Results 11 to 20 of about 242,558 (273)

Restoring endoplasmic reticulum homeostasis improves functional recovery after spinal cord injury

Neurobiology of Disease, 2013
The endoplasmic reticulum (ER) stress response (ERSR) is activated to maintain protein homeostasis or induce apoptosis in the ER in response to distinct cellular insults including hypoxia, inflammation, and oxidative damage.
Sujata Saraswat Ohri, Michal Hetman, Scott R. Whittemore   +2 more
doaj   +1 more source

Rifampicin resistance in new bacteriologically confirmed pulmonary tuberculosis patients in Cameroon: a cross-sectional survey

BMC Research Notes, 2018
Objective In Cameroon, tuberculosis (TB) cases are diagnosed and treated within a nationwide network of 248 diagnostic and treatment centres. In 2016, the centers notified a total of 175 multidrug-resistant (MDR-)TB cases, most of them retreatment cases.
J. Noeske, A. Nana Yakam, J. L. Abena Foe, D. Nguafack, C. Kuaban   +4 more
doaj   +1 more source

Stenotrophomonas maltophilia – Clinical Significance, Treatment of Infections

Postępy Mikrobiologii, 2023
Stenotrophomonas maltophilia to istotny czynnik etiologiczny zakażeń u pacjentów z zaburzonym funkcjonowaniem układu immunologicznego, poddanych inwazyjnym zabiegom diagnostycznym i terapeutycznym, z chorobą nowotworową czy mukowiscydozą.
Nowicka Joanna, Janczura Adriana, Lelonkiewicz Martyna   +2 more
doaj   +1 more source

Following spinal cord injury, PDE4B drives an acute, local inflammatory response and a chronic, systemic response exacerbated by gut dysbiosis and endotoxemia

Neurobiology of Disease, 2019
Emerging evidence links changes in the gut microbiome and intestinal barrier function to alterations in CNS function. We examined the role of endotoxin-responsive, cAMP-specific, Pde4 subfamily b (Pde4b) enzyme in gut dysbiosis induced neuro-inflammation
Scott A. Myers, Leila Gobejishvili, Sujata Saraswat Ohri, C. Garrett Wilson, Kariena R. Andres, Amberly S. Riegler, Hridgandh Donde, Swati Joshi-Barve, Shirish Barve, Scott R. Whittemore   +9 more
doaj   +1 more source

High presacral collection approached through the perineal route: A novel computed tomography-guided technique

South African Journal of Radiology, 2021
For a definitive diagnosis of abdomino-pelvic lesions, percutaneous aspiration or biopsy is often necessary; however, finding a safe ‘window’ for access is challenging.
Shuchi Bhatt, Harsit Bansal, Sagar Nayak, Saumya Dangwal   +3 more
doaj   +1 more source

Genomic insights into the rapid emergence and evolution of MDR in Staphylococcus pseudintermedius. [PDF]

, 2014
OBJECTIVES: MDR methicillin-resistant Staphylococcus pseudintermedius (MRSP) strains have emerged rapidly as major canine pathogens and present serious treatment issues and concerns to public health due to their, albeit low, zoonotic potential. A further
A. J. McCarthy, A. Loeffler, A. Waller, B. Leggett, Bannoehr, Besier, Black, Bond, Croucher, D. H. Lloyd, Darling, De Lucia, E. M. Harrison, Feil, Feng, Geoghegan, Gortel, J. A. Lindsay, K. Stanczak-Mrozek, Kadlec, Koser, Loeffler, Loeffler, M. A. Holmes, Magiorakos, Noguchi, Prescott, Quail, Roberts, Ruscher, Rutherford, Soedarmanto   +31 more
core   +3 more sources

Redox control of multidrug resistance and Its possible modulation by antioxidants [PDF]

, 2016
Clinical efficacy of anticancer chemotherapies is dramatically hampered by multidrug resistance (MDR) dependent on inherited traits, acquired defence against toxins, and adaptive mechanisms mounting in tumours.
Cort, A., De Luca, C., Korkina, L., Ozben, T., Saso, Luciano   +4 more
core   +3 more sources

Household screening and multidrug-resistant tuberculosis [PDF]

, 2010
Of the estimated half a million people who develop multidrug resistant (MDR) tuberculosis each year, less than 7% are diagnosed and only 1 in 5 of these have access to eff ective treatment.1 To control this epidemic, dramatically increased efforts are ...
Becerra, Gilles van Cutsem, Helen Cox, Keshavjee, Lin, London, Mitnick, Mitnick, Morán-Mendoza, Rieder   +9 more
core   +2 more sources

Epidemiology of Neonatal Septicemia in the Era of Extended Spectrum Beta-Lactamase Producing Bacteria: A Prospective Study in a Tertiary Referral Hospital

Journal of Pure and Applied Microbiology, 2020
A surge of extended spectrum beta lactamase (ESBL)-producers is being witnessed in the neonatal intensive care units (NICUs). Hence, the present study was conducted to analyze both the bacteriological profile and clinical outcome of neonatal septicemia ...
Dina M. Hassan, Lamiaa A. Madkour, Walaa A. Abuelhamd   +2 more
doaj   +1 more source

Treatment outcomes for children with multidrug-resistant tuberculosis: a systematic review and meta-analysis [PDF]

, 2012
BACKGROUND: Paediatric multidrug-resistant (MDR) tuberculosis is a public health challenge of growing concern, accounting for an estimated 15% of all global cases of MDR tuberculosis. Clinical management is especially challenging, and recommendations are
Abubakar, Al-Dabbagh, Borenstien, Caminero, Dena Ettehad, Drobac, du Cros, Fairlie, Falzon, Feja, Furin, Furin, Golder, Graham S Cooke, Granich, Guyatt, H Simon Schaaf, Hesseling, Hesseling, Houwert, James A Seddon, Johnston, Laserson, Leung, Mendez Echevarria, Mitnick, Munsiff, Nathan Ford, Nelson, Newcombe, Nicol, Orenstein, Padayatchi, Riley, Rucker, Schaaf, Schaaf, Schaaf, Schaaf, Schaaf, Seddon, Smith, Swanson   +42 more
core   +2 more sources