Results 101 to 110 of about 2,329,116 (298)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Meitan xuebaoAccelerated instability and failure of surrounding water-rich mudstone in roadway under dynamic loading has become a prominent problem in deep coal resource mining, and it is of great significance to study the damage mechanism of water-containing ...
Guichen LI +5 more
doaj +1 more source
Mechanical response of large-diameter shield tunnels during assembly
Yantu gongcheng xuebao, 2019 Based on loading analysis of shield tunnel segments during the assembly phase, a finite difference model is established for segmental lining structure in assembly stage.
FENG Kun 1, XU Kai 1, PENG Zu-zhao 2, ZHOU Zi-yang 1, HE Chuan 1, XIAO Ming-qing 3
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Disorder, pre-stress and non-affinity in polymer 8-chain models
, 2015 To assess the role of single-chain elasticity, non-affine strain fields and pre-stressed reference states we present and discuss the results of numerical and analytical analyses of modified 8-chain Arruda-Boyce model for cross-linked polymer networks ...
Cioroianu, Adrian +2 more
core +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Mechanisms of subliminal response priming
Advances in Cognitive Psychology, 2007 Subliminal response priming has been considered to operate on several stages, e.g. perceptual, central or motor stages might be affected. While primes' impact on target perception has been clearly demonstrated, semantic response priming recently has been thrown into doubt (e.g. Klinger, Burton, & Pitts, 2000).
Kiesel, Andrea +2 more
openaire +3 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Applied Sciences, 2019 For water transmission tunnels constructed in high-risk seismic regions of western China, active faults pose threats of serious ruptures to the tunnels. To overcome this issue, a 3D discrete-continuum coupling approach is introduced into the study.
Yalina Ma +3 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source