Results 71 to 80 of about 459,298 (264)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The Properties of Damaged Starch Granules: The Relationship Between Granule Structure and Water–Starch Polymer Interactions

Foods
The morphology of wheat starch granules with different damaged starch (DS) content was analyzed using a particle size analyzer and scanning electron microscopy (SEM); the granular structure was studied using FT-IR spectroscopy and X-ray diffraction (XRD);
Andrés Gustavo Teobaldi, Esteban Josué Carrillo Parra, Gabriela Noel Barrera, Pablo Daniel Ribotta   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Quality and Quantity Losses of Tomatoes Grown by Small-Scale Farmers Under Different Production Systems

Horticulturae
Postharvest losses amongst small-scale farmers in developing countries are high due to inadequate resources and infrastructure. Among the various affected crops, tomatoes are particularly vulnerable; however, studies on postharvest losses of most fruits ...
Tintswalo Molelekoa, Edwin M. Karoney, Nazareth Siyoum, Jarishma K. Gokul, Lise Korsten   +4 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

ESTUDIO PRELIMINAR DE LA RESISTENCIA MECÁNICA A LA FRACTURA Y FUERZA DE FIRMEZA PARA FRUTA DE UCHUVA (Physalis peruviana L.) PRELIMINARY STUDY OF MECHANICAL RESISTANCE TO FRACTURE AND FIRMNESS FORCE FOR UCHUVA (Physalis peruviana L) FRUITS

Revista Facultad Nacional de Agronomía Medellín, 2007
Se hizo la caracterización reológica de la uchuva (Physalis peruviana L.) a través de la respuesta mecánica bajo ensayos de compresión unidireccional a pruebas de firmeza y fractura, para 3 grados de madurez (verde, pintón y maduro) y los días ...
Héctor José Ciro Velasquez, Omar Hideki Buitrago Giraldo, Sebastián Adolfo Pérez Arango   +2 more
doaj  

Establish methods to improve the efficiency of tissue-free genetic transformation of medicinal plants through mechanical damage

Medicinal Plant Biology
Medicinal plants are widely used in various fields, such as medicine, fragrance production, cosmetics and food. However, only a small number of medicinal plants can be genetically modified, making it difficult to improve these plants through genetic ...
Jingyi Zhang, Bisheng Huang, Sainan Peng, Qianwen Zhang, Jinxin Li, Dahui Liu, Yuhuan Miao   +6 more
doaj   +1 more source

A VIBRATIONAL DAMAGE MODEL FOR PEARS BASED ON FATIGUE ACCUMULATIVE DAMAGE THEORY [PDF]

Engenharia Agrícola
Fatigue vibration is a primary cause of fruit damage during transportation. Drawing on the Palmgren–Miner fatigue accumulation damage theory and the correlation between fruit vibration damage characteristics and external vibration excitation, this paper ...
Chenxu Zhao, Yuchi Li, Xue Huang, Shujie Song   +3 more
doaj   +1 more source