Results 1 to 10 of about 110,588 (202)

Effect of Mechanical Microenvironment on Collagen Self-Assembly In Vitro [PDF]

Journal of Functional Biomaterials, 2023
Collagen, as a structural protein, is widely distributed in the human body. Many factors influence collagen self-assembly in vitro, including physical-chemical conditions and mechanical microenvironment, and play a key role in driving the structure and ...
Leihan Han, Jiexiang Lin, Chengfei Du, Chunqiu Zhang, Xin Wang, Qijin Feng   +5 more
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Extracellular vesicles originating from the mechanical microenvironment in the pathogenesis and applications for cardiovascular diseases [PDF]

Regenerative Therapy
The mechanical microenvironment plays a crucial regulatory role in the growth and development of cells. Mechanical stimuli, including shear, tensile, compression, and extracellular matrix forces, significantly influence cell adhesion, migration ...
Yu Zeng, Xiaodong Cui, Hong Li, Yanhui Wang, Min Cheng, Xiaoyun Zhang   +5 more
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Boosting antitumor efficacy of nanoparticles by modulating tumor mechanical microenvironment [PDF]

EBioMedicine
Summary: Nanoparticles have shown great potential for tumor targeting delivery via enhanced permeability and retention effect. However, the tumor mechanical microenvironment, characterized by dense extracellular matrix (ECM), high tumor stiffness and ...
Xiaoqiong Zhang, Xiaojuan Zhang, Tuying Yong, Lu Gan, Xiangliang Yang   +4 more
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The important role of cellular mechanical microenvironment in engineering structured cultivated meat: Recent advances [PDF]

Current Research in Food Science
Cultivated meat (CM) provides a potential solution to meet the rising demand for eco-friendly meat supply systems. Recent efforts focus on producing CM that replicates the architecture and textural toughness of natural skeletal muscle.
Pan Zhang, Xu Zhao, Shiling Zhang, Guoliang Li, Adam C. Midgley, Yapeng Fang, Mouming Zhao, Katsuyoshi Nishinari, Xiaolin Yao   +8 more
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Functions and clinical significance of mechanical tumor microenvironment: cancer cell sensing, mechanobiology and metastasis

Cancer Communications, 2022
Dynamic and heterogeneous interaction between tumor cells and the surrounding microenvironment fuels the occurrence, progression, invasion, and metastasis of solid tumors.
Hanying Zhou, Meng Wang, Yixi Zhang, Qingqing Su, Zhengxin Xie, Xiangyan Chen, Ran Yan, Ping Li, Tingting Li, Xiang Qin, Hong Yang, Chunhui Wu, Fengming You, Shun Li, Yiyao Liu   +14 more
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Mechanical Microenvironment-Dependent Tumor Growth Intervention: Recent Advances and Translational Outlook [PDF]

Technology in Cancer Research & Treatment
In recent years, increasing attention has been directed toward the mechanical microenvironment, which has become a major research focus in elucidating the mechanisms underlying tumor progression.
Danjing Liang MS, Huan Zhou PhD, Xinye Ni PhD   +2 more
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An overview of mechanical microenvironment and mechanotransduction in intervertebral disc degeneration [PDF]

Experimental and Molecular Medicine
Cellular mechanotransduction, essential for many biological functions, involves the conversion of mechanical signals into biochemical signals related to cell activities and metabolism.
Wencan Ke, Hanpeng Xu, Chengyi Zhang, Zhiwei Liao, Huaizhen Liang, Bide Tong, Feijun Yuan, Kun Wang, Wenbin Hua, Bingjin Wang, Cao Yang   +10 more
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Insights into the mechanical microenvironment within the cartilaginous endplate: An emerging role in maintaining disc homeostasis and normal function [PDF]

Heliyon
Biomechanical factors are strongly linked with the emergence and development of intervertebral disc degeneration (IVDD). The intervertebral disc (IVD), as a unique enclosed biomechanical structure, exhibits distinct mechanical properties within its ...
Pan Xiang, Zong-Ping Luo, Yan-Jun Che
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Mechanical cues in tumor microenvironment on chip

Biosensors and Bioelectronics: X, 2023
Mechanical cues from the tumor microenvironment (TME) can influence cell behaviors and have been indicated to play a pivotal role in tumor initiation, progression, and metastasis.
Zhiru Zhou, Theadora Vessella, Pengbo Wang, Feiyun Cui, Qi Wen, Hong Susan Zhou   +5 more
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The mechanical microenvironment and lung stem cell fate [PDF]

Frontiers in Cell and Developmental Biology
The lung is a complex, branched organ that follows an intricate and well-coordinated developmental process to generate dozens of different cell types. Several protocols have been established to differentiate stem cells into the cell types of the lung in ...
Evelyn S. Navarro Salazar, Celeste M. Nelson, Celeste M. Nelson   +2 more
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