Results 131 to 140 of about 8,095,394 (310)
Applied SciencesThis study deeply explores the permeation deformation mechanism of limestone cores in deep-water environments. Through a customized test device, the mechanical responses of deep-water rocks under different moisture content conditions are simulated.
Chunyao Hou +6 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Nutrition/Dietetics Program's Response to Reviewers' Report
, 2012 Nutrition/Dietetics Program Response to Review Team ReportNutrition/Dietetics Program - Response to Reviewers' ReportNutrition/Dietetics Program - Academic Program ...
Academic Program Reivew +1 more
core
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
, 2019 Magnesium alloys have been at the forefront as possible alternatives to conventional materials such as aluminum and steel for their high specific-strength.
Habib, Saadi
core +1 more source
矿业科学学报This study investigates the mechanical response mechanism and temporary support method of surrounding rock in coal mines under varying unsupported roof distances, with 9103 transportation roadway of Wangzhuang coal mine taken as a case study.
HAO Wenhua +6 more
doaj +1 more source
Response Time of Queueing Mechanisms
SymmetryWe study response time, a key performance characteristic of queueing mechanisms. The studied model incorporates both active and passive queue management, arbitrary service time distribution, as well as a complex model of arrivals. Therefore, the obtained formulas can be used to calculate the response time of many real queueing mechanisms with different
Andrzej Chydzinski, Blazej Adamczyk
openaire +1 more source