Results 101 to 110 of about 4,432,927 (296)

Damage localization using experimental modal parameters and topology optimization [PDF]

open access: yes, 2010
This work focuses on the developement of a damage detection and localization tool using the Topology Optimization feature of MSC.Nastran. This approach is based on the correlation of a local stiness loss and the change in modal parameters due to damages ...
Niemann, Hanno   +7 more
core   +1 more source

DNA damage and repair mechanism. [DNA damage and repair mechanisms] [PDF]

open access: yes, 1976
The ability of cells to survive in an environment specifically damaging to its DNA can be attributed to a variety of inherent repair mechanisms. This is a form of repair in which alterations are directly reversed to their original form. This reversibility is exemplified by the photoreactivation of ultraviolet-induced pyrimidine dimers.
openaire   +2 more sources

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

open access: yesFEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda   +2 more
wiley   +1 more source

Damage location method for thin composites structures - application to an aircraft door [PDF]

open access: yes, 2013
Piezoelectric sensors are widely used for Structure Health Monitoring (SHM) technique due to their high-frequency capability. In particular, electromechanical impedance (EMI) techniques give simple and low cost solutions for detecting damage in composite
Pommier-Budinger, Valérie   +3 more
core  

Use of the X-ray technique to evaluate the internal morphology of seeds of green manure species [PDF]

open access: yesJournal of Seed Science
: Image analysis through X-ray technique has been receiving great attention due to its importance in identifying internal damage in seeds quickly and accurately, in addition to being a non-destructive method.
Marina Barros Zacharias   +4 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Three-dimension elastic-plastic damage constitutive model for intact rock

open access: yesYantu gongcheng xuebao, 2017
Based on the concept of true stress and the strain equivalence hypothesis, a three-dimension elastic-plastic damage constitutive model for rock is established.
DU Xiu-li 1, HUANG Jing-qi 1,2, JIN Liu 1, ZHAO Mi 1
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

An Experimental Validation of a Statistical-Based Damage Detection Approach, January 2011 [PDF]

open access: yes, 2011
In this work, a previously-developed, statistical-based, damage-detection approach was validated for its ability to autonomously detect damage in bridges.

core  

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

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