Results 41 to 50 of about 260,112 (235)

PERBEDAAN KADAR TSH PADA PENDERITA TB PARU MDR SEBELUM dan SESUDAH MENDAPAT ETIONAMID DI POLI TB MDR RSUD Dr. SOETOMO SURABAYA [PDF]

, 2017
Latar belakang: Kasus Multidrug Resistance Tuberculosis (TB MDR) jumlahnya yang semakin meningkat tiap tahunnya, dimana obat-obatan yang dipakai dalam terapi TB MDR khususnya para-aminosalisilat (PAS) atau etionamid (Etio) atau kombinasi keduanya ...
Latar belakang: Kasus Multidrug Resistance Tuberculosis (TB MDR)
core   +1 more source

Chimeric IL‐6/4R‐LL37 Engineered Macrophages Achieve Synchronized Inflammation Control and Antimicrobial Defence in Sepsis

Advanced Science, EarlyView.
Engineered macrophages programmed in situ by LNP‐delivered IL‐6/4 fusion and LL37 mRNAs simultaneously dampen cytokine storm, promote M2‐like repair, and enhance direct bacterial killing in sepsis. This combinatorial strategy restores T cell and macrophage function, lowers organ bacterial burden, and improves survival, highlighting a precision, host ...
Tianyang Jie, Zheyu Zhang, Hao Zhang, Linke Bian, Penglong Zheng, Sijia Zhou, Minqi Wang, Mingyu Qu, Yufei Wang, Xinhua Qu, Bing Yue   +10 more
wiley   +1 more source

MDR-TB data

, 2019
This is the dataset for my MDR-TB ...
zhijie zhang (7141082)
core   +1 more source

Clinico-radiological Difference Section between Primary and Secondary MDR Pulmonary Tuberculosis [PDF]

Journal of Clinical and Diagnostic Research, 2019
Introduction: Multidrug Resistant Tuberculosis (MDR-TB) is classified into primary and secondary type depending upon history of Anti-TB drug received in past. MDR-TB generally remains undetected in newly detected TB cases as the index of suspicion is low.
Deependra Kumar Rai, Alok
doaj   +1 more source

One‐Step Immobilized Phage Depolymerase Coatings for Catheter‐Related Bloodstream Infections

Advanced Science, EarlyView.
Catheter‐related bloodstream infections (CRBSI) caused by drug‐resistant Gram‐negative bacteria remain a major clinical challenge. Here, a polydopamine‐assisted depolymerase coating degrades bacterial capsules and restores serum‐mediated killing, effectively suppressing biofilms and reducing bacterial burden in vitro, ex vivo, and in vivo, presenting a
Lingkai Dong, Xingjin Li, Tao Hu, Qianqian Lu, Xiaoxu Zhang, Xi Chen, Yifan Luo, Zhong Zuo, Ronald Man Yeung Wong, Miao Xu, Tiancong Zhao, Sharon Shui Yee Leung   +11 more
wiley   +1 more source

Multiple Introductions of Multidrug-Resistant Tuberculosis into Households, Lima, Peru

Emerging Infectious Diseases, 2011
Two cases of multidrug-resistant tuberculosis (MDR TB) in a household are assumed to reflect within-household transmission. However, in high-incidence areas of MDR TB, secondary cases may arise through exposure to MDR TB in the community. To estimate the
Ted Cohen, Megan B. Murray, Ibrahim Abubakar, Zibiao Zhang, Alexander Sloutsky, Fernando Arteaga, Katiuska Chalco, Molly F. Franke, Mercedes C. Becerra   +8 more
doaj   +1 more source

Molecular Glue Degraders Enhance CAPRIN1‐Dependent Lysosomal Degradation of APP and Reduce Amyloid β in Alzheimer's Disease

Advanced Science, EarlyView.
A new class of lysosome‐directed molecular glue degraders selectively enhance CAPRIN1–APP interactions, driving APP degradation and reducing amyloid‐β production in human neurons and Alzheimer's disease mouse models. This CAPRIN1‐dependent targeted protein degradation strategy reveals a previously unrecognized therapeutic approach for disrupting the ...
Sunghan Jung, Xu Wang, Bin Liu, Raktim Roy, Nancy Jaiswal, Ratan K. Rai, Yuichiro Takagi, Cen Gao, Lifan Zeng, Ho‐Yin Lo, Reagan K. Wohlford, Ryan K. Higgins, Bruce T. Lamb, Anantha Shekhar, Anita C. Bellail, Chunhai Hao   +15 more
wiley   +1 more source

Transmission of multidrug-resistant tuberculosis in the UK: a cross-sectional molecular and epidemiological study of clustering and contact tracing [PDF]

, 2014
BACKGROUND: Between 2000 and 2012 the number of multidrug-resistant (MDR) tuberculosis cases in the UK increased from 28 per year to 81 per year. We investigated the proportion of MDR tuberculosis cases arising from transmission in the UK and associated ...
Abubakar, Ibrahim, Anderson, Laura F, Brown, Timothy, Watson, JP, Abubakar, I, Tamne, Surinder, Mullarkey, C, Anderson, LF, Tamne, S, Zenner, D, Brown, T, Mullarkey, Catherine, Watson, John P, Zenner, Dominik   +13 more
core   +1 more source

Operational challenges in diagnosing multi-drug resistant TB and initiating treatment in Andhra Pradesh, India. [PDF]

PLoS ONE, 2011
BACKGROUND: Revised National TB Control Programme (RNTCP), Andhra Pradesh, India. There is limited information on whether MDR-TB suspects are identified, undergo diagnostic assessment and are initiated on treatment according to the programme guidelines ...
Sarabjit S Chadha, B N Sharath, Kishore Reddy, Jyothi Jaju, P H Vishnu, Sreenivas Rao, Malik Parmar, Srinath Satyanarayana, Kuldeep Singh Sachdeva, Nevin Wilson, Anthony D Harries   +10 more
doaj   +1 more source

Critical Roles of O‐Acetylation Revealed by Synthetic Trisaccharide Antigens for a Broad‐Spectrum Anti‐Salmonella Vaccine

Advanced Science, EarlyView.
A synthetic glycoconjugate vaccine based on a diacetylated Salmonella trisaccharide elicits broadly protective antibodies against four major human pathogenic serovars. Mechanistic studies identify 2,3‐di‐O‐acetylation of rhamnose as a critical determinant of antigen recognition and breadth of protection, establishing a new strategy for broad‐spectrum ...
Xingling Pan, Soham Maity, Herbert Kavunja, Yuvarani Murali, Ting‐An Chen, Chang‐xin Huo, Scott M. Baliban, Xuefei Huang   +7 more
wiley   +1 more source