Results 101 to 110 of about 8,095,394 (310)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Influence of built-in strain sensor on the mechanical properties of asphalt mixture
工程科学学报The pursuit of intelligence and smartness in road infrastructure is critical for the advancement of road engineering. Embedded strain sensors serve as a vital tool for sensing strain within pavement structures.
Li LIU +5 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Connecticut State Emergency Response Commission [web site] [Harvested on 2012: Aug. 10]
, 2012 Updated irregularly; Began in 2002?; Title from home page (publisher's Web site, viewed June 1, 2011).; At head of title: State of Connecticut.; Official website of the Connecticut State Emergency Response Commission.
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Investigation of mechanical properties of recycled polypropylene [PDF]
, 2007 Every year there is an Increase in the amount of plastics formed by all types of processes, such as extrusion, blow moulding, injection moulding, etc The recycling of waste plastic materials 1s developing at a manufacturing process scale, and rts arm is ...
Elgammudi, Lutfi Furji
core +1 more source
Meitan xuebaoAccelerated instability and failure of surrounding water-rich mudstone in roadway under dynamic loading has become a prominent problem in deep coal resource mining, and it is of great significance to study the damage mechanism of water-containing ...
Guichen LI +5 more
doaj +1 more source
Mechanical response of large-diameter shield tunnels during assembly
Yantu gongcheng xuebao, 2019 Based on loading analysis of shield tunnel segments during the assembly phase, a finite difference model is established for segmental lining structure in assembly stage.
FENG Kun 1, XU Kai 1, PENG Zu-zhao 2, ZHOU Zi-yang 1, HE Chuan 1, XIAO Ming-qing 3
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Molecular mechanisms involved in cell response to mechanical forces [PDF]
, 2011 New devices were designed to generate a localized mechanical vibration of flexible gels where human umbilical vein endothelial cells (HUVECs) were cultured.
Nishitani, Wagner S.
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, 2017 The identification of the mechanical parameters of the viscoelastic core layer is of great significance for the modeling and damping design of the constrained layer damping (CLD) composite structure.
Zhuo Wang +3 more
core +1 more source