Results 51 to 60 of about 10,083 (200)

From emergence to replacement: The evolution of 3‐methylmethcathinone (3‐MMC) and its substitutes in the Dutch drug market (2012–2024)

Addiction, EarlyView.
Abstract Background and aims The market for new psychoactive substances (NPS) is highly dynamic, with hundreds of substances emerging on the European drug market in the last decade. 3‐methylmethcathinone (3‐MMC), a synthetic cathinone and isomer of mephedrone (4‐MMC), gained popularity in the Netherlands due to its psychostimulant effects and initial ...
Nadia Robert Petronella Wilhelmina Hutten, Pieter Edmond Oomen, Frederiek Schutten, Margriet Walburga van Laar, Laura Alexandra Smit‐Rigter   +4 more
wiley   +1 more source

On 3‐MMC: A Cathinone I Have Come to Know and Love

Anthropology of Consciousness, EarlyView.
ABSTRACT This article attempts to complicate the mythology of a compound in a state of becoming. I will trace lightly its origins as a cultural disruptor and how I am implicated in this imperative. Introducing you to 3‐MMC will require multiple modes of storytelling and taking of liberties, drawing on literature reviews, practice‐based research, prose,
Carmen Ostrander
wiley   +1 more source

Motives for MDMA Use: A Comparative Study with Alcohol and Cannabis

European Psychiatry
Introduction While research on drug use motives has primarily focused on widely used substances like alcohol, tobacco, and cannabis, understanding the motivations behind MDMA use is crucial for developing targeted therapeutic, preventive, and harm ...
D. Zullino, L. Penzenstadler, S. Rothen, F. Seragnnoli, A. S. Girardet, G. Calzada, G. Thorens   +6 more
doaj   +1 more source

The ameliorating effects of Vitamin E on hepatotoxicity of ecstasy

Journal of Research in Medical Sciences, 2020
Background: The production of stress oxidative condition in body which is caused by consumption of ecstasy (3,4-methylenedioxymethamphetamine [MDMA]) leads to a liver damage.
Masoumeh Zirak Javanmard, Khadije Meghrazi, Sayed Soran Ghafori, Mojtaba Karimipour   +3 more
doaj   +1 more source

Safety pharmacology of acute mescaline administration in healthy participants

British Journal of Clinical Pharmacology, EarlyView.
Aims Psychedelics, including mescaline, may serve as novel treatments for depression and anxiety. However, data is scarce on the safety of mescaline. Methods The present pooled analysis included two double‐blind, randomized, placebo‐controlled studies with a total of 48 participants and 96 mescaline administrations. Single oral‐dose administrations (n =
Aaron Klaiber, Mélusine Humbert‐Droz, Laura Ley, Yasmin Schmid, Matthias E. Liechti   +4 more
wiley   +1 more source

Pharmacogenomics of 3,4-Methylenedioxymethamphetamine (MDMA): A Narrative Review of the Literature

Pharmaceutics
3,4-Methylenedioxymethamphetamine (MDMA) is a synthetic amphetamine derivative with notable psychoactive properties and emerging therapeutic potential, particularly for treating post-traumatic stress disorders (PTSD) and substance use disorders. However,
Guillaume Drevin, Maria Pena-Martin, Aurélien Bauduin, Antoine Baudriller, Marie Briet, Chadi Abbara   +5 more
doaj   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Comprehensive in vitro profiling of traditional and emerging stimulants at monoamine transporters and the 5‐HT2A receptor

British Journal of Pharmacology, EarlyView.
A pharmacological profiling of 58 synthetic stimulants of various classes at dopamine, norepinephrine, and serotonin transporters and the 5‐HT2A receptor, most showing distinct class‐dependent profiles, with some indicating a high abuse potential. Background and Purpose New psychoactive substances (NPSs) often emerge on the illicit drug market with ...
Darta Stalberga, Robert Kronstrand, Bianca Schranz, Nick van Zijl, Sebastian Karlman, Soma Aref, Tobias Rautio, Svante Vikingsson, Mattias Persson, Henrik Green   +9 more
wiley   +1 more source

The Role of Religious Belief and Sentencing Decisions in a UK Sample

Journal of Personality, EarlyView.
ABSTRACT Objective This is a stage 1 registered report submission that seeks to examine whether religious belief and a range of other individual differences variables are associated with youth justice preferences. Method As this is a stage 1 registered report, these are liable to change.
Isaac Halstead, Alex Lloyd
wiley   +1 more source

“They need to get a new program”: Experiential frictions with the gender of care in the 12 step program for ethnically Mexican women

Medical Anthropology Quarterly, EarlyView.
Abstract Using gender as an analytic, I parse out how the historical gendered, classed, and racialized roots of the 12 Step Program remain present in its therapeutic model, even in global contexts beyond its original formulation. These foundations continue to shape therapeutic logics and experience within the Program, in positive and negative ways.
Ellen E. Kozelka
wiley   +1 more source