Results 251 to 260 of about 692,269 (276)

Discovery of RG7112: A Small-Molecule MDM2 Inhibitor in Clinical Development

ACS Medicinal Chemistry Letters, 2013
Kathryn Packman, Lyubomir Vassilev, Christian Tovar   +2 more
exaly  

INTERMITTENT DOSING OF MDM2 INHIBITOR

2015
FERRETTI STEPHANE, JEAY SEBASTIEN
openaire   +3 more sources

Discovery of a new small-molecule inhibitor of p53–MDM2 interaction using a yeast-based approach

Biochemical Pharmacology, 2013
Yari Ciribilli, Andreia Palmeira, Miguel X Fernandes   +2 more
exaly  

Modulation of the p53/MDM2 interplay by HAUSP inhibitors

Journal of Molecular Cell Biology, 2017
Omid Tavana, Wei Gu
exaly  

Discovery of dihydroisoquinolinone derivatives as novel inhibitors of the p53–MDM2 interaction with a distinct binding mode

Bioorganic and Medicinal Chemistry Letters, 2015
Sebastien Jeay, Patrick Chène, Joerg Kallen   +2 more
exaly  

The central valine concept provides an entry in a new class of non peptide inhibitors of the p53–MDM2 interaction

Bioorganic and Medicinal Chemistry Letters, 2012
Patrick Chène, Joerg Kallen, Pascal Furet   +2 more
exaly  

Inhibitors of the interaction between MDM2 and P53

2010
PONCELET VIRGINIE SOPHIE, COUPA SOPHIE, STORCK PIERRE-HENRI, SCHOENTJES BRUNO   +3 more
openaire   +6 more sources

Small-Molecule Inhibitors of the MDM2–p53 Protein–Protein Interaction (MDM2 Inhibitors) in Clinical Trials for Cancer Treatment

Journal of Medicinal Chemistry, 2015
Denzil Bernard, Shaomeng Wang, Yu-Jun Zhao   +2 more
exaly  

Patented small molecule inhibitors of p53–MDM2 interaction

Expert Opinion on Therapeutic Patents, 2006
Nouri Neamati, Raveendra Dayam, Jinxia Deng   +2 more
exaly  

Fluorescence polarization assay and inhibitor design for MDM2/p53 interaction

Analytical Biochemistry, 2004
Rumin Zhang, Yaolin Wang, William Windsor   +2 more
exaly