Results 11 to 20 of about 10,083 (200)
Reported Cases of Serotonin Syndrome in MDMA Users in FAERS Database
Frontiers in Psychiatry, 2022 3,4-Methylenedioxymethamphetamine (MDMA), is investigated as a treatment for post-traumatic stress disorder and other anxiety-related conditions in multiple placebo-controlled and open label studies. MDMA-assisted therapy is projected for approval by the
Tigran Makunts +4 more
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Journal of Education, Health and Sport, 2023 Introduction: Post-traumatic stress disorder (PTSD) is a common health issue of complex etiology significantly deteriorating functioning in everyday life. It may develop as a result of exposure to traumatic events like traffic accidents, war experience,
Karol Womperski +6 more
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Duloxetine inhibits effects of MDMA ("ecstasy") in vitro and in humans in a randomized placebo-controlled laboratory study. [PDF]
PLoS ONE, 2012 This study assessed the effects of the serotonin (5-HT) and norepinephrine (NE) transporter inhibitor duloxetine on the effects of 3,4-methylenedioxy-methamphetamine (MDMA, ecstasy) in vitro and in 16 healthy subjects.
Cédric M Hysek +9 more
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A review on the mitochondrial toxicity of “ecstasy” (3,4-methylenedioxymethamphetamine, MDMA)
Current Research in Toxicology, 2022 3,4-Methylenedioxymethamphetamine (MDMA or “ecstasy”) is a drug of abuse used by millions worldwide. MDMA human abuse and dependence is well described, but addictive properties are not always consistent among studies. This amphetamine is a substrate type
João Paulo Capela, Félix Dias Carvalho
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Frontiers in Pharmacology, 2019 The entactogen MDMA (3,4-methylenedioxy-methamphetamine, “Ecstasy”) exerts its psychotropic effects acting primarily as a substrate of the serotonin transporter (SERT) to induce a non-exocytotic release of serotonin.
Patricio Sáez-Briones +6 more
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Journal of Neuroinflammation, 2011 Background 3,4-Methylenedioxymethamphetamine (MDMA) produces a neuroinflammatory reaction in rat brain characterized by an increase in interleukin-1 beta (IL-1β) and microglial activation.
O'Shea Esther +5 more
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A Review of 3,4-methylenedioxymethamphetamine (MDMA)-Assisted Psychotherapy
Frontiers in Psychiatry, 2019 This paper provides a brief review of the history, proposed pharmacological mechanisms, safety issues, and clinical applications of the medicine 3,4-methylenedioxymethamphetamine (MDMA). Most clinical MDMA research in patients to date has focused on MDMA-
Ben Sessa, Laurie Higbed, David Nutt
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Frontiers in Psychiatry, 2023 Introduction3,4-methylenedioxymethamphetamine-assisted therapy (MDMA-AT) for post-traumatic stress disorder (PTSD) has demonstrated promise in multiple clinical trials.
S. Parker Singleton +15 more
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Zinc Protects against MDMA-Induced Apoptosis of Sertoli Cells in Mouse via Attenuation of Caspase-3 [PDF]
International Journal of Fertility and Sterility, 2020 Background: 3,4-Methylenedioxymethamphetamine (MDMA) disrupts function of the endocrine system and differentorgans such as heart, blood vessels, kidney, liver and nervous systems.
Nadia Hossein-Zadeh +4 more
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The Identification of a Chlorinated MDMA [PDF]
Journal of Analytical Toxicology, 2005 The abuse of the designer amphetamines such as 3,4-methylenedioxymethamphetamine (MDMA) is increasing throughout the world. They have become popular drugs at all night techno dance parties, and their detection is an important issue. The objective of the presented study was to identify an unknown compound detected by thin-layer chromatography (TLC) in ...
V, Maresova +5 more
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