Results 101 to 110 of about 654,693 (352)

Replenishing co‐downregulated miR‐100‐5p and miR‐125b‐5p in malignant germ cell tumors causes growth inhibition through cell cycle disruption

open access: yesMolecular Oncology, EarlyView.
MiR‐99a‐5p/miR‐100‐5p (functionally identical) and miR‐125b‐5p microRNAs are downregulated in malignant germ cell tumors (GCTs). Combination replenishment of these microRNAs using mimics resulted in growth inhibition in representative cell lines, with consequent downregulation of target genes involved in cell cycle (confirmed by flow cytometry) and ...
Marta Ferraresso   +12 more
wiley   +1 more source

Uniform flow distribution to stacked parallel disk channels in a disk shape small-capacity SOFC stack model

open access: yesNihon Kikai Gakkai ronbunshu, 2020
The design of a flow distribution to multiple branch channels is one of the key factors to realize the flow uniformity in a fuel cell stack. Especially for a disk-shape solid oxide fuel cell (SOFC) stack, it is necessary to clarify the optimum structure ...
Kazumi TSUNODA   +2 more
doaj   +1 more source

On the Existence and Uniqueness of Ancient Rescaled Mean Curvature Flows [PDF]

open access: yesarXiv, 2022
We show existence of ancient solutions to the rescaled mean curvature flow starting from a given asymptotically conical self-expander. These are examples of mean curvature flows coming out of cones that are not self-similar. We also show a strong uniqueness theorem when the cone is generic and use it to classify mean curvature flows coming out of ...
arxiv  

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

open access: yesMolecular Oncology, EarlyView.
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam   +2 more
wiley   +1 more source

Swampland, gradient flow and infinite distance

open access: yesJournal of High Energy Physics, 2020
In the first part of this paper we will work out a close and so far not yet noticed correspondence between the swampland approach in quantum gravity and geometric flow equations in general relativity, most notably the Ricci flow.
Alex Kehagias   +2 more
doaj   +1 more source

Mean curvature flow without singularities

open access: yesJournal of Differential Geometry, 2014
19 pages, 4 ...
Sáez Trumper, Mariel Inés Aura   +1 more
openaire   +8 more sources

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

open access: yesMolecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou   +13 more
wiley   +1 more source

Modelling Free Flow Speed on Two-Lane Rural Highways in Bosnia and Herzegovina

open access: yesPromet (Zagreb), 2014
Free flow speed is used as a parameter in transportation planning and capacity analysis models, as well as speed-flow diagrams. Many of these models suggest estimating free flow speed according to measurements from similar highways, which is not a ...
Ivan Lovrić   +2 more
doaj   +1 more source

On the extension of axially symmetric volume flow and mean curvature flow [PDF]

open access: yesarXiv, 2013
We study the provenance of singularity formation under mean curvature flow and volume preserving mean curvature flow in an axially symmetric setting. We prove that if the mean curvature is uniformly bounded on any finite time interval, then no singularities can develop during that time under both mean curvature flow and volume preserving mean curvature
arxiv  

Mean Curvature Flow in a Ricci Flow Background [PDF]

open access: yesCommunications in Mathematical Physics, 2012
Following work of Ecker, we consider a weighted Gibbons-Hawking-York functional on a Riemannian manifold-with-boundary. We compute its variational properties and its time derivative under Perelman's modified Ricci flow. The answer has a boundary term which involves an extension of Hamilton's Harnack expression for the mean curvature flow in Euclidean ...
openaire   +4 more sources

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