Results 141 to 150 of about 898,493 (283)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Use of mechanically-activated kaolin to replace ball clay in engobe for a ceramic tile

Cerâmica
Ceramic engobe is an intermediate layer between the substrate and the glaze of a ceramic tile. It is basically composed by plastic material, clays, and non-plastic material, feldspar and frit.
E. Becker, J. Jiusti, F. D. Minatto, D. G. G. Delavi, O. R. K. Montedo, A. de Noni Jr.   +5 more
doaj   +1 more source

The Effect of Mechanical Activation of Fly Ash on Cement-Based Materials Hydration and Hardened State Properties. [PDF]

Materials (Basel), 2023
Akmalaiuly K, Berdikul N, Pundienė I, Pranckevičienė J.   +3 more
europepmc   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Formation of Structure of Highly Filled UHMWPE Composites under Conditions of Intensive Mechanical Activation for Radiation Protective Materials

Механика машин, механизмов и материалов, 2019
The structural changes of the ultrahigh molecular weight polyethylene (UHMWPE) filled by 70 wt.% of the ultradisperse mechanocomposites Fe/M (M = HfC (12 об.%), TiC (26 об.%), TiB2 (27 об.%), B4C (51 об.%)) and activated by the treatment in the spherical
Viktor I. Zhornik, Svetlana A. Kovaliova, Tatyana F. Grigoryeva, Tatyana Yu. Kiseleva, Marat A. Belotserkovsky, Igor I. Taran, Igor V. Valkovich, Petr A. Vityaz, Nikolay Z. Lyakhov   +8 more
doaj  

An influence of mechanical activation on the selectivity of tetrahedrite acid leaching [PDF]

Acta Montanistica Slovaca, 2005
Sulphidic mineral - tetrahedrite Cu12Sb4S13 was subjected to leaching in a H2SO4 medium. Physico-chemical changes of a mechanically activated mineral were investigated before and after leaching using the infrared spectroscopy and the scanning electron ...
Jaroslav Briančin, Marcela Achimovičová, Peter Baláž   +2 more
doaj  

MULTITASK LEARNING FOR IMPROVED LATE MECHANICAL ACTIVATION DETECTION OF HEART FROM CINE DENSE MRI. [PDF]

Proc IEEE Int Symp Biomed Imaging, 2023
Xing J, Wang S, Bilchick KC, Epstein FH, Patel AR, Zhang M.   +5 more
europepmc   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Investigating the Effect of Co-Cr-Sn Ions Substitution on Microstructure and Magnetic Properties of M-type Barium Hexaferrites

Journal of Advanced Materials in Engineering, 2016
In this research, investigation of the microstructure and magnetic properties of doped barium hexaferrite with cobalt, chromium and tin with BaCoxCrxSnxFe12-3xO19 (x=0.3,0.5) formula, was performed using solid state method.
S. S. Seyyed Afghahi, M. Jafarian, M. Salehi   +2 more
doaj  

A modular spring-loaded actuator for mechanical activation of membrane proteins. [PDF]

Nat Commun, 2022
Mills A, Aissaoui N, Maurel D, Elezgaray J, Morvan F, Vasseur JJ, Margeat E, Quast RB, Lai Kee-Him J, Saint N, Benistant C, Nord A, Pedaci F, Bellot G.   +13 more
europepmc   +1 more source