Results 101 to 110 of about 173,310,524 (306)

Predicting Single‐Cell Perturbation Responses Across Biological Contexts With a Deep Generative Model Integrating Optimal Transport

Advanced Science, EarlyView.
Single‐cell perturbation responses are predicted across held‐out biological contexts using scPILOT, a query‐conditioned two‐stage latent response‐transfer framework. A shared latent representation supports cell‐level response estimation by latent optimal transport, followed by Leiden‐localized query‐specific transfer and adaptive weighting.
Jialiang Wang, Ziqi Liu, Zhengqian Zhang, Yikun Cao, Junjun Ren, Peng Cheng, Jingjing Tian, Lingyun Xie, Xin Lu, Zhanwei Du, Yongzhuang Liu   +10 more
wiley   +1 more source

A simple model to include fuzziness in the seismic fragility curve and relevant effect compared with randomness

, 2011
Damage has to be quantified in civil structures to assess their seismic performance and risk and loss on a regional scale. Fragility curves have proved to be suitable for coping with randomness inherent in such an issue. Recently, the cognitive source of
Felice Colangelo, COLANGELO, Felice
core   +1 more source

Modeling Words for Qualitative Distance Based on Interval Type-2 Fuzzy Sets

ISPRS International Journal of Geo-Information, 2018
Modeling qualitative distance words is important for natural language understanding, scene reconstruction and many decision support systems (DSSs) based on a geographic information system (GIS).
Jifa Guo, Shihong Du
doaj   +1 more source

Spatiotemporal Multi‐Omic Mapping Reveals Liver‐Muscle Metabolic Crosstalk in Cancer Cachexia

Advanced Science, EarlyView.
The interactive CCAtlas platform delineates cross‐species, spatiotemporal, and sex‐specific molecular dynamics and metabolic rewiring across organs during cancer cachexia. Hepatic Gamt downregulation curtails hepatic creatine synthesis to trigger systemic creatine insufficiency and consequent skeletal muscle atrophy in LLC tumour‐bearing mice ...
Zihan Tian, Qianyu Wang, Wenyan Gao, Xianfeng Li, Jiawen Fan, Xiaoliang Wu, Siqi Liu, Xiangdong Ming, Danna Yeerken, Mutian Shen, Qingjie Min, Qimin Zhan, Yan Wang   +12 more
wiley   +1 more source

Reversing Macrophage Immunometabolic Dysfunction in Prolonged Infections Via a Glutaminolysis‐Fueled Restoration‐Based Hierarchically Selective Therapeutic System

Advanced Science, EarlyView.
A hierarchically selective immunotherapeutic nanoplatform, mGls@HEV‐MTP, selectively restores macrophage immunocompetence through GLS1‐mediated restoration of glutaminolysis‐fueled anaplerosis. Concurrently, it renders Staphylococcus aureus (S. aureus) more readily recognizable to the metabolically reprogrammed macrophages, thereby facilitating ...
Weinan Yang, Zihao An, Honglu Cai, Congsun Li, Jiaxuan Zou, Wushi Cui, Wentao Chen, Tao Zhang, Shicheng Wang, Zizhan Su, Jian Xiao, Tao Sun, Bin Hu, Min Cheng, Zhongru Gou, Jianbin Xu, An Liu, Haobo Wu   +17 more
wiley   +1 more source

A Review of Cluster Validation with an Example of Type-2 Fuzzy Application in R

, 2013
Interval valued type-2 fuzziness can be represented by means of membership functions obtained with upper and lower values of the level of fuzziness. These upper and lower values for the level of fuzziness in FCM algorithm were obtained in our previous ...
Özkan, İ., Türkşen, I. Burhan, Ibrahim Ozkan, I. Burhan Türkşen   +3 more
core   +1 more source

Improved TOPSIS and CRITIC Methods for Failure Mode and Effects Analysis Based on Z-Number Theory

Machines
Failure mode and effects analysis (FMEA), as a means of identifying, preventing, and controlling potential system failures, has been widely applied in many industries. However, the classic FMEA method has several drawbacks in practical applications, such
Daijun Deng, Shuai Jiang, Xinlong Li, Yu Liu, Ning Wei, Fafa Chen   +5 more
doaj   +1 more source

Multiple Criteria Decision Analysis Using Correlation-Based Precedence Indices Within Pythagorean Fuzzy Uncertain Environments

International Journal of Computational Intelligence Systems, 2018
The theory of Pythagorean fuzzy sets possesses significant advantages in handling vagueness and complex uncertainty. Additionally, Pythagorean fuzzy information is useful to simulate the ambiguous nature of subjective judgments and measure the fuzziness ...
Jih-Chang Wang, Ting-Yu Chen
doaj   +1 more source

Force‐Electric Nanotentacles of Tantalum Implant Accelerate Cellular Energy Metabolism/Crosstalk for Immunomodulation‐Vascularized Bone Integration

Advanced Science, EarlyView.
A biomimetic force‐electric nanotentacle‐enabled tantalum (Ta) implant with surface‐nanostructured LiTaO3 (n‐LiTaO3) was first developed via laser nanofabrication combined with Li+‐induced in situ reaction, enabling the transduction of ultrasound into bioelectrical cues.
Taixing Zhang, Ke Ma, Kangqing Zuo, Pandong Lin, Tailong Zhang, Rongliang Ding, Linbo Zhang, Aonan Li, Yinchuan Wang, Yanling Huang, Jichao Feng, Guiyong Xiao, Yupeng Lu, Bing Han, Zhiqiang Wang, Ningbo Li   +15 more
wiley   +1 more source

Medical Pattern Recognition: Applying an Improved Intuitionistic Fuzzy Cross-Entropy Approach

Advances in Fuzzy Systems, 2012
One of the toughest challenges in medical diagnosis is the handling of uncertainty. Since medical diagnosis with respect to the symptoms uncertain, they will be assumed to have an intuitive nature.
Kuo-Chen Hung
doaj   +1 more source