Results 31 to 40 of about 372,956 (303)

Contribuições da Teoria da Aprendizagem Significativa para a aprendizagem de conceitos em Botânica = Contributions of the Meaningful Learning Theory to the learning of botany concepts [PDF]

Acta Scientiarum. Education, 2011
O trabalho foi realizado em uma escola da comunidade quilombola Furnas do Dionísio (Jaraguari, Estado do Mato Grosso do Sul). Para sua realização, inicialmente, um teste com questões de Botânica foi aplicado aos alunos para identificar ausência ou ...
Airton José Vinholi Júnior
doaj  

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Conceptos de calor y trabajo en un foro electrónico. Efectos de la autoeficacia computacional

Educación Química, 2013
Concepts of heat and work in an electronic forum. Effects of computer self-efficacy The purpose of this study was to describe the activity performance in an electronic forum on the concepts of work and heat, and their relationship with computer self ...
Martín Enrique Durán-García, Emilse Emperatriz Durán-Aponte   +1 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Meaningful Learning and Its Implications for Language Education in Vietnam

Journal of Language and Education, 2019
This paper attempts to make an argument for meaningful learning as an essential factor in the teaching of English as a foreign language. Meaningful learning rests its theories against cognitive processing. While contemporary literature shows knowledge of
Bui Phu Hung
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Evaluación del desarrollo de competencias a partir de la modelación matemática

Ingenierías USBMed, 2019
In the present study, an educational intervention was carriedout in eleven graders belonging to the St. Vincent de Paul educationalinstitution in the city of Medellín, in order to build the concept ofexponential function in a meaningful way under the ...
Carlos Márquez, Carlos Gaviria, ohanaLópez   +2 more
doaj   +1 more source

Social interaction as a process of encounter or misencounter in the academic learning of adolescents

Revista Perspectivas, 2020
This results article addresses academic learning in adolescent age as a fundamental process to determine the aspects that minimize performance from the interaction with parents, teachers and classmates. The communication breaks with parents, the academic
Maryori Liliana Vera-Angarita, Jhorman Yarokssi Ortega-Ortega, Carolina Ramirez-Martinez, Elkin Gelvez-Almeida, Andrea Lisbeth Hernández-Niño   +4 more
doaj   +1 more source