Results 161 to 170 of about 4,432,927 (296)

Nanohydroxyapatite as a Biomaterial for Peripheral Nerve Regeneration after Mechanical Damage-In Vitro Study. [PDF]

Int J Mol Sci, 2021
Wiatrak B, Sobierajska P, Szandruk-Bender M, Jawien P, Janeczek M, Dobrzynski M, Pistor P, Szelag A, Wiglusz RJ.   +8 more
europepmc   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

Molecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both, Ingrid A. M. Derks, Raphaël Vanleyssem, Marine Leclercq, Najla El Hachem, Pierre Close, Eric Eldering, Marco Vincent Haselager   +7 more
wiley   +1 more source

Electrochemical Impedance Spectroscopy as a Tool to Monitor Degradation, Fouling and Mechanical Damage in Ion-Selective Electrode Membranes. [PDF]

Sensors (Basel)
Drużyńska M, Lenar N, Paczosa-Bator B.
europepmc   +1 more source

Does Ovarian Endometriosis Increase Oocyte Sensitivity to ICSI-Induced Mechanical Damage? [PDF]

J Clin Med, 2021
Scarafia C, Masciovecchio M, Canosa S, Carosso AR, Gennarelli G, Revelli A, Benedetto C.   +6 more
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Hydraulic-Mechanical-Damage Multifield Coupling Control Mechanism and Gas Production Prediction of Fracturing in Tectonically Deformed Coal Seam. [PDF]

ACS Omega
Yan Z, Xie H, Sang S, Zhou X, Liu S, Han S, Huang F, Wang W, Chen J, Jiang B.   +9 more
europepmc   +1 more source

Influence of Mechanical Damage under Repeated Loading on the Resistance of Geogrids against Abrasion. [PDF]

Materials (Basel), 2021
Carlos DM, Almeida F, Carneiro JR, Lopes ML.   +3 more
europepmc   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Mechanical damage and thermal effect induced by ultrasonic treatment in olive leaf tissue. Impact on polyphenols recovery. [PDF]

Ultrason Sonochem, 2022
Abi-Khattar AM, Boussetta N, Rajha HN, Abdel-Massih RM, Louka N, Maroun RG, Vorobiev E, Debs E.   +7 more
europepmc   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source