Results 31 to 40 of about 154,201 (275)

The nuclear membrane in multidrug resistance: microinjection of epirubicin into bladder cancer cell lines

open access: yes, 2005
Objevtive: to assess whether microinjecting epirubicin into cells showing multidrug resistance (MDR, common to many cancers, including bladder cancer, with resistance to, e.g.
Birch, B.R   +5 more
core   +1 more source

Virulence Characteristics, Antibiotic Resistance Patterns and Molecular Typing of Enteropathogenic Producing Escherichia coli (EPEC) Isolates in Eastern Province of Saudi Arabia: 2013–2014

open access: yesInfection and Drug Resistance, 2022
Lamya Zohair Yamani, Nasreldin Elhadi Department of Clinical Laboratory Science, College of Applied Medical Sciences, Imam Abdulrahman Bin Faisal University, Dammam, Kingdom of Saudi ArabiaCorrespondence: Nasreldin Elhadi, Department of Clinical ...
Yamani LZ, Elhadi N
doaj  

Chemoproteomic Identification of AKT2 as a Paclitaxel‐Binding Protein via C─C Bond‐Linked Probe PTX‐4 in Paclitaxel‐Resistant Breast Cancer

open access: yesAdvanced Science, EarlyView.
ABSTRACT Breast cancer remains one of the most prevalent malignancies among women, and taxane‐based chemotherapies such as paclitaxel and docetaxel are central to standard treatment regimens. However, drug resistance in breast cancer limits therapeutic efficacy and contributes to recurrence and metastasis.
Kai Wang   +7 more
wiley   +1 more source

Progress of Research on ABC Transporters in Tumor Multidrug Resistance

open access: yesZhongliu Fangzhi Yanjiu
The ATP-binding cassette (ABC) transporter superfamily comprises membrane proteins that efflux various substrates across extra- and intracellular membranes. Among them, ABCB1, ABCG2, and ABCC1 are directly linked to tumor multidrug resistance (MDR). This
Xiaoke XING   +4 more
doaj   +1 more source

Plants in our combating strategies against Mycobacterium tuberculosis: progress made and obstacles met

open access: yesPharmaceutical Biology, 2017
Context: Traditionally used plants for treating chest-related problems/tuberculosis (TB) have not been evaluated in detail and hence a thorough study is needed in this regard. This knowledge may find application in developing new anti-TB drugs. Objective:
Vivek Kumar Gupta   +3 more
doaj   +1 more source

Detection of pelA and associated virulence genes in emerging multidrug- and extensively drug-resistant (MDR and XDR) Pseudomonas aeruginosa isolated from Oreochromis niloticus

open access: yesBulgarian Journal of Veterinary Medicine, 2023
Pseudomonas aeruginosa is one of the common pathogens causing serious infections in fish, conse-quently high economic losses in freshwater aquaculture. This study was carried out to investigate the prevalence, antibiotic sensitivity, and distribution of ...
R. M. El-Tarabili   +3 more
doaj   +1 more source

Polychip‐A High‐Throughput Droplet Microfluidics Platform for Interrogating Microbial Interactions

open access: yesAdvanced Science, EarlyView.
Polychip, a fully integrated droplet microfluidics platform, enables high‐throughput, single‐cell resolution screening of polymicrobial interactions. By seamlessly combining six automated microfluidics operations on a single chip, the system accelerates antimicrobial discovery by 11 to 14 times compared to traditional robotic methods.
Jeong Jae Han   +11 more
wiley   +1 more source

Characterization of enterotoxin, antibiotic resistance genes, and antimicrobial susceptibility profiling of Staphylococcus aureus isolated from table eggs: Implications for food safety and public health

open access: yesOpen Veterinary Journal
Background: Staphylococcus aureus is a significant pathogen in both clinical and food safety contexts, capable of contaminating table eggs, which are a common dietary staple worldwide.
Palash Bose   +8 more
doaj   +1 more source

Dual‐Functional Silent‐Region SERS Nanoplatform for Real‐Time Bacterial Tracking and Wound Healing Therapy

open access: yesAdvanced Science, EarlyView.
ABSTRACT Bacterial wound infections, particularly those caused by Escherichia coli and Pseudomonas aeruginosa, are difficult to treat due to biofilm formation, multidrug resistance, and chronic inflammation. Here, we report a multifunctional nanoplatform based on a surface‐enhanced Raman scattering (SERS) probe that enables simultaneous photodynamic ...
Hanbin Deng   +6 more
wiley   +1 more source

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