Results 201 to 210 of about 15,040 (247)

(±)-MDMA and its enantiomers: potential therapeutic advantages of R(−)-MDMA

Psychopharmacology, 2017
The use of (±)-3,4-methylenedioxymethamphetamine ((±)-MDMA) as an adjunct to psychotherapy in the treatment of psychiatric and behavioral disorders dates back over 50 years. Only in recent years have controlled and peer-reviewed preclinical and clinical studies lent support to (±)-MDMA's hypothesized clinical utility. However, the clinical utility of (±
Elizabeth G, Pitts, Daniel W, Curry, Karly N, Hampshire, Matthew B, Young, Leonard L, Howell   +4 more
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Ecstasy (MDMA) dependence

Drug and Alcohol Dependence, 1999
Methylenedioxymethamphetamine (MDMA) is generally described as non-addictive. However, this report describes three cases in which criteria for dependence were met. A wider understanding that MDMA can be addictive in rare cases is important as very heavy use may cause lasting neuronal changes. This risk could be reduced with effective identification and
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Methylenedioxymethamphetamine (MDMA, “Ecstasy”)

Pediatric Emergency Care, 2000
Ecstasy (MDMA) is an amphetamine derivative of growing popularity. The drug produces a range of toxicities when taken either in standard doses or overdose. In overdose it has major toxicity, producing several different life-threatening manifestations. Hepatotoxicity and hyponatremia are common but poorly understood consequences of MDMA overdose.
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MDMA and the “Ecstasy Paradigm”

Journal of Psychoactive Drugs, 2014
For nearly 30 years, there has been a steady flow of research papers highlighting the dangers of MDMA and the implications for ecstasy users. After such a long time, it would be reasonable to expect that these dangers would be obvious due to the large number of ecstasy users.
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Discriminative profile of MDMA

Pharmacology Biochemistry and Behavior, 1986
Groups of rats were trained to discriminate the stimulus properties of dopaminergically and/or serotonergically active drugs, viz., apomorphine, fenfluramine, tetrahydro-beta-carboline (THBC) and l-cathinone. Once trained, these animals were given several doses of drugs used in training and dose-response relationships and ED50 values were generated ...
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A Clinical Crossroads for MDMA

Journal of Psychoactive Drugs, 2005
Clinical studies of MDMA have been hindered by the fear of harming participants through MDMA-induced neurotoxicity. However, experimental animal studies and brain imaging studies of recreational Ecstasy users have not evidenced that a therapeutic dose of MDMA would be sufficient to cause long-term serotonergic deficits.
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The Background and Chemistry of MDMA

Journal of Psychoactive Drugs, 1986
(1986). The Background and Chemistry of MDMA. Journal of Psychoactive Drugs: Vol. 18, MDMA: Proceedings of the Conference, pp. 291-304.
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The effects of MDMA preexposure on MDMA-induced taste aversions

2023
Although changes in a drug's aversive effects may impact its abuse potential, little is known about factors that impact the aversive effects of MDMA. To that end, the present study used the conditioned taste aversion (CTA) preparation to assess how prior MDMA experience may affect the drug's aversive properties.
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MDMA and the Military

2023
Abstract In the 1920s, physicians discovered the potential for ‘speech induction’ offered by psychoactive substances. The German Nazis were the first to conduct experiments on the use of ‘truth drugs’ for interrogation purposes. Later, after some American prisoners of war ‘confessed’ to the use of biological weapons in the Korean war ...
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MDMA

2008
Sandra Mcpherson, Errol Yudko
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