Results 21 to 30 of about 15,040 (247)

MDMA enhances emotional empathy and prosocial behavior [PDF]

, 2013
3,4-Methylenedioxymethamphetamine (MDMA, 'ecstasy') releases serotonin and norepinephrine. MDMA is reported to produce empathogenic and prosocial feelings. It is unknown whether MDMA in fact alters empathic concern and prosocial behavior. We investigated
Heinrichs, M., Liechti, M. E., Preller, K H, Schmid, Yasmin, Liechti, M E, Simmler, L. D., Preller, Katrin H., Domes, Gregor, Heinrichs, Markus, Domes, G., Boris B. Quednow, Eisenegger, C., Gregor Domes, Quednow, Boris B; https://orcid.org/, Markus Heinrichs, Schmid, Y, Yasmin Schmid, Linda D. Simmler, Liechti, Matthias E., Simmler, Linda D., Preller, K. H., Cédric M. Hysek, Hysek, Cédric M., Christoph Eisenegger, Katrin H. Preller, Hysek, C. M., Domes, G, Heinrichs, M, Eisenegger, Christoph, Schmid, Y., Quednow, Boris B., Matthias E. Liechti, Hysek, C M, Simmler, L D, Eisenegger, C, Quednow, B. B.   +35 more
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Reported Cases of Serotonin Syndrome in MDMA Users in FAERS Database

Frontiers in Psychiatry, 2022
3,4-Methylenedioxymethamphetamine (MDMA), is investigated as a treatment for post-traumatic stress disorder and other anxiety-related conditions in multiple placebo-controlled and open label studies. MDMA-assisted therapy is projected for approval by the
Tigran Makunts, Tigran Makunts, Lisa Jerome, Ruben Abagyan, Alberdina de Boer   +4 more
doaj   +1 more source

Ecstasy/MDMA attributed problems reported by novice, moderate and heavy recreational users [PDF]

, 2002
The recreational use of MDMA/Ecstasy (3,4-methylenedioxymethamphetamine) is associated with many psychobiological problems, but there is a paucity of data on how these relate to the level of past use.
Buchanan, Tom, Scholey, Andrew, Parrott, A.C., Heffernan, T., Ling, J., Heffernan, Tom, Parrott, Andrew, Scholey, A.B., Rodgers, J., Ling, Jonathan, Rodgers, Jacqui, Buchanan, T.   +11 more
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Effects of acute MDMA intoxication on mood and impulsivity: role of the 5-HT2 and 5-HT1 receptors. [PDF]

PLoS ONE, 2012
UNLABELLED: MDMA induces positive mood and increases impulse control during intoxication, but only a few studies on the neuropharmacological mechanisms underlying these processes have been conducted. It was hypothesized that pretreatment with 5-HT(1) and
Janelle H P van Wel, Kim P C Kuypers, Eef L Theunissen, Wendy M Bosker, Katja Bakker, Johannes G Ramaekers   +5 more
doaj   +1 more source

Differential effects of MDMA and methylphenidate on social cognition. [PDF]

, 2014
Social cognition is important in everyday-life social interactions. The social cognitive effects of 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') and methylphenidate (both used for neuroenhancement and as party drugs) are largely unknown.
Liechti, ME, Boris B Quednow, Hysek, Cédric M., Molly J Crockett, Crockett, Molly, Schmid, Yasmin, Cédric M Hysek, Hysek, CM, Linda D Simmler, Crockett, MJ, Simmler, LD, Schmid, Y, Quednow, Boris B., Yasmin Schmid, Liechti, Matthias E., Quednow, BB, Simmler, Linda D., Matthias E Liechti, Crockett, Molly J.   +18 more
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Duloxetine inhibits effects of MDMA ("ecstasy") in vitro and in humans in a randomized placebo-controlled laboratory study. [PDF]

PLoS ONE, 2012
This study assessed the effects of the serotonin (5-HT) and norepinephrine (NE) transporter inhibitor duloxetine on the effects of 3,4-methylenedioxy-methamphetamine (MDMA, ecstasy) in vitro and in 16 healthy subjects.
Cédric M Hysek, Linda D Simmler, Valentina G Nicola, Nerina Vischer, Massimiliano Donzelli, Stephan Krähenbühl, Eric Grouzmann, Jörg Huwyler, Marius C Hoener, Matthias E Liechti   +9 more
doaj   +1 more source

Sex differences in the effects of MDMA (ecstasy) on plasma copeptin in healthy subjects [PDF]

, 2011
BACKGROUND:3,4-Methylenedioxymethamphetamine (MDMA, ecstasy) misuse is associated with hyponatremia particularly in women. Hyponatremia is possibly due to inappropriate secretion of plasma arginine vasopressin (AVP).
Liechti, M. E., Cédric M. Hysek, Hysek, C. M., Matthias E. Liechti, Linda D. Simmler, Simmler, L. D.   +5 more
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The use of 3,4-Methylenedioxymethamphetamine (MDMA) in the treatment of Post-Traumatic Stress Disorder (PTSD) - review

Journal of Education, Health and Sport, 2023
Introduction: Post-traumatic stress disorder (PTSD) is a common health issue of complex etiology significantly deteriorating functioning in everyday life. It may develop as a result of exposure to traumatic events like traffic accidents, war experience,
Karol Womperski, Rafał Bogacz, Magdalena Gaik, Inga Magda, Justyna Woźniak, Ewa Uram, Magdalena Osuch   +6 more
doaj   +1 more source

Impact of cytochrome P450 2D6 function on the chiral blood plasma pharmacokinetics of 3,4-methylenedioxymethamphetamine (MDMA) and its phase I and II metabolites in humans [PDF]

, 2016
3,4-methylenedioxymethamphetamine (MDMA; ecstasy) metabolism is known to be stereoselective, with preference for S-stereoisomers. Its major metabolic step involves CYP2D6-catalyzed demethylenation to 3,4-dihydroxymethamphetamine (DHMA), followed by ...
Tingelhoff, Eva H., Eva H. Tingelhoff, Schmidhauser, Corina, Steuer, Andrea E, Yasmin Schmid (3181563), Eva H. Tingelhoff (3181572), Schmid, Yasmin, Tingelhoff, Eva H, Andrea E. Steuer (1712023), Anna Rickli (3181569), Yasmin Schmid, Anna Rickli, Thomas Kraemer (271037), Liechti, Matthias E., Matthias E Liechti, Liechti, Matthias E, Corina Schmidhauser, Andrea E. Steuer, Rickli, Anna, Matthias E. Liechti (166584), Eva H Tingelhoff, Thomas Kraemer, Andrea E Steuer, Corina Schmidhauser (3181566), Steuer, Andrea E., Matthias E. Liechti, Kraemer, Thomas   +26 more
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Effects of methylphenidate and MDMA on appraisal of erotic stimuli and intimate relationships [PDF]

, 2015
Methylphenidate mainly enhances dopamine neurotransmission whereas 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") mainly enhances serotonin neurotransmission.
Hysek, Cédric M, Rogers, Robert D., Hysek, Cédric M., Bosch, Oliver G, Liechti, Matthias E, Preller, Katrin H, Schmid, Yasmin, Preller, Katrin H., Bosch, Oliver G., Bilderbeck, Amy C., Quednow, Boris B; https://orcid.org/, Quednow, Boris B., Schmid, Y, Liechti, Matthias E., Bilderbeck, A C, Rogers, R D   +15 more
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