Results 91 to 100 of about 8,095,394 (310)

Thermo-mechanical response, anisotropy, and texture evolution of two overaged Al 7056 alloy plates in T761 and T721 tempers: Experiments and Modeling

open access: yes, 2020
The purpose of this research is to investigate the thermo-mechanical response, anisotropy, and texture evolution of two overaged AA7056 plates, in T761 and T721 tempers, over a wide range of strain rates (10-4 3 x 103 s-1) and temperatures (22 300?C)
Ku, Angela
core   +1 more source

Evaluation of Grouting Effectiveness on Cracks in Cement-Stabilized Macadam Layer Based on Pavement Mechanical Response Using FBG Sensors

open access: yesApplied Sciences
Cracking in semi-rigid cement-stabilized macadam bases constitutes a prevalent distress in asphalt pavements. While extensive research exists on grouting materials for crack rehabilitation, quantitative assessment methodologies for treatment efficacy ...
Min Zhang   +4 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

The mechanical response of the ovine lumbar anulus fibrosus to uniaxial, biaxial and shear loads [PDF]

open access: yes, 2010
Analytical and computational models of the intervertebral disc (IVD) are commonly employed to enhance understanding of the biomechanics of the human spine and spinal motion segments.
Tevelen, Gregory   +5 more
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Mechanical Response of Super-large Diameter Shield Tunnel Structure under Construction Load Coupled Action

open access: yesChengshi guidao jiaotong yanjiu
[Objective] During construction, super-large diameter shield tunnels are subjected to multiple forces which may easily cause structural damage and waste leakage.
MA Xiaobo
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Topography and mechanical properties of single molecules of type I collagen using atomic force microscopy [PDF]

open access: yes, 2005
Although the mechanical behavior of tendon and bone has been studied for decades, there is still relatively little understanding of the molecular basis for their specific properties.
Bozec, L.   +5 more
core   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Numerical Analysis of Reinforced Concrete Frame Structures with Graphene Oxide and Study of the Earthquake-Resistant Behavior of the Structures Considering the Earthquake in Turkey and Syria (2023)

open access: yesFibers
The earthquake of 6 February 2023, in Turkey and Syria, was catastrophic for many existing buildings. Various reasons have been given to try to understand what happened, since after 2000, changes in construction methods were introduced in this area, with
D. Domínguez-Santos
doaj   +1 more source

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