Results 91 to 100 of about 2,329,116 (298)

Nonlinear Mechanical Response of DNA due to Anisotropic Bending Elasticity

open access: yes, 2002
The response of a short DNA segment to bending is studied, taking into account the anisotropy in the bending rigidities caused by the double-helical structure. It is shown that the anisotropy introduces an effective nonlinear twist-bend coupling that can
Balaeff   +19 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Nanorheology of viscoelastic shells: Applications to viral capsids

open access: yes, 2007
We study the microrheology of nanoparticle shells [Dinsmore et al. Science 298, 1006 (2002)] and viral capsids [Ivanovska et al. PNAS 101, 7600 (2004)] by computing the mechanical response function and thermal fluctuation spectrum of a viscoelastic ...
Alex J. Levine   +14 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Numerical Analysis of Reinforced Concrete Frame Structures with Graphene Oxide and Study of the Earthquake-Resistant Behavior of the Structures Considering the Earthquake in Turkey and Syria (2023)

open access: yesFibers
The earthquake of 6 February 2023, in Turkey and Syria, was catastrophic for many existing buildings. Various reasons have been given to try to understand what happened, since after 2000, changes in construction methods were introduced in this area, with
D. Domínguez-Santos
doaj   +1 more source

A Stochastic Multi-scale Approach for Numerical Modeling of Complex Materials - Application to Uniaxial Cyclic Response of Concrete

open access: yes, 2016
In complex materials, numerous intertwined phenomena underlie the overall response at macroscale. These phenomena can pertain to different engineering fields (mechanical , chemical, electrical), occur at different scales, can appear as uncertain, and are
Adnan Ibrahimbegovic   +25 more
core   +3 more sources

Mechanisms responsible for coronary vasospasm

open access: yesJournal of the American College of Cardiology, 1986
Studies have been conducted on isolated segments of the left circumflex coronary artery of the dog to gain information on the mechanism or mechanisms of vasospasm. Coronary arteries contain both postjunctional alpha 1- and beta 1-adrenoceptors, and both are accessible to norepinephrine released from the sympathetic nerves.
Shepherd, T, Vanhoutte, PM
openaire   +4 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Influence of built-in strain sensor on the mechanical properties of asphalt mixture

open access: yes工程科学学报
The pursuit of intelligence and smartness in road infrastructure is critical for the advancement of road engineering. Embedded strain sensors serve as a vital tool for sensing strain within pavement structures.
Li LIU   +5 more
doaj   +1 more source

Mechanisms of the Sympathoadrenal Response to Hypoglycemia

open access: yes, 1997
Publisher Summary The sympathoadrenal response to hypoglycemia plays a key role in glucose counterregulation. In insulin-dependent diabetes, its role becomes even more critical because the glucagon response to hypoglycemia is lost after a short duration of diabetes.
D G, Maggs, R S, Sherwin
openaire   +2 more sources

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