Results 21 to 30 of about 33,449 (240)

A Review of 3,4-methylenedioxymethamphetamine (MDMA)-Assisted Psychotherapy

open access: yesFrontiers in Psychiatry, 2019
This paper provides a brief review of the history, proposed pharmacological mechanisms, safety issues, and clinical applications of the medicine 3,4-methylenedioxymethamphetamine (MDMA). Most clinical MDMA research in patients to date has focused on MDMA-
Ben Sessa, Laurie Higbed, David Nutt
doaj   +1 more source

ERP evidence suggests executive dysfunction in ecstasy polydrug users [PDF]

open access: yes, 2013
Background: Deficits in executive functions such as access to semantic/long-term memory have been shown in ecstasy users in previous research. Equally, there have been many reports of equivocal findings in this area.
A Gamma   +53 more
core   +1 more source

Changes in interleukin-1 signal modulators induced by 3,4-methylenedioxymethamphetamine (MDMA): regulation by CB2 receptors and implications for neurotoxicity

open access: yesJournal of Neuroinflammation, 2011
Background 3,4-Methylenedioxymethamphetamine (MDMA) produces a neuroinflammatory reaction in rat brain characterized by an increase in interleukin-1 beta (IL-1β) and microglial activation.
O'Shea Esther   +5 more
doaj   +1 more source

Neurotoxicity induced by mephedrone: an up-to-date review [PDF]

open access: yes, 2017
BACKGROUND: Mephedrone is a β-ketoamphetamine belonging to the family of synthetic cathinones, an emerging class of designer drugs known for their hallucinogenic and psychostimulant properties as well as for their abuse potential.
Busardo', FRANCESCO PAOLO   +6 more
core   +1 more source

Have Halpern et al. (2004) detected 'residual neuropsychological effects' of MDMA? Not likely [PDF]

open access: yes, 2004
[Extract] The preliminary study by Halpern et al. (2004) is a commendable attempt to isolate correlates of ‘Ecstasy’ use from some of the many confounds that have plagued previous work on this controversial issue. However, Halpern et al.
Hasking, Penelope, Lyvers, Michael
core   +1 more source

Direct and long-lasting effects elicited by repeated drug administration on 50-kHz ultrasonic vocalizations are regulated differently: Implications for the study of the affective properties of drugs of abuse [PDF]

open access: yes, 2013
Several studies suggest that 50-kHz ultrasonic vocalizations (USVs) may indicate a positive affective state in rats, and these vocalizations are increasingly being used to investigate the properties of psychoactive drugs.
FRAU L   +3 more
core   +1 more source

Protective effect of pentoxifylline on male Wistar rat testicular germ cell apoptosis induced by 3,4-methylenedioxymeth amphetamine [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2016
Objective(s): 3, 4-methylenedioxymethamphetamine (MDMA) one of the methamphetamine derivatives that affect the reproductive system, has not been well understood.
Mahnaz Nouri   +4 more
doaj  

MDMA-assisted psychotherapy for people diagnosed with treatment-resistant PTSD: what it is and what it isn’t

open access: yesAnnals of General Psychiatry, 2020
Background PTSD is a chronic condition with high rates of comorbidity, but current treatment options are limited and not always effective. One novel approach is MDMA-assisted psychotherapy for people diagnosed with treatment-resistant PTSD, where MDMA is
Louise Morgan
doaj   +1 more source

A review on the mitochondrial toxicity of “ecstasy” (3,4-methylenedioxymethamphetamine, MDMA)

open access: yesCurrent Research in Toxicology, 2022
3,4-Methylenedioxymethamphetamine (MDMA or “ecstasy”) is a drug of abuse used by millions worldwide. MDMA human abuse and dependence is well described, but addictive properties are not always consistent among studies. This amphetamine is a substrate type
João Paulo Capela, Félix Dias Carvalho
doaj   +1 more source

Evidence for selective executive function deficits in ecstasy/polydrug users [PDF]

open access: yes, 2009
Previous research has suggested that the separate aspects of executive functioning are differentially affected by ecstasy use. Although the inhibition process appears to be unaffected by ecstasy use, it is unclear whether this is true of heavy users ...
Fisk, John, Montgomery, C.
core   +1 more source

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