Results 81 to 90 of about 2,305,322 (279)

The mechanical response of semiflexible networks to localized perturbations

open access: yes, 2005
Previous research on semiflexible polymers including cytoskeletal networks in cells has suggested the existence of distinct regimes of elastic response, in which the strain field is either uniform (affine) or non-uniform (non-affine) under external ...
A. J. Levine   +7 more
core   +2 more sources

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Mechanical Response of Super-large Diameter Shield Tunnel Structure under Construction Load Coupled Action

open access: yesChengshi guidao jiaotong yanjiu
[Objective] During construction, super-large diameter shield tunnels are subjected to multiple forces which may easily cause structural damage and waste leakage.
MA Xiaobo
doaj   +1 more source

Thermal fluctuations, mechanical response, and hyperuniformity in jammed solids

open access: yes, 2015
Jamming is a geometric phase transition occurring in dense particle systems in the absence of temperature. We use computer simulations to analyse the effect of thermal fluctuations on several signatures of the transition.
Berthier, Ludovic, Ikeda, Atsushi
core   +3 more sources

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Numerical Analysis of Reinforced Concrete Frame Structures with Graphene Oxide and Study of the Earthquake-Resistant Behavior of the Structures Considering the Earthquake in Turkey and Syria (2023)

open access: yesFibers
The earthquake of 6 February 2023, in Turkey and Syria, was catastrophic for many existing buildings. Various reasons have been given to try to understand what happened, since after 2000, changes in construction methods were introduced in this area, with
D. Domínguez-Santos
doaj   +1 more source

Nulling pyrometer uses Kerr cell shutter for fast responses [PDF]

open access: yes, 1965
Conventional pyrometer, in which Kerr cell replaces mechanical shutter and polarizers are added to filters, yields rapid shutter ...

core   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Influence of built-in strain sensor on the mechanical properties of asphalt mixture

open access: yes工程科学学报
The pursuit of intelligence and smartness in road infrastructure is critical for the advancement of road engineering. Embedded strain sensors serve as a vital tool for sensing strain within pavement structures.
Li LIU   +5 more
doaj   +1 more source

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