Results 81 to 90 of about 901,213 (331)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Enhancing Reliability Indices in Power Distribution Grids Through the Optimal Placement of Redundant Lines Using a Teaching–Learning-Based Optimization Approach

open access: yesEnergies
Given the pressing need to strengthen operational reliability in electrical distribution networks, this study proposes an optimization methodology based on the Teaching–Learning-Based Optimization (TLBO) algorithm for the strategic location of redundant ...
Johao Jiménez   +2 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Research on the intelligent control system for lithium-ion aluminium shell power battery module stacking

open access: yesMechanics & Industry
During the stacking and welding process of lithium-ion aluminium shell power battery modules, the accumulation of cell size errors can easily cause the module length to exceed the tolerance range, affecting the module length qualification rate and the ...
Sheng Qingshan   +3 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Employing Acoustic Emission for Monitoring Oil Film Regimes

open access: yesLubricants, 2013
The major purpose of a gear lubricant is to provide adequate oil film thickness to reduce and prevent gear tooth surface failures. Real time monitoring for gear failures is important in order to predict and prevent unexpected failures which would have a ...
David Mba   +2 more
doaj   +1 more source

Availability and mean time between failures of redundant systems with random maintenance of subsystems [PDF]

open access: yes
It is shown how the availability and MTBF (Mean Time Between Failures) of a redundant system with subsystems maintenanced at the points of so-called stationary renewal processes can be determined from the distributions of the intervals between ...
Schneeweiss, W.
core   +1 more source

Development of an ontology supporting failure analysis of surface safety valves used in Oil & Gas applications [PDF]

open access: yes, 2019
Treball desenvolupat dins el marc del programa 'European Project Semester'.The project describes how to apply Root Cause Analysis (RCA) in the form of a Failure Mode Effect and Criticality Analysis (FMECA) on hydraulically actuated Surface Safety Valves (
Albor Mejia, Dephna   +3 more
core  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

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