Results 11 to 20 of about 110,588 (202)
Mechanoresponsive reprogramming of tumor-associated macrophages during cancer progression [PDF]
Frontiers in Cell and Developmental BiologyTumor-associated macrophages (TAMs) are critical regulators of the tumor microenvironment. They exhibit diverse pro-tumorigenic and antitumor phenotypes depending on their monocyte-derived or tissue-resident origins.
Dayeon Kim +6 more
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A mechanical stimulation-related gene signature predicts prognosis, reflects immune microenvironment remodeling, and identifies COL22A1 as a potential therapeutic target in lung adenocarcinoma [PDF]
Frontiers in ImmunologyBackgroundMechanical stimulation is a key biomechanical characteristic of the tumor microenvironment and is involved in tumor progression, immune microenvironment remodeling, and therapy resistance.
Weihao Zhang +4 more
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Adaptable hydrogel with reversible linkages for regenerative medicine: Dynamic mechanical microenvironment for cells. [PDF]
Bioact Mater, 2021 Tong Z +6 more
europepmc +2 more sources
Membranes, 2022 Articular cartilage and their chondrocytes are physiologically submitted to diverse types of mechanical cues. Chondrocytes produce and maintain the cartilage by sensing and responding to changing mechanical loads.
Min Zhang +4 more
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Harnessing mechanical cues in the cellular microenvironment for bone regeneration
Frontiers in Physiology, 2023 At the macroscale, bones experience a variety of compressive and tensile loads, and these loads cause deformations of the cortical and trabecular microstructure.
Timothy O. Josephson +4 more
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Biomedicines, 2022 FoxL1+telocytes (TCFoxL1+) are novel gastrointestinal subepithelial cells that form a communication axis between the mesenchyme and epithelium. TCFoxL1+ are strategically positioned to be key contributors to the microenvironment through production and ...
Alain B. Alfonso +6 more
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Advanced Science, 2023 Dynamically evolving adhesions between cells and extracellular matrix (ECM) transmit time‐varying signals that control cytoskeletal dynamics and cell fate. Dynamic cell adhesion and ECM stiffness regulate cellular mechanosensing cooperatively, but it has
Zheng Zhang +18 more
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Cancer Biology & Medicine, 2023 Mechanical forces in the tumor microenvironment (TME) are associated with tumor growth, proliferation, and drug resistance. Strong mechanical forces in tumors alter the metabolism and behavior of cancer cells, thus promoting tumor progression and ...
Pengfei Zhu +5 more
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Exosome-mediated transduction of mechanical force regulates prostate cancer migration via microRNA
Biochemistry and Biophysics Reports, 2022 Physical cues in the extracellular microenvironment regulate cancer cell metastasis. Functional microRNA (miRNA) carried by cancer derived exosomes play a critical role in extracellular communication between cells and the extracellular microenvironment ...
Zhixiao Liu +5 more
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Frontiers in Oncology, 2022 Gliomas represent the most common malignant primary brain tumors, and a high-grade subset of these tumors including glioblastoma are particularly refractory to current standard-of-care therapies including maximal surgical resection and chemoradiation ...
Adip G. Bhargav +3 more
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