Results 41 to 50 of about 15,040 (247)

Protective effect of pentoxifylline on male Wistar rat testicular germ cell apoptosis induced by 3,4-methylenedioxymeth amphetamine [PDF]

Iranian Journal of Basic Medical Sciences, 2016
Objective(s): 3, 4-methylenedioxymethamphetamine (MDMA) one of the methamphetamine derivatives that affect the reproductive system, has not been well understood.
Mahnaz Nouri, Shabnam Movassaghi, Alireza foroumadi, Mansooreh Soleimani, Zahra Nadia Sharifi   +4 more
doaj  

Effects of 3,4-Methylenedioxymethamphetamine on Conditioned Fear Extinction and Retention in a Crossover Study in Healthy Subjects

Frontiers in Pharmacology, 2022
Background: 3,4-Methylenedioxymethamphetamine (MDMA) has shown initial promise as an adjunct in psychotherapy to treat posttraumatic stress disorder (PTSD). Its efficacy and safety have been demonstrated across phase I–III studies. However, the mechanism
Patrick Vizeli, Patrick Vizeli, Patrick Vizeli, Isabelle Straumann, Isabelle Straumann, Urs Duthaler, Urs Duthaler, Nimmy Varghese, Nimmy Varghese, Anne Eckert, Anne Eckert, Martin P. Paulus, Victoria Risbrough, Victoria Risbrough, Matthias E. Liechti, Matthias E. Liechti   +15 more
doaj   +1 more source

MDMA /// Beyond ecstasy [PDF]

For nearly 40 years, MDMA has been used as a party drug in the Netherlands. Today, more than one in 10 people have used this prohibited substance at least once.
de Jonge, Martha, Kolthoff, Emile, Zandstra, Philippus, Toebes, Brigit; id_orcid, van den Brink, Wim, Gresnigt, Femke, Vermetten, Eric, De Cock, Ward   +7 more
core   +3 more sources

Increased interleukin-1β levels following low dose MDMA induces tolerance against the 5-HT neurotoxicity produced by challenge MDMA

Journal of Neuroinflammation, 2011
Background Preconditioning is a phenomenon by which tolerance develops to injury by previous exposure to a stressor of mild severity. Previous studies have shown that single or repeated low dose MDMA can attenuate 5-HT transporter loss produced by a ...
Mayado Andrea, Torres Elisa, Gutierrez-Lopez Maria D, Colado Maria I, O'Shea Esther   +4 more
doaj   +1 more source

MDMA-assisted therapy costs by component; Total: $11,537 per patient.

, 2022
MDMA-assisted therapy costs by component; Total: $11,537 per patient.
Jennifer M. Mitchell (12153056), James G. Kahn (7444547), Elliot Marseille (54691)   +2 more
core   +1 more source

Oxytocin receptor gene variations and socio-emotional effects of MDMA: A pooled analysis of controlled studies in healthy subjects.

PLoS ONE, 2018
Methylenedioxymethamphetamine (MDMA) increases oxytocin, empathy, and prosociality. Oxytocin plays a critical role in emotion processing and social behavior and has been shown to mediate the prosocial effects of MDMA in animals. Genetic variants, such as
Patrick Vizeli, Matthias E Liechti
doaj   +1 more source

Pharmacology of amphetamine-type designer drugs [PDF]

, 2013
In this thesis project, we studied the pharmacology of long-known psychostimulants and of novel amphetamine-type designer drugs in vitro. On the basis of the pharmacological characterization, we focused on the drug effects in humans, investigating the ...
Simmler, Linda
core   +1 more source

Acute toxicity of ADB‐CHMINACA ‐ a case series of patients with pronounced central nervous symptoms including the posterior reversible encephalopathic syndrome

British Journal of Clinical Pharmacology, EarlyView.
Aim This report presents a series of 16 patients who were admitted to the emergency department following confirmed intake of the potent synthetic cannabinoid ADB‐CHMINACA. Methods The cases are drawn from a prospective observational study following the recreational use of synthetic cannabinoids.
Maren Hermanns‐Clausen, Michaela Sommer, Annette Zschiesche, Verena Angerer, Martin Scheu, Florian Eyer, Johannes Nadler, Volker Auwärter   +7 more
wiley   +1 more source

Exploring new avenues: Psychedelic‐assisted therapy for young people

British Journal of Clinical Pharmacology, EarlyView.
Rates of mental illness in young people are increasing, whereas the development of novel mental health treatments has not significantly progressed. Psychedelic‐assisted therapy, using substances such as psilocybin and 3,4‐methylenedioxymethamphetamine (MDMA), has shown potential in the treatment of mental illnesses in the adult population, including ...
Ioanna Artemis Vamvakopoulou, Dasha Nicholls, David J. Nutt, Martina Di Simplicio   +3 more
wiley   +1 more source

Rapport Denktank MDMA Beleid: Ontwikkeling van een rationeel nationaal MDMA-beleid met behulp van multi-decision multi-criterion decision analyse (MD-MCDA) [ Report MDMA Policy Think Tank: Development of a rational national MDMA policy using multi decision multi criterion decision analysis (MDMCDA) ]

, 2020
In the Netherlands, ecstasy (MDMA, 3,4-methylenedioxy-methamphetamine) is a widely used drug with about 370,000 last year users. The Netherlands is also an important export country for MDMA.
Stuurgroep Denktank MDMA Beleid
core   +1 more source