Results 61 to 70 of about 33,449 (240)

Integrating the Gestalt Model of Self With Psychedelic‐Assisted Psychotherapy

The Journal of Humanistic Counseling, EarlyView.
ABSTRACT This theoretical integration paper employs a conceptual analysis methodology to synthesize the Gestalt model of self‐as‐process with Psychedelic Somatic Interactional Psychotherapy (PSIP). Unlike traditional psychedelic therapy models that defer therapeutic engagement to postsession integration, PSIP emphasizes an active, directive therapeutic
Travis R. Fox
wiley   +1 more source

Improving drug identification in overdose death surveillance by using clinical natural language processing models

Journal of Forensic Sciences, EarlyView.
Abstract The rising rate of drug‐related deaths in the United States, largely driven by fentanyl, requires timely and accurate surveillance. However, critical overdose data are often buried in free‐text coroner reports, leading to delays and information loss when coded into ICD (International Classification of Disease)‐10 classifications.
Arthur J. Funnell, Panayiotis Petousis, Fabrice Harel‐Canada, Ruby Romero, Alex A. T. Bui, Adam Koncsol, Hritika Chaturvedi, Chelsea Shover, David Goodman‐Meza   +8 more
wiley   +1 more source

Protective Effects of N-Acetyl-L-cystein on 3,4-Methylene Dioxymethamphetamie-Induced Neurotoxicity in Cerebellum of Male Rats

Basic and Clinical Neuroscience, 2011
Introduction: 3-4, methylenedioxymethamphetamine (MDMA) causes apoptosis in nervous system and several studies suggest that oxidative stress contributes to MDMA-induced neurotoxicity. The aim of this study is to examine the effects of N-acetyl-L-Cystein (
Sara Soleimani Asl, Peiman Falahati, Nima shekar riz, Nima Molavi, Farzaneh Esmaeili, Zahra Azimi, Freidoon Sajadi, Parisa Hayat, Alireza Samzadeh-Kermani, Mehdi Mehdizadeh   +9 more
doaj   +2 more sources

Pharmacogenetics of ecstasy: CYP1A2, CYP2C19, and CYP2B6 polymorphisms moderate pharmacokinetics of MDMA in healthy subjects [PDF]

, 2017
In vitro studies showed that CYP2C19, CYP2B6, and CYP1A2 contribute to the metabolism of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) to 3,4-methylenedioxyamphetamine (MDA).
Liechti, Matthias E., Meyer Zu Schwabedissen, Henriette E., Prestin, Katharina, Schmid, Yasmin, Vizeli, Patrick   +4 more
core   +1 more source

Trends in toxicological findings and drug seizures of MDMA in New Zealand from 2010 to 2022

Journal of Forensic Sciences, EarlyView.
Abstract 3,4‐Methylenedioxymethamphetamine (MDMA) or “ecstasy,” is a commonly used drug worldwide, including in New Zealand, where 4.8% of the population aged 15 years or over reported using it in a 2023/2024 survey. This study provides additional insights on MDMA prevalence data in New Zealand by reporting toxicology data from Coronial and driving ...
Thomas J. Sheehan, Hilary J. Hamnett, Sarah G. G. Russell, Diana Kappatos, Helen Poulsen   +4 more
wiley   +1 more source

Insights from a six‐year hair drug analysis compendium in drug‐facilitated crimes involving vulnerable population cases

Journal of Forensic Sciences, EarlyView.
Abstract Hair analysis is a well‐established matrix in forensic toxicology, offering a valuable alternative or complement to traditional matrices in diverse contexts, including drug‐facilitated crimes (DFC), elder abuse, and accidental exposure in children.
Amandine Fort, Coralie Boudin, Hélène Eysseric‐Guerin, Virginie Scolan, François Paysant, Cloé Scherpereel, Mélissa Revet, Françoise Stanke‐Labesque, Théo Willeman   +8 more
wiley   +1 more source

Acute and long-term effects of a single dose of MDMA on aggression in Dark Agouti rats [PDF]

, 2018
MDMA causes selective depletion of serotonergic terminals in experimental animals and the consequent decrease in synaptic 5-HT may, inter alia, increase impulsivity. To study the effects of MDMA upon brain function, the behaviour of male Dark Agouti rats
Andó Rómeó, Bagd, György, Benko A, Ferrington L, Kelly PAT, Kirilly Eszter   +5 more
core   +1 more source

Insights from a 6‐year hair drug analysis compendium in drug‐facilitated sexual assault cases

Journal of Forensic Sciences, EarlyView.
Abstract Drug‐facilitated sexual assault (DFSA) may involve a diverse array of substances, including illicit drugs, prescription medications, and over‐the‐counter pharmaceuticals. Hair analysis has emerged as a valuable forensic tool, offering an extended window of detection spanning several months. However, interpreting drug concentrations in hair can
Amandine Fort, Coralie Boudin, Hélène Eysseric‐Guerin, Virginie Scolan, Jérémy Borges, François Chiron, Pierre Henry, Françoise Stanke‐Labesque, Théo Willeman   +8 more
wiley   +1 more source

Zingiber Officinale Alters 3,4-methylenedioxymethamphetamine-Induced Neurotoxicity in Rat Brain [PDF]

Cell Journal, 2012
Objective: The spice Zingiber officinale or ginger possesses antioxidant activity and neuroprotective effects. The effects of this traditional herbal medicine on 3,4-methylenedioxymethamphetamine (MDMA) induced neurotoxicity have not yet been studied ...
Mehdi Mehdizadeh, Fataneh Dabaghian, Akram Nejhadi, Hassan Fallah-huseini, Samira Choopani, Nima Shekarriz, Nima Molavi, Arghavan Basirat, Farzaneh Mohammadzadeh Kazorgah, Alireza Samzadeh-Kermani, Sara Soleimani Asl   +10 more
doaj  

Psychedelic‐assisted treatment for substance use disorder: A narrative systematic review

Addiction, EarlyView.
Abstract Background and aims This is the first systematic review of the extant literature on all major psychedelic‐assisted treatment for alcohol use disorder (AUD), tobacco use disorder (TUD) and other substance use disorders (SUD). We aimed to summarise the evidence for efficacy of psychedelic‐assisted treatment for AUD, TUD, and SUD; to evaluate its
Theodore Piper, Francesca Small, Sam Brown, Michael Kelleher, Luke Mitcheson, James Rucker, Allan H. Young, John Marsden   +7 more
wiley   +1 more source