Results 161 to 170 of about 1,218,574 (359)

Pharmacokinetics, pharmacodynamics and safety of vutiglabridin after multiple oral administrations in healthy female and obese subjects

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Vutiglabridin (HSG4112) is a novel drug under clinical development for antiobesity treatment. This study aimed to evaluate the pharmacokinetics (PKs) and safety of vutiglabridin after multiple oral administrations in healthy Korean female and obese subjects and explore short‐term pharmacodynamic (PD) responses.
Sooyoun Lee   +5 more
wiley   +1 more source

Kur’an-ı Kerim Meallerinde Benzer Anlamlılık Sorunu: فعل , صنع veعمل Örneği

open access: yesEskiyeni, 2017
Diller içerisinde bulunan benzer anlamlı sözcükler, çeviri çalışmaları sırasında, üzerinde hassasiyetle durulması gereken konulardan biridir. Çünkü bu tür sözcükler arasındaki anlam nüansları, çeviride büyük anlam kaymalarına ya da detay kayıplarına yol ...
Ayşe Hümeyra Rızvanoğlu
doaj  

Population pharmacokinetics of TBAJ‐587 and its main metabolites—Evaluation of different loading dose strategies and early dose selection

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Background and Aim The rise of drug‐resistant tuberculosis (TB) poses a need for new drugs and combinations. TBAJ‐587, a new diarylquinoline (DARQ), has shown promising efficacy in preclinical studies. This work aimed to describe the pharmacokinetics (PK) of TBAJ‐587 and its metabolites M2 and M3 after single ascending dosing in healthy volunteers and ...
Albin A. M. Leding   +6 more
wiley   +1 more source

An open‐label, single‐arm, dose‐escalating concentration–QT study to investigate the cardiac effects and safety of paroxetine in healthy adults

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Paroxetine is a selective serotonin reuptake inhibitor (SSRI), approved for treatment of major depressive disorder and anxiety disorders. Some SSRIs are known to prolong the QT interval; however, clinical evidence to establish a lack of association between paroxetine and corrected QT interval (QTc) prolongation is limited. Therefore, this
Sven C. van Dijkman   +6 more
wiley   +1 more source

Cannabinoids and drug–drug pharmacokinetic interactions: Deciphering the risks

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
The relationship between cannabinoids and mental health has become a major focus of scientific inquiry and public discourse. Cannabinoids are diverse chemical compounds from the Cannabis species that have been explored for their therapeutic applications in treating chronic pain, psychiatric and neurological conditions, such as depression, schizophrenia,
Paraskevi Papakyriakopoulou   +2 more
wiley   +1 more source

ÇEVİRİ KURAMLARI AÇISINDAN M. HAMDİ YAZIR’IN MEAL YÖNTEMİ

open access: yesCumhuriyet Üniversitesi İlahiyat Fakültesi Dergisi, 2005
M. Hamdi Yazır, Cumhuriyet döneminin en önemli müfessirlerden biridir. Bu durum onun mealini oldukça önemli hale getirmektedir. Makalede Yazır’ın meal tarzı, kaynak veya amaç metni dikkate alan teoriler, çeviri normları ve metin çeşitleri açısından ...
İBRAHİM HİLMİ KARSLI
doaj  

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