Results 41 to 50 of about 252,964 (178)

Decisions in TB diagnosis among high-risk MDR-TB participants.

, 2022
Decisions in TB diagnosis among high-risk MDR-TB participants.
Udomsak Silachamroon (6166172), Nathakorn Pongpeeradech (13162697), Yuthichai Kasetchareo (13162700), Charoen Chuchottaworn (804322), Jaranit Kaewkungwal (190918), Saranath Lawpoolsri (305283)   +5 more
core   +1 more source

The Natural Product Corramycin Acts as a DNA Gyrase Poison and Overcomes Fluoroquinolone Resistance in Mycobacterium tuberculosis

Advanced Science, EarlyView.
Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries, Jennifer Herrmann, Michael Dal Molin, Yaëlle Wormser, Timo Risch, Yunsheng Gao, Gareth Prosser, Francesca Gubellini, Ariel Mechaly, Joshua B. Wallach, Anthony Castro, Arka Banerjee, Sari Rasheed, Alexander Horn, Mathias Müsken, Michael Kurz, Lindsay Sonnenkalb, Viola Dreyer, Stefan Niemann, Sönke Andres, Dirk Schnappinger, Uli Kazmaier, Norbert Reiling, Rolf Müller, Jan Rybniker, Stéphanie Petrella   +25 more
wiley   +1 more source

PERBEDAAN KADAR TSH PADA PENDERITA TB PARU MDR SEBELUM dan SESUDAH MENDAPAT ETIONAMID DI POLI TB MDR RSUD Dr. SOETOMO SURABAYA [PDF]

, 2017
Latar belakang: Kasus Multidrug Resistance Tuberculosis (TB MDR) jumlahnya yang semakin meningkat tiap tahunnya, dimana obat-obatan yang dipakai dalam terapi TB MDR khususnya para-aminosalisilat (PAS) atau etionamid (Etio) atau kombinasi keduanya ...
Latar belakang: Kasus Multidrug Resistance Tuberculosis (TB MDR)
core   +1 more source

One‐Step Immobilized Phage Depolymerase Coatings for Catheter‐Related Bloodstream Infections

Advanced Science, EarlyView.
Catheter‐related bloodstream infections (CRBSI) caused by drug‐resistant Gram‐negative bacteria remain a major clinical challenge. Here, a polydopamine‐assisted depolymerase coating degrades bacterial capsules and restores serum‐mediated killing, effectively suppressing biofilms and reducing bacterial burden in vitro, ex vivo, and in vivo, presenting a
Lingkai Dong, Xingjin Li, Tao Hu, Qianqian Lu, Xiaoxu Zhang, Xi Chen, Yifan Luo, Zhong Zuo, Ronald Man Yeung Wong, Miao Xu, Tiancong Zhao, Sharon Shui Yee Leung   +11 more
wiley   +1 more source

Clinico-radiological Difference Section between Primary and Secondary MDR Pulmonary Tuberculosis [PDF]

Journal of Clinical and Diagnostic Research, 2019
Introduction: Multidrug Resistant Tuberculosis (MDR-TB) is classified into primary and secondary type depending upon history of Anti-TB drug received in past. MDR-TB generally remains undetected in newly detected TB cases as the index of suspicion is low.
Deependra Kumar Rai, Alok
doaj   +1 more source

CTSs’ knowledge about MDR-TB.

, 2022
CTSs’ knowledge about MDR-TB.
J. Christo Heunis (13046945), N. Gladys Kigozi (13046948), Ernest Peresu (13046942), Diana De Graeve (11642908)   +3 more
core   +1 more source

Molecular Glue Degraders Enhance CAPRIN1‐Dependent Lysosomal Degradation of APP and Reduce Amyloid β in Alzheimer's Disease

Advanced Science, EarlyView.
A new class of lysosome‐directed molecular glue degraders selectively enhance CAPRIN1–APP interactions, driving APP degradation and reducing amyloid‐β production in human neurons and Alzheimer's disease mouse models. This CAPRIN1‐dependent targeted protein degradation strategy reveals a previously unrecognized therapeutic approach for disrupting the ...
Sunghan Jung, Xu Wang, Bin Liu, Raktim Roy, Nancy Jaiswal, Ratan K. Rai, Yuichiro Takagi, Cen Gao, Lifan Zeng, Ho‐Yin Lo, Reagan K. Wohlford, Ryan K. Higgins, Bruce T. Lamb, Anantha Shekhar, Anita C. Bellail, Chunhai Hao   +15 more
wiley   +1 more source

Operational challenges in diagnosing multi-drug resistant TB and initiating treatment in Andhra Pradesh, India. [PDF]

PLoS ONE, 2011
BACKGROUND: Revised National TB Control Programme (RNTCP), Andhra Pradesh, India. There is limited information on whether MDR-TB suspects are identified, undergo diagnostic assessment and are initiated on treatment according to the programme guidelines ...
Sarabjit S Chadha, B N Sharath, Kishore Reddy, Jyothi Jaju, P H Vishnu, Sreenivas Rao, Malik Parmar, Srinath Satyanarayana, Kuldeep Singh Sachdeva, Nevin Wilson, Anthony D Harries   +10 more
doaj   +1 more source

Critical Roles of O‐Acetylation Revealed by Synthetic Trisaccharide Antigens for a Broad‐Spectrum Anti‐Salmonella Vaccine

Advanced Science, EarlyView.
A synthetic glycoconjugate vaccine based on a diacetylated Salmonella trisaccharide elicits broadly protective antibodies against four major human pathogenic serovars. Mechanistic studies identify 2,3‐di‐O‐acetylation of rhamnose as a critical determinant of antigen recognition and breadth of protection, establishing a new strategy for broad‐spectrum ...
Xingling Pan, Soham Maity, Herbert Kavunja, Yuvarani Murali, Ting‐An Chen, Chang‐xin Huo, Scott M. Baliban, Xuefei Huang   +7 more
wiley   +1 more source

Multidrug-Resistant Tuberculosis 
Outbreak among US-bound Hmong 
Refugees, Thailand, 2005

Emerging Infectious Diseases, 2008
In January 2005, tuberculosis (TB), including multidrug-resistant TB (MDR TB), was reported among Hmong refugees who were living in or had recently immigrated to the United States from a camp in Thailand.
John E. Oeltmann, Jay K. Varma, Luis Ortega, Yecai Liu, Thomas O’Rourke, Maria Cano, Theresa A. Harrington, Sean Toney, Warren Jones, Samart Karuchit, Lois Diem, Dhanida Rienthong, Jordan W. Tappero, Kashef Ijaz, Susan A. Maloney   +14 more
doaj   +1 more source