Results 191 to 200 of about 1,201,079 (362)

Dietary Nucleotides Improve Growth of Juvenile <i>Eriocheir sinensis</i> Under a Low-Fish Meal Diet via Enhanced Feed Intake and Gut Health. [PDF]

Aquac Nutr
Wang S, Li W, Yan Y, Li E, Wang X, Qin JG, Chen L.   +6 more
europepmc   +1 more source

Absolute bioavailability and intravenous pharmacokinetics of N‐acetyl‐D‐mannosamine in humans

British Journal of Clinical Pharmacology, EarlyView.
Aims N‐acetyl‐D‐mannosamine monohydrate (ManNAc) is a naturally occurring monosaccharide that has attracted considerable attention for its potential in treating GNE myopathy, a rare autosomal recessive muscle disorder. Despite its promise as an oral treatment, the absolute bioavailability of oral ManNAc has not been determined and there has been no ...
Tahlia R. Meola, Guy Ludbrook, Gianfranco Fornasini, Olga Pavlova, Sumit Jain, Allan M. Evans, Stephanie E. Reuter   +6 more
wiley   +1 more source

Universal School Meal Policies and Perceived Stigma: Quantitative Evidence From Eight US States. [PDF]

J Sch Health
Orta-Aleman D, Zuercher MD, Chapman LE, Schwartz MB, French CD, Patel AI, Ritchie L, Cohen J, Gosliner W.   +8 more
europepmc   +1 more source

Pharmacokinetics, pharmacodynamics and safety of vutiglabridin after multiple oral administrations in healthy female and obese subjects

British Journal of Clinical Pharmacology, EarlyView.
Aims Vutiglabridin (HSG4112) is a novel drug under clinical development for antiobesity treatment. This study aimed to evaluate the pharmacokinetics (PKs) and safety of vutiglabridin after multiple oral administrations in healthy Korean female and obese subjects and explore short‐term pharmacodynamic (PD) responses.
Sooyoun Lee, Hyun Chul Kim, Young Ran Yoon, In‐Jin Jang, Sang‐Ku Yoo, Kyung‐Sang Yu   +5 more
wiley   +1 more source

Circular valorization of Argemone ochroleuca seed meal: biomass fractionation, bioethanol production, and hydrothermal carbonization. [PDF]

Bioresour Bioprocess
Bedru TK, Meshesha BT, Mohammed SA, Demesa AG, Vega SBP, Kebede W, Jayakumar M.   +6 more
europepmc   +1 more source

Population pharmacokinetics of TBAJ‐587 and its main metabolites—Evaluation of different loading dose strategies and early dose selection

British Journal of Clinical Pharmacology, EarlyView.
Background and Aim The rise of drug‐resistant tuberculosis (TB) poses a need for new drugs and combinations. TBAJ‐587, a new diarylquinoline (DARQ), has shown promising efficacy in preclinical studies. This work aimed to describe the pharmacokinetics (PK) of TBAJ‐587 and its metabolites M2 and M3 after single ascending dosing in healthy volunteers and ...
Albin A. M. Leding, Paul Bruinenberg, Almari Conradie, Jerry Nedelman, Antonio Lombardi, Dean Hickman, Ulrika S. H. Simonsson   +6 more
wiley   +1 more source

Mitigating subtherapeutic cabozantinib exposure after prior mitotane therapy in adrenocortical carcinoma: Pharmacological boosting with cobicistat

British Journal of Clinical Pharmacology, EarlyView.
Mitotane is an adrenolytic drug with cytotoxic effects, registered for the treatment of advanced adrenocortical carcinoma (ACC), a rare but aggressive tumour type with a poor prognosis despite treatment. Recently, the oral multi‐kinase inhibitor cabozantinib has shown promising results as a potential second‐line treatment option.
Annemieke M. Peters van Ton, Nielka P. van Erp, Annenienke C. van de Ven, Janneke E. W. Walraven, Loek A. W. de Jong   +4 more
wiley   +1 more source

Temporal meal patterns in relation to diet quality and body mass index: findings from a cross-sectional analysis. [PDF]

Eur J Nutr
Schultz J, Lindroos AK, Tillman I, Moraeus L, Lemming EW.   +4 more
europepmc   +1 more source

Preparation of a Weaning Food Through Enrichment of Maize Meal with Potatoes (Ipomea batatas) Also Known as Orange Fleshed Sweet Potatoes (OFSP)

, 2019
Joseph Mutuku, MW Mwaniki, GW Muiruri
openalex   +2 more sources

Enhanced Vatiquinone Bioavailability With Fatty Meals and Optimal Dosing Schedule

Biopharmaceutics &Drug Disposition, EarlyView.
This investigation discusses two clinical studies. One investigated the effect of fatty meals (≥ 25% fat) on vatiquinone PK exposures, and the other one characterized vatiquinone PK profiles when administered on a TID dosing regimen corresponding to mealtimes. The data support the recommendation of administering vatiquinone with fatty meals (≥ 25% fat)
Lucy Lee, Katsuyuki Murase, Martin Thoolen, Peter Giannousis, Diksha Kaushik, Lee Golden, Ronald Kong   +6 more
wiley   +1 more source