Results 21 to 30 of about 22,933 (184)

Self-reported risks for multiple-drug resistance among new tuberculosis cases: implications for drug susceptibility screening and treatment. [PDF]

open access: yesPLoS ONE, 2011
BACKGROUND: Multiple drug-resistance in new tuberculosis (TB) cases accounts for the majority of all multiple drug-resistant TB (MDR-TB) worldwide. Effective control requires determining which new TB patients should be tested for MDR disease, yet the ...
Timothy F Brewer   +8 more
doaj   +1 more source

Rifampicin resistance in new bacteriologically confirmed pulmonary tuberculosis patients in Cameroon: a cross-sectional survey

open access: yesBMC Research Notes, 2018
Objective In Cameroon, tuberculosis (TB) cases are diagnosed and treated within a nationwide network of 248 diagnostic and treatment centres. In 2016, the centers notified a total of 175 multidrug-resistant (MDR-)TB cases, most of them retreatment cases.
J. Noeske   +4 more
doaj   +1 more source

MDR-TB treatment as prevention: The projected population-level impact of expanded treatment for multidrug-resistant tuberculosis. [PDF]

open access: yesPLoS ONE, 2017
BACKGROUND:In 2013, approximately 480,000 people developed active multidrug-resistant tuberculosis (MDR-TB), while only 97,000 started MDR-TB treatment.
Emily A Kendall   +3 more
doaj   +1 more source

82125 Multiple epidemics of multidrug-resistant tuberculosis revealed by spatial disease mapping and whole-genome sequencing analysis in urban China

open access: yesJournal of Clinical and Translational Science, 2021
IMPACT: Our study will integrate state-of-the-art methods in pathogen genomics, epidemiology, and geospatial analysis to identify both host- and pathogen-factors driving the MDR-TB transmission and the study outcome can inform the design of targeted ...
Chongguang Yang   +6 more
doaj   +1 more source

Rising challenge of multidrug-resistant tuberculosis in China: a predictive study using Markov modeling

open access: yesInfectious Diseases of Poverty, 2020
Background Multidrug-resistant tuberculosis (MDR-TB) is on the rise in China. This study used a dynamic Markov model to predict the longitudinal trends of MDR-TB in China by 2050 and to assess the effects of alternative control measures.
Bing-Ying Li   +8 more
doaj   +1 more source

Towards tailored regimens in the treatment of drug-resistant tuberculosis: a retrospective study in two Italian reference Centres

open access: yesBMC Infectious Diseases, 2019
Background The increased incidence of drug-resistant TB is a major challenge for effective TB control. Limited therapeutic options and poor treatment outcomes of DR-TB may increase drug-resistance rates.
Niccolò Riccardi   +13 more
doaj   +1 more source

Treatment quality and outcome for multidrug-resistant tuberculosis patients in four regions of China: a cohort study

open access: yesInfectious Diseases of Poverty, 2020
Background China incurs an extremely low treatment coverage of multidrug-resistant tuberculosis (MDR-TB). This study aimed to understand the experience of MDR-TB patients on quality of health care, and the clinical impact through an up to six-year follow-
Xu-Bin Zheng   +7 more
doaj   +1 more source

Multidrug-resistant Tuberculosis Burden among the New Tuberculosis Patients in Zhejiang Province: An Observational Study, 2009–2013

open access: yesChinese Medical Journal, 2017
Background: Screening on multidrug-resistant tuberculosis (MDR-TB) has been limited to the serious TB subpopulations excluding the new TB patients. This study aimed to examine MDR-TB burden among the new TB patients.
Ying Peng   +11 more
doaj   +1 more source

Screening and identification of differentially expressed long non-coding RNAs in multidrug-resistant tuberculosis [PDF]

open access: yesPeerJ, 2022
Background Efforts to eradicate tuberculosis are largely threatened by drug-resistant tuberculosis, particularly, multidrug-resistant tuberculosis (MDR-TB).
Junwei Zhao   +6 more
doaj   +2 more sources

Cost-effectiveness of bedaquiline in MDR and XDR tuberculosis in Italy

open access: yesJournal of Market Access & Health Policy, 2017
Objective: To evaluate the cost-effectiveness of bedaquiline plus background drug regimens (BR) for multidrug-resistant tuberculosis (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB) in Italy.
Luigi R. Codecasa   +9 more
doaj   +1 more source

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