their association with diseases in which the immune system is implicated in etiopathogenesis.This retrospective study included 142 ...
Ebtehaj AlShehri +3 more
openaire +2 more sources
Journal of Clinical Oncology, 2023
e15641 Background: Tumor-promoting inflammation is an established hallmark of cancer. C-reactive protein (CRP) is one of the most studied negative prognostic markers of the systemic inflammatory response (SIR) and known to be implicated in detrimental immune responses. Circulating CRP, as measured in routine practice, is a pentameric structure (pCRP).
Anniken Joerlo Fuglestad +6 more
openaire +1 more source
e15641 Background: Tumor-promoting inflammation is an established hallmark of cancer. C-reactive protein (CRP) is one of the most studied negative prognostic markers of the systemic inflammatory response (SIR) and known to be implicated in detrimental immune responses. Circulating CRP, as measured in routine practice, is a pentameric structure (pCRP).
Anniken Joerlo Fuglestad +6 more
openaire +1 more source
Human Immunology, 2012 Autoantibodies against modified C-reactive protein (mCRP) are frequently found in patients with lupus nephritis and are associated with disease activity, suggesting their pathogenic role in lupus nephritis.
Ying Tan, Feng Yu, Ming-Hui Zhao
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