Results 61 to 70 of about 779,679 (267)

Spatial Variation in Turf Surface Properties of Polo Pitches: A Case Study of Different Handicaps of Argentina

open access: yesAnimals
Polo is a high-speed equestrian sport that imposes mechanical demands on horses and turf, yet limited research has examined the functional behavior of polo playing surfaces.
María Alejandra Blanco   +3 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Mechanical analysis of rock burst induced by fracture and rebound of rock pillar in mining of steeply inclined extra-thick coal seam group

open access: yesMeitan xuebao
In order to reveal the mechanism of breaking and inducing rock pillars between coal seams in steeply inclined and extra thick coal seam group mining, the mining of steeply inclined and extra-thick coal seam group in Wudong Coal Mine is taken as the ...
Shenghu LUO   +8 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Evaluation of Grouting Effectiveness on Cracks in Cement-Stabilized Macadam Layer Based on Pavement Mechanical Response Using FBG Sensors

open access: yesApplied Sciences
Cracking in semi-rigid cement-stabilized macadam bases constitutes a prevalent distress in asphalt pavements. While extensive research exists on grouting materials for crack rehabilitation, quantitative assessment methodologies for treatment efficacy ...
Min Zhang   +4 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Mechanical Response of Super-large Diameter Shield Tunnel Structure under Construction Load Coupled Action

open access: yesChengshi guidao jiaotong yanjiu
[Objective] During construction, super-large diameter shield tunnels are subjected to multiple forces which may easily cause structural damage and waste leakage.
MA Xiaobo
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Mechanisms of the Sympathoadrenal Response to Hypoglycemia

open access: yes, 1997
Publisher Summary The sympathoadrenal response to hypoglycemia plays a key role in glucose counterregulation. In insulin-dependent diabetes, its role becomes even more critical because the glucagon response to hypoglycemia is lost after a short duration of diabetes.
D G, Maggs, R S, Sherwin
openaire   +2 more sources

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