Results 31 to 40 of about 15,040 (247)
Frontiers in Pharmacology, 2019 The entactogen MDMA (3,4-methylenedioxy-methamphetamine, “Ecstasy”) exerts its psychotropic effects acting primarily as a substrate of the serotonin transporter (SERT) to induce a non-exocytotic release of serotonin.
Patricio Sáez-Briones +6 more
doaj +1 more source
A review on the mitochondrial toxicity of “ecstasy” (3,4-methylenedioxymethamphetamine, MDMA)
Current Research in Toxicology, 2022 3,4-Methylenedioxymethamphetamine (MDMA or “ecstasy”) is a drug of abuse used by millions worldwide. MDMA human abuse and dependence is well described, but addictive properties are not always consistent among studies. This amphetamine is a substrate type
João Paulo Capela, Félix Dias Carvalho
doaj +1 more source
Carvedilol inhibits the cardiostimulant and thermogenic effects of MDMA in humans : lost in translation [PDF]
, 2013 We greatly appreciate the comments offered by Drs Rolle, Takematsu, and Hoffman and the opportunity to put our work into a wider perspective. We share the view that our work does not reflect the clinical situation but rather provides a proof of mechanism
Liechti, M. E. +7 more
core +1 more source
Development of a high-speed MALDI-triple quadrupole mass spectrometric method for the determination of 3,4-methylenedioxymethamphetamine (MDMA) in oral fluid [PDF]
, 2016 3,4-Methylenedioxymethamphetamine (MDMA, ecstasy) is still a widely used illicit designer drug and its detection in different matrices is of major importance for forensic purposes (e.g.
Hysek, Cédric M +12 more
core +1 more source
Journal of Neuroinflammation, 2011 Background 3,4-Methylenedioxymethamphetamine (MDMA) produces a neuroinflammatory reaction in rat brain characterized by an increase in interleukin-1 beta (IL-1β) and microglial activation.
O'Shea Esther +5 more
doaj +1 more source
The Identification of a Chlorinated MDMA [PDF]
Journal of Analytical Toxicology, 2005 The abuse of the designer amphetamines such as 3,4-methylenedioxymethamphetamine (MDMA) is increasing throughout the world. They have become popular drugs at all night techno dance parties, and their detection is an important issue. The objective of the presented study was to identify an unknown compound detected by thin-layer chromatography (TLC) in ...
V, Maresova +5 more
openaire +2 more sources
Frontiers in Psychiatry, 2023 Introduction3,4-methylenedioxymethamphetamine-assisted therapy (MDMA-AT) for post-traumatic stress disorder (PTSD) has demonstrated promise in multiple clinical trials.
S. Parker Singleton +15 more
doaj +1 more source
Annals of General Psychiatry, 2020 Background PTSD is a chronic condition with high rates of comorbidity, but current treatment options are limited and not always effective. One novel approach is MDMA-assisted psychotherapy for people diagnosed with treatment-resistant PTSD, where MDMA is
Louise Morgan
doaj +1 more source
Non-Serotonergic Neurotoxicity by MDMA (Ecstasy) in Neurons Derived from Mouse P19 Embryonal Carcinoma Cells. [PDF]
PLoS ONE, 2016 3,4-methylenedioxymethamphetamine (MDMA; ecstasy) is a commonly abused recreational drug that causes neurotoxic effects in both humans and animals. The mechanism behind MDMA-induced neurotoxicity is suggested to be species-dependent and needs to be ...
Dina Popova +3 more
doaj +1 more source
Zinc Protects against MDMA-Induced Apoptosis of Sertoli Cells in Mouse via Attenuation of Caspase-3 [PDF]
International Journal of Fertility and Sterility, 2020 Background: 3,4-Methylenedioxymethamphetamine (MDMA) disrupts function of the endocrine system and differentorgans such as heart, blood vessels, kidney, liver and nervous systems.
Nadia Hossein-Zadeh +4 more
doaj +1 more source