Results 61 to 70 of about 33,091 (208)

MDMA-Induced Dissociative State not Mediated by the 5-HT2A Receptor

Frontiers in Pharmacology, 2017
Previous research has shown that a single dose of MDMA induce a dissociative state, by elevating feelings of depersonalization and derealization. Typically, it is assumed that action on the 5-HT2A receptor is the mechanism underlying these psychedelic ...
Drew J. Puxty, Johannes G. Ramaekers, Rafael de la Torre, Rafael de la Torre, Rafael de la Torre, Magí Farré, Magí Farré, Magí Farré, Neus Pizarro, Neus Pizarro, Mitona Pujadas, Mitona Pujadas, Kim P. C. Kuypers   +12 more
doaj   +1 more source

Effects of 3,4-methylenedioxymethamphetamine administration on retinal physiology in the rat.

PLoS ONE, 2011
3,4-Methylenedioxymethamphetamine (MDMA; ecstasy) is known to produce euphoric states, but may also cause adverse consequences in humans, such as hyperthermia and neurocognitive deficits. Although MDMA consumption has been associated with visual problems,
João Martins, Miguel Castelo-Branco, Ana Batista, Bárbara Oliveiros, Ana Raquel Santiago, Joana Galvão, Eduarda Fernandes, Félix Carvalho, Cláudia Cavadas, António F Ambrósio   +9 more
doaj   +1 more source

Paraklooramfetamiini mõju psühhomotoorsele aktiivsusele ja serotoniini ja dopamiini tasemetele septumis ja prefrontaalkorteksis erineva püsisotsiaalsusega loomadel [PDF]

, 2018
Social behaviour plays important role in many psychopathologies. Sociability has been shown to be a stable trait in animals and individual differences in sociability are related to 5-HT transmission in septum and prefrontal cortex. The aim of the current
Kastein, Gisela
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MDMA Decreases Gluatamic Acid Decarboxylase (GAD) 67-Immunoreactive Neurons in the Hippocampus and Increases Seizure Susceptibility: Role for Glutamate [PDF]

, 2016
3,4-Methylenedioxy-methamphetamine (MDMA) is a unique psychostimulant that continues to be a popular drug of abuse. It has been well documented that MDMA reduces markers of 5-HT axon terminals in rodents, as well as humans.
Gudelsky, Gary A., Herman, James P., Huff, Courtney L., Morano, Rachel L., Yamamoto, Bryan K.   +4 more
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Prospective memory functioning among ecstasy/polydrug users: evidence from the Cambridge Prospective Memory Test (CAMPROMPT) [PDF]

, 2011
Rationale: Prospective memory (PM) deficits in recreational drug users have been documented in recent years. However, the assessment of PM has largely been restricted to self-reported measures that fail to capture the distinction between event-based and
A Costa, A Miyake, A Rey, BA Wilson, BA Wilson, BG Tabachnick, C Montgomery, C Montgomery, C Montgomery, C Thompson, Catharine Montgomery, CC Adda, D Tomasi, DM Spooner, F Hadjiefthyvoulou, Florentia Hadjiefthyvoulou, HC Fox, HG Pope Jr, J Fleming, J Okuda, J Raven, J Rodgers, J Rodgers, JD Henry, JE Fisk, JE Fisk, John E. Fisk, JR Crawford, JR Leitz, KL Medina, L Reneman, L Reneman, M Kliegel, MA McDaniel, N Solowij, Nikola Bridges, PG Rendell, PG Rendell, PG Rendell, PN Murphy, PW Burgess, R Hannon, RA Dixon, RL Marsh, RM Roth, S McHale, SJ Gilbert, T Martin, T Paraskevaides, TM Heffernan, TM Heffernan, Y Goto, YCT Groot   +52 more
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Effect of the CB1 cannabinoid agonist WIN 55212-2 on the acquisition and reinstatement of MDMA-induced conditioned place preference in mice

Behavioral and Brain Functions, 2010
Background Numerous reports indicate that MDMA users consume other psychoactive drugs, among which cannabis is one of the most common. The aim of the present study was to evaluate, using the conditioned place preference, the effect of the cannabinoid ...
Miñarro José, Aguilar María A, Maldonado Concepción, Daza-Losada Manuel, Rodríguez-Arias Marta, Manzanedo Carmen   +5 more
doaj   +1 more source

The ameliorating effects of Vitamin E on hepatotoxicity of ecstasy

Journal of Research in Medical Sciences, 2020
Background: The production of stress oxidative condition in body which is caused by consumption of ecstasy (3,4-methylenedioxymethamphetamine [MDMA]) leads to a liver damage.
Masoumeh Zirak Javanmard, Khadije Meghrazi, Sayed Soran Ghafori, Mojtaba Karimipour   +3 more
doaj   +1 more source

Substance use in the club scene of Rome : a pilot study [PDF]

, 2014
Date of Acceptance: 28/08/2014 Copyright © 2014 Alessandro Emiliano Vento et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium ...
Acciavatti, Tiziano, Bonifaci, Ludovica, Carrus, Dario, Chillemi, Eleonora, Cinosi, Eduardo, Corazza, Ornella, di Giannantonio, Massimo, Lupi, Matteo, Martinotti, Giovanni, Santacroce, Rita, Schifano, Fabrizio, Vento, Alessandro   +11 more
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MDMA-facilitated cognitive-behavioural conjoint therapy for posttraumatic stress disorder: an uncontrolled trial

European Journal of Psychotraumatology, 2020
Cognitive-behavioural conjoint therapy (CBCT) for PTSD has been shown to improve PTSD, relationship adjustment, and the health and well-being of partners. MDMA (3,4-methylenedioxymethamphetamine) has been used to facilitate an individual therapy for PTSD.
Candice M. Monson, Anne C. Wagner, Ann T. Mithoefer, Rachel E. Liebman, Allison A. Feduccia, Lisa Jerome, Berra Yazar-Klosinski, Amy Emerson, Rick Doblin, Michael C. Mithoefer   +9 more
doaj   +1 more source

Market Analysis of Synthetic Drugs: Amphetamine-type Stimulants, New Psychoactive Substances [PDF]

, 2017
An estimated quarter of a billion people, or around 5 per cent of the global adult population, used drugs at least once in 2015. Even more worrisome is the fact that about 29.5 million of those drug users, or 0.6 per cent of the global adult population ...

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