Results 51 to 60 of about 141,033 (287)

Molecular detection of blaSHV gene in multidrug resistance of Klebsiella pneumoniae isolated from chicken egg shell swab from a traditional market in Surabaya

Open Veterinary Journal
Background: Contamination with Klebsiella pneumoniae in food ingredients, including eggs, causes various dangers because it threatens public health, because it acts as a multidrug resistance (MDR) bacteria, especially the extendedspectrum beta-lactamase
Azhari Athaillah Sulaiman, Mustofa Helmi Effendi, Leonardo Reza Srimaryanto, Aswin Rafif Khairullah, Pitaloka Kurniasari, Wiwiek Tyasningsih, Ikechukwu Benjamin Moses, Riza Zainuddin Ahmad, Saifur Rehman, Budiastuti Budiastuti, Daniah Ashri Afnani, Sheila Marty Yanestria, Katty Hendriana Priscilia Riwu, Agus Widodo   +13 more
doaj   +1 more source

Non-clinical isolates as potential reservoirs of antibiotic resistance in Port Harcourt, Nigeria

The Pan African Medical Journal, 2018
INTRODUCTION: Multidrug resistance (MDR) is a growing problem worldwide. This type resistance often arises due to the sequential acquisition of drug resistance determinants and subsequent clonal spread.
Kome Otokunefor, Paul Agbude, Tosanwumi Vincent Otokunefor   +2 more
doaj   +1 more source

Inside‐Outside ROS Therapeutic Strategy Based on Piezoelectric Nano‐Urchin for Drug‐Resistant Bacteria Biofilm Infections

Advanced Science, EarlyView.
The contribution of this study lies not only in enabling effective treatment of drug‐resistant biofilm infections, but also in establishing a transferable therapeutic paradigm: Ultrasound‐triggered mechanical forces synergistically enhance piezoelectric polarization and nanozyme activity, driving functional ROS generation inside and outside biofilms ...
Xinjian Guo, Jin Yang, Mengjie An, Bingjie Lin, Tao Liu, Limin Zhang   +5 more
wiley   +1 more source

Short-Course Chemotherapy Regimens for Treatment of Multiple and Pre-Extensive Drug Resistant Tuberculosis in Combination with Surgery in Older Children and Adolescents

Туберкулез и болезни лёгких
The objective: to evaluate the effectiveness of short-curse chemotherapy regimens for treatment of MDR/pre-XDR tuberculosis in combination with surgery in older children and adolescents.Subjects and Methods.
E. S. Ovsyankina, L. V. Panova, E. A. Krushinskaya, M. A. Bagirov   +3 more
doaj   +1 more source

Targeting Lipopolysaccharide Transport Induces Membrane Lipid Remodeling and Sensitizes Acinetobacter baumannii to Colistin Treatment

Advanced Science, EarlyView.
This study identifies C4 as a lead inhibitor of the Lpt system. Notably, C4 potentiates colistin activity by disrupting LPS transport and remodeling phospholipid homeostasis, revealing a functional interplay between the Lpt and Mla systems. These findings establish a mechanistic link between Lpt inhibition and membrane lipid remodeling, positioning Lpt–
Jianya Luo, Hetianzi Zhang, Jinju Cai, Shuang Zhou, Haijie Zhang, Zhiqiang Wang, Yuan Liu   +6 more
wiley   +1 more source

Bacterial Profile of Urinary Tract Infections and Antibiotic Resistance Pattern in a Tertiary Care Hospital

Online Journal of Health & Allied Sciences, 2020
Background: Due to emergence of multidrug resistance, empirical treatment of Urinary tract infections is becoming intricate. Aim: To know the bacteria causing UTI, their antibiogram and possibility of using fosfomycin as an empirical drug.
Mangalgi Smita S, Sanjay S Wavare, Shivali Gajul, Annapurna G Sajjan   +3 more
doaj  

Cetuximab-Modified Human Serum Albumin Nanoparticles Co-Loaded with Doxorubicin and MDR1 siRNA for the Treatment of Drug-Resistant Breast Tumors

International Journal of Nanomedicine, 2021
Xin Yang,1– 3 Yifan Wang,1– 3 Si Chen,1– 3 Shuang Zhang,1– 3 Chunying Cui1– 3 1School of Pharmaceutical Sciences, Capital Medical University, Beijing, 100069, People’s Republic of China; 2Engineering Research Center of Endogenous Prophylactic of Ministry
Yang X, Wang Y, Chen S, Zhang S, Cui C
doaj  

HUBUNGAN DUKUNGAN KELUARGA DENGAN EFIKASI DIRI PENDERITA TUBERCULOSIS MULTIDRUG RESISTANT (TB-MDR) DI POLI TB-MDR RSUD IBNU SINA GRESIK [PDF]

, 2018
TB-MDR terjadi karena kegagalan pengobatan, putus pengobatan, atau pengobatan yang tidak benar sehingga terjadinya resistensi primer. Penelitian ini bertujuan untuk menganalisis hubungan antara dukungan keluarga dengan Efikasi Diri penderita ...
Andri, Setya Wahyudi, Makhfudli, Makhfudli, Mar'atul Hasanah, -   +2 more
core  

Dual‐Functional Silent‐Region SERS Nanoplatform for Real‐Time Bacterial Tracking and Wound Healing Therapy

Advanced Science, EarlyView.
ABSTRACT Bacterial wound infections, particularly those caused by Escherichia coli and Pseudomonas aeruginosa, are difficult to treat due to biofilm formation, multidrug resistance, and chronic inflammation. Here, we report a multifunctional nanoplatform based on a surface‐enhanced Raman scattering (SERS) probe that enables simultaneous photodynamic ...
Hanbin Deng, Rui Wang, Dianqi Zhang, Wei Zhang, Jaebum Choo, Fabiao Yu, Shaowen Cheng   +6 more
wiley   +1 more source

Harmonizing Rigidity and Flexibility: Embedding COF Quantum Dots Into Extracellular Matrix Gel as Carbon Monoxide Depot for Acoustically Triggered Time‐Programmable Anti‐Infective Therapy

Advanced Science, EarlyView.
A rigid‑flexible integrated CO depot is engineered by embedding rigid COFQDs into a flexible ECM gel network. The rigid framework enables high‑capacity CO storage and sonodynamic bacterial killing, while the flexible ECM gel controls sustained CO release, collectively eradicating multidrug‑resistant infection and promoting scarless healing.
Baohong Sun, Fang Han, Chunxiao Zhu, Zhiyuan Yang, Haoru Wang, Jinpei Mei, Jie Chen, Jingwen Zhu, Zihan Bo, Taju Wu, Xiaogang Zhou, Tao Ma, Yutian Su, Youhui Lin   +13 more
wiley   +1 more source