Results 71 to 80 of about 4,432,927 (296)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Damage monitoring in sandwich beams by modal parameter shifts: a comparative study of burst random and sine dwell vibration testing [PDF]
, 2010 This paper presents an experimental study on the effects of multi-site damage on the vibration response of honeycomb sandwich beams, damaged by two different ways i.e., impact damage and core-only damage simulating damage due to bird or stone impact or ...
Morlier, Joseph +5 more
core +1 more source
MECHANISM OF ALCOHOLIC TESTICULAR DAMAGE
The Japanese Journal of Urology, 1992 To observe the mechanism of alcoholic testicular damage, in a previous experiment we used weanling male SD rats aged 45 days, weighing about 200 g, and fed a liquid diet (Lieber's) containing 5% ethanol. The latter accounted for 36% of total caloric intake for 7 weeks, but did not result in testicular atrophy.
Shirai, Takashi, Ikemoto, Isao
openaire +3 more sources
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Mechanical and Thermal Damage of Hard Chromium Coatings on 416 Stainless Steel
, 2016 Hard chromium coating has a wide range of applications in automotive and aerospace industries. However, the open literature lacks a comprehensive study on the failure of hard chromium coatings.
Almotairi, Abdullah
core
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
A new chemo-mechanical model of damage in concrete under sulfate attack
, 2016 Damage evolution is detected via the degradation of modulus of concrete immersed in sulfate solution. The mechanism of the damage is investigated by using SEM method, and it is proved that the internal expansion stress induced by delayed ettringite leads
陈建康 +3 more
core +1 more source
Agricultura Tropica et Subtropica, 2012 Physical control methods are preferred in post-harvest management of insect pests because chemical intervention is extremely hazardous. Use of audible sound waves in insect pest intervention is a novel idea which has not been popular hitherto. An attempt
Jinham Alfred Premjith +3 more
doaj +1 more source