Results 81 to 90 of about 2,329,116 (298)
Mechanical Response of Deep Soft-Rock Tunnels Under Different Rock Bolt Configurations: Model Tests
BuildingsDeep soft-rock tunnels are prone to large deformations and structural damage. This study used the Guanyinping Tunnel as a prototype and conducted 1/50-scale progressive loading model tests under three support configurations: rock-bolt-free, equal-length ...
Yue Yang
doaj +1 more source
Isostaticity and Mechanical Response of Two-Dimensional Granular Piles
, 2004 We numerically study the static structure and the mechanical response of two-dimensional granular piles. The piles consist of polydisperse disks with and without friction.
Akihiro Kasahara +2 more
core +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
AnimalsPolo is a high-speed equestrian sport that imposes mechanical demands on horses and turf, yet limited research has examined the functional behavior of polo playing surfaces.
María Alejandra Blanco +3 more
doaj +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Applied SciencesCracking in semi-rigid cement-stabilized macadam bases constitutes a prevalent distress in asphalt pavements. While extensive research exists on grouting materials for crack rehabilitation, quantitative assessment methodologies for treatment efficacy ...
Min Zhang +4 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Tension mediated nonlinear coupling between orthogonal mechanical modes of nanowire resonators
, 2018 We study the nonlinear coupling between orthogonal flexural modes of doubly clamped InAs nanowire resonators. The two orthogonal modes are formed by the symmetry breaking and lifting of degeneracy of the fundamental mode.
Bhushan, Anand +2 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Chengshi guidao jiaotong yanjiu[Objective] During construction, super-large diameter shield tunnels are subjected to multiple forces which may easily cause structural damage and waste leakage.
MA Xiaobo
doaj +1 more source