Results 101 to 110 of about 47,514 (263)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Testing measurement equivalence of neurocognitive assessments across language in the Hispanic Community Health Study/Study of Latinos. [PDF]

Neuropsychology, 2021
Goodman ZT, Llabre MM, González HM, Lamar M, Gallo LC, Tarraf W, Perreira KM, López-Cevallos DF, Vásquez PM, Medina LD, Perera MJ, Zeng D, Bainter SA.   +12 more
europepmc   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Examining the measurement equivalence of the Maslach Burnout Inventory across age, gender, and specialty groups in US physicians. [PDF]

J Patient Rep Outcomes, 2021
Brady KJS, Sheldrick RC, Ni P, Trockel MT, Shanafelt TD, Rowe SG, Kazis LE.   +6 more
europepmc   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Equivalence of low-cost PM10 concentration measuring devices with a reference method using various correction functions

Economics and Environment
The aim of the study was to build a corrective model that can be used in the analysed devices and to assess the impact of such a model on the values of the measured concentrations. The novelty of this study is the test of equivalence with the equivalent
Tomasz Owczarek, Mariusz Rogulski, Piotr O. Czechowski, Artur Badyda, Ernest Czermański   +4 more
doaj   +1 more source

On Two Equivalence Relations between Measures

The Annals of Mathematical Statistics, 1966
Let $I$ be the closed unit interval, with the usual topology; II the set of probabilities on $I$, with the weak$^\ast$ topology: $\mu_n \rightarrow \mu$ in II if and only if $\int_I f d\mu_n \rightarrow \int_I f d\mu$ for each continuous, real-valued $f$ on $I$.
openaire   +2 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Does scrolling affect measurement equivalence of electronic patient-reported outcome measures (ePROM)? Results of a quantitative equivalence study. [PDF]

J Patient Rep Outcomes, 2021
Shahraz S, Pham TP, Gibson M, De La Cruz M, Baara M, Karnik S, Dell C, Pease S, Nigam S, Cappelleri JC, Lipset C, Zornow P, Lee J, Byrom B.   +13 more
europepmc   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source